AU2001232845A1 - Methods for incorporating metal chelators at carboxyl-terminal site of peptides - Google Patents

Methods for incorporating metal chelators at carboxyl-terminal site of peptides

Info

Publication number
AU2001232845A1
AU2001232845A1 AU2001232845A AU3284501A AU2001232845A1 AU 2001232845 A1 AU2001232845 A1 AU 2001232845A1 AU 2001232845 A AU2001232845 A AU 2001232845A AU 3284501 A AU3284501 A AU 3284501A AU 2001232845 A1 AU2001232845 A1 AU 2001232845A1
Authority
AU
Australia
Prior art keywords
peptides
carboxyl
methods
metal chelators
terminal site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001232845A
Inventor
Samuel I. Achilefu
Ananthachari Srinivasan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of AU2001232845A1 publication Critical patent/AU2001232845A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
AU2001232845A 2000-01-21 2001-01-18 Methods for incorporating metal chelators at carboxyl-terminal site of peptides Abandoned AU2001232845A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17722600P 2000-01-21 2000-01-21
US60/177,226 2000-01-21
PCT/US2001/001640 WO2001052898A1 (en) 2000-01-21 2001-01-18 Methods for incorporating metal chelators at carboxyl-terminal site of peptides

Publications (1)

Publication Number Publication Date
AU2001232845A1 true AU2001232845A1 (en) 2001-07-31

Family

ID=22647724

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001232845A Abandoned AU2001232845A1 (en) 2000-01-21 2001-01-18 Methods for incorporating metal chelators at carboxyl-terminal site of peptides

Country Status (2)

Country Link
AU (1) AU2001232845A1 (en)
WO (1) WO2001052898A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10189803B2 (en) 2008-02-22 2019-01-29 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
WO2010011367A2 (en) * 2008-02-22 2010-01-28 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
US10556873B2 (en) 2008-02-22 2020-02-11 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
US10441669B2 (en) 2013-10-04 2019-10-15 Illinois Institute Of Technology Multifunctional chelators, complexes, and compositions thereof, and methods of using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5094950A (en) * 1988-06-07 1992-03-10 Nihon Medi-Physics Co., Ltd. Diethylenetriamine pentaacetic acid derivatives
US5244816A (en) * 1989-10-11 1993-09-14 Akzo N.V. Method for purifying chelator conjugated compounds
AU675166B2 (en) * 1993-10-22 1997-01-23 Nihon Medi-Physics Co., Ltd. Peptide having inflammation affinity and radioactive diagnostic containing the same
WO2000058269A1 (en) * 1999-03-26 2000-10-05 Mallinckrodt Inc. Dtpa esters with orthogonal removable protecting groups

Also Published As

Publication number Publication date
WO2001052898A1 (en) 2001-07-26
WO2001052898A9 (en) 2002-10-31

Similar Documents

Publication Publication Date Title
IL208892A0 (en) Use of hmg fragment as anti-inflammatory agents
AU2001232550A1 (en) Device for metal welding
GB2374442B (en) Method for controlling the order of datagrams
IL160648A0 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
IL160630A0 (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
HK1063467A1 (en) Spiro-hydantoin compounds useful as anti-inflammatory agents
GB0010957D0 (en) Compound & method
PL353299A1 (en) Method of obtaining unsaturated silico-organic compounds
IL157153A0 (en) System for facilitating selection of investments
SG94728A1 (en) Method of cutting csp substrates
AU2001252884A1 (en) Method of dopamine inhibition using l-threo-methylphenidate
AU2001266839A1 (en) Metal skid
AU2001232845A1 (en) Methods for incorporating metal chelators at carboxyl-terminal site of peptides
IL162140A0 (en) Method for the preparation of l-alpha-fluoro corticosteroids
AU4152102A (en) Anti-inflammatory compounds derived from pseudopterogorgia elisabethae
AU2864099A (en) Device for casting of metal
AU2002351532A1 (en) Method of sampling
AU2002360533A1 (en) Method of enhancing phase shift masks
GB0100151D0 (en) Methods of sputtering
AU2002228911A1 (en) Methods for inhibiting pain
AU2752499A (en) Device for casting of metal
GB2383350B (en) Removable anchor for memorials
EP1238585B8 (en) Use of esterquats
AU2002212924A1 (en) Device for casting metal
AU2002246290A1 (en) Superstability of thin-walled structures