DE69413989D1 - Inhalator mit atemstromregelung - Google Patents

Inhalator mit atemstromregelung

Info

Publication number
DE69413989D1
DE69413989D1 DE69413989T DE69413989T DE69413989D1 DE 69413989 D1 DE69413989 D1 DE 69413989D1 DE 69413989 T DE69413989 T DE 69413989T DE 69413989 T DE69413989 T DE 69413989T DE 69413989 D1 DE69413989 D1 DE 69413989D1
Authority
DE
Germany
Prior art keywords
pathway
cross
inhalation
sectional area
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69413989T
Other languages
English (en)
Other versions
DE69413989T2 (de
Inventor
Alastair Robert Clarke
Clive Sleath
Michael Trevor Shepherd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939317198A external-priority patent/GB9317198D0/en
Priority claimed from GB939317197A external-priority patent/GB9317197D0/en
Priority claimed from GB939317196A external-priority patent/GB9317196D0/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of DE69413989D1 publication Critical patent/DE69413989D1/de
Application granted granted Critical
Publication of DE69413989T2 publication Critical patent/DE69413989T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/01—Control of flow without auxiliary power
    • G05D7/0126—Control of flow without auxiliary power the sensing element being a piston or plunger associated with one or more springs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/01—Control of flow without auxiliary power
    • G05D7/0106—Control of flow without auxiliary power the sensing element being a flexible member, e.g. bellows, diaphragm, capsule
    • G05D7/0113—Control of flow without auxiliary power the sensing element being a flexible member, e.g. bellows, diaphragm, capsule the sensing element acting as a valve
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/01—Control of flow without auxiliary power
    • G05D7/0126—Control of flow without auxiliary power the sensing element being a piston or plunger associated with one or more springs
    • G05D7/0133—Control of flow without auxiliary power the sensing element being a piston or plunger associated with one or more springs within the flow-path
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/01—Control of flow without auxiliary power
    • G05D7/0173—Control of flow without auxiliary power using pivoting sensing element acting as a valve mounted within the flow-path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69413989T 1993-08-18 1994-08-18 Inhalator mit atemstromregelung Expired - Lifetime DE69413989T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB939317198A GB9317198D0 (en) 1993-08-18 1993-08-18 Gas flow regulator
GB939317197A GB9317197D0 (en) 1993-08-18 1993-08-18 Gas flow regulator
GB939317196A GB9317196D0 (en) 1993-08-18 1993-08-18 Gas flow regulator
PCT/GB1994/001812 WO1995005208A1 (en) 1993-08-18 1994-08-18 Inhalator with breath flow regulation

Publications (2)

Publication Number Publication Date
DE69413989D1 true DE69413989D1 (de) 1998-11-19
DE69413989T2 DE69413989T2 (de) 1999-04-08

Family

ID=27266819

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69413989T Expired - Lifetime DE69413989T2 (de) 1993-08-18 1994-08-18 Inhalator mit atemstromregelung

Country Status (12)

Country Link
US (2) US5727546A (de)
EP (1) EP0714314B1 (de)
JP (1) JP3545764B2 (de)
AT (1) ATE172124T1 (de)
CA (1) CA2169760C (de)
DE (1) DE69413989T2 (de)
DK (1) DK0714314T3 (de)
ES (1) ES2122319T3 (de)
FI (1) FI114448B (de)
NO (1) NO312436B1 (de)
SG (1) SG82544A1 (de)
WO (1) WO1995005208A1 (de)

Families Citing this family (163)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
JP3328132B2 (ja) * 1996-03-21 2002-09-24 株式会社ユニシアジェックス 吸入式投薬器
GB2312848B (en) * 1996-04-26 1999-11-17 Bespak Plc Controlled flow inhalers
JPH1189935A (ja) * 1997-09-24 1999-04-06 Unisia Jecs Corp 吸入式投薬器
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
CA2228182C (en) * 1998-01-26 2007-03-20 George Volgyesi Breath-powered mist inhaler
JP3488620B2 (ja) * 1998-02-05 2004-01-19 株式会社日立ユニシアオートモティブ 吸入式投薬器
CN1292714B (zh) * 1998-03-16 2012-08-01 诺瓦帝斯公司 气溶胶化活性剂的输送
AU2006201914B2 (en) * 1998-03-16 2008-07-24 Novartis Ag Aerosolized active agent delivery
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
UA73924C2 (en) 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB2344535B (en) * 1998-12-11 2000-10-18 Bespak Plc Inhalation apparatus
FR2787031B1 (fr) * 1998-12-11 2001-03-30 Valois Sa Dispositif d'inhalation ameliore
DE19912461B4 (de) * 1999-03-19 2006-07-20 GSF - Forschungszentrum für Umwelt und Gesundheit GmbH Vorrichtung zur Flußbegrenzung bei niedrigen Differenzdrücken
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
EP1200149B1 (de) * 1999-07-23 2006-09-20 MannKind Corporation Trockenpulverinhalator
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US6427688B1 (en) 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
MXPA02001323A (es) * 2000-05-10 2004-07-16 Alliance Pharma Microgranulos con base fosfolipida para la liberacion de farmaco.
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6453900B1 (en) * 2000-06-09 2002-09-24 Pulmonary Services, Inc. Inhaler device
US6553988B1 (en) * 2000-06-09 2003-04-29 Norton Healthcare, Inc. Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber
US6722360B2 (en) 2000-06-16 2004-04-20 Rajiv Doshi Methods and devices for improving breathing in patients with pulmonary disease
GB2364919A (en) * 2000-07-21 2002-02-13 Cambridge Consultants Inhalers
AU2001283546A1 (en) 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
US6792947B1 (en) * 2000-08-25 2004-09-21 O-Two Systems International Inc. Flow control valve for manual resuscitator devices
SE517226C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator med luftbroms för torrt pulver
FI20002363A0 (fi) * 2000-10-27 2000-10-27 Orion Yhtymae Oyj Jauheinhalaattori
JP4818569B2 (ja) 2000-12-22 2011-11-16 レスメド・リミテッド マスク
US7073499B1 (en) 2001-02-06 2006-07-11 Injet Digital Aerosols Limited Inhaler with airflow regulation
ZA200306564B (en) * 2001-02-26 2004-10-15 Optinose As Nasal devices.
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
DE10126807C2 (de) * 2001-06-01 2003-12-04 Pari Gmbh Inhalationstherapiegerät mit einem Ventil zur Begrenzung des Inspirationsflusses
US6550493B2 (en) * 2001-06-13 2003-04-22 Baxter International Inc. Vacuum demand valve
FI20011317A0 (fi) * 2001-06-20 2001-06-20 Orion Corp Jauheinhalaattori
JP2004531334A (ja) * 2001-06-20 2004-10-14 ネクター セラピューティクス エアゾール薬剤の投与装置及び方法のための流量レギュレータ
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
MXPA04004631A (es) * 2001-11-14 2004-08-12 Nektar Therapeutics Al Corp Aparato en aerosol que comprende cuerpo conectable y pieza de extremo.
US20030094173A1 (en) * 2001-11-14 2003-05-22 Inhale Therapeutic Systems, Inc. Aerosolization device with improved endpiece connection
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US7368102B2 (en) 2001-12-19 2008-05-06 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US6705316B2 (en) 2002-03-11 2004-03-16 Battelle Pulmonary Therapeutics, Inc. Pulmonary dosing system and method
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
US6985798B2 (en) 2002-05-10 2006-01-10 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
US6889690B2 (en) * 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US7118010B2 (en) 2002-05-10 2006-10-10 Oriel Therapeutics, Inc. Apparatus, systems and related methods for dispensing and /or evaluating dry powders
US7677411B2 (en) * 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
SI1535349T1 (sl) * 2002-06-27 2014-10-30 Oriel Therapeutics, Inc. Naprave, sistemi in ustrezni postopki za predelavo, izdajo in/ali vrednotenje nefarmacevtskih suhih praškov
US6887220B2 (en) * 2002-09-12 2005-05-03 Gore Enterprise Holdings, Inc. Catheter having a compliant member configured to regulate aspiration rates
GB0227128D0 (en) * 2002-11-20 2002-12-24 Glaxo Group Ltd A capsule
EP1575648A4 (de) * 2002-12-18 2007-07-04 Glaxo Group Ltd Arzneimittelabgabesystem mit belüftetem mundstück
DK1615689T3 (da) 2003-04-09 2016-03-14 Novartis Ag Apparatur til dannelse af en aerosol og omfattende en opretningsføring til punktering af en kapsel
GB0308969D0 (en) 2003-04-17 2003-05-28 Glaxo Group Ltd Capsules
WO2005025654A1 (en) * 2003-09-16 2005-03-24 Injet Digital Aerosols Limited Inhaler with air flow regulation
US7451761B2 (en) * 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
GB0325628D0 (en) * 2003-11-03 2003-12-10 Glaxo Group Ltd A hand=-held capsule device
BRPI0507884A (pt) * 2004-02-24 2007-08-07 Microdose Technologies Inc método e equipamento para administração de medicamento com base em jato sintético
EP1786784B1 (de) 2004-08-20 2010-10-27 MannKind Corporation Katalyse der diketopiperazinsynthese
CA2578175C (en) 2004-08-23 2014-10-14 Mannkind Corporation Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery
US8061357B2 (en) * 2004-12-08 2011-11-22 Ventus Medical, Inc. Adhesive nasal respiratory devices
US10610228B2 (en) 2004-12-08 2020-04-07 Theravent, Inc. Passive nasal peep devices
US9833354B2 (en) 2004-12-08 2017-12-05 Theravent, Inc. Nasal respiratory devices
AU2005314415B2 (en) * 2004-12-08 2010-11-18 Ventus Medical, Inc. Respiratory devices and methods of use
US7806120B2 (en) * 2004-12-08 2010-10-05 Ventus Medical, Inc. Nasal respiratory devices for positive end-expiratory pressure
ES2290827T3 (es) * 2005-07-06 2008-02-16 Activaero Gmbh Valvula regulable y dispositivo para inhalar.
EP1901793A1 (de) * 2005-07-13 2008-03-26 Cipla Ltd. Inhalator
US7803404B2 (en) 2005-09-14 2010-09-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
CA2653139C (en) * 2006-05-23 2016-01-05 Ventus Medical, Inc. Nasal respiratory devices
US20110203598A1 (en) * 2006-06-07 2011-08-25 Favet Michael L Nasal devices including layered nasal devices and delayed resistance adapters for use with nasal devices
EP2032213A4 (de) * 2006-06-07 2014-02-19 Theravent Inc Vorrichtungen für die nase
AU2007281411A1 (en) * 2006-08-01 2008-02-07 Aradigm Corporation Fluid flow regulating device
EP2668970B1 (de) * 2006-10-25 2016-07-06 Novartis AG Pulverdispersionsvorrichtung
US20080142018A1 (en) * 2006-11-16 2008-06-19 Ventus Medical, Inc. Nasal device applicators
WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
WO2008101991A1 (en) * 2007-02-21 2008-08-28 Novo Nordisk A/S Breath actuation mechanism for an aerosol generating device
US8196576B2 (en) * 2007-02-28 2012-06-12 Microdose Therapeutx, Inc. Inhaler
TW200836781A (en) * 2007-03-07 2008-09-16 Ventus Medical Inc Nasal devices
US8528544B2 (en) * 2007-05-30 2013-09-10 Canon Kabushiki Kaisha Inhaler
US8496002B2 (en) * 2007-06-12 2013-07-30 Civitas Therapeutics, Inc. Powder inhaler devices
US20090064996A1 (en) * 2007-09-10 2009-03-12 Rosh Melvin S Duo chamber
US8020700B2 (en) 2007-12-05 2011-09-20 Ventus Medical, Inc. Packaging and dispensing nasal devices
US20090194109A1 (en) * 2008-02-01 2009-08-06 Rajiv Doshi Cpap interface and backup devices
GB0802028D0 (en) * 2008-02-05 2008-03-12 Dunne Stephen T Powder inhaler flow regulator
CN101980743B (zh) * 2008-03-27 2014-04-02 曼金德公司 干燥粉末吸入系统
US8539951B1 (en) 2008-05-27 2013-09-24 Trudell Medical International Oscillating positive respiratory pressure device
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2570147B1 (de) 2008-06-13 2017-10-18 MannKind Corporation Trockenpulverinhalator und System zur Wirkstofffreisetzung
US20090308398A1 (en) * 2008-06-16 2009-12-17 Arthur Ferdinand Adjustable resistance nasal devices
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
WO2010031040A2 (en) * 2008-09-15 2010-03-18 Ventus Medical, Inc. Nasal devices, systems and methods
US8517010B2 (en) * 2008-09-26 2013-08-27 Stamford Devices Limited Nebuliser system
US8327849B2 (en) 2008-10-28 2012-12-11 Trudell Medical International Oscillating positive expiratory pressure device
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8408242B2 (en) * 2009-02-04 2013-04-02 Edward S Chang Overflow shutoff valve
US8485179B1 (en) 2009-02-23 2013-07-16 Trudell Medical International Oscillating positive expiratory pressure device
US9149589B2 (en) 2009-02-23 2015-10-06 Trudell Medical International Method and device for performing orientation dependent oscillating positive expiratory pressure therapy
PL2405963T3 (pl) 2009-03-11 2014-04-30 Mannkind Corp Urządzenie, układ i sposób pomiaru oporu inhalatora
WO2010135672A1 (en) * 2009-05-21 2010-11-25 Microdose Therapeutx, Inc. Rotary cassette system for dry powder inhaler
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
KR20180079458A (ko) 2009-06-12 2018-07-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
US20110000481A1 (en) * 2009-07-01 2011-01-06 Anand Gumaste Nebulizer for infants and respiratory compromised patients
ES2391000T3 (es) * 2009-08-06 2012-11-20 Activaero Gmbh Dispositivo para la limitación de flujo a presiones diferenciales bajas
EP2496295A1 (de) 2009-11-03 2012-09-12 MannKind Corporation Vorrichtung und verfahren zur simulation von einatmungsanstrengungen
US20110108041A1 (en) * 2009-11-06 2011-05-12 Elliot Sather Nasal devices having a safe failure mode and remotely activatable
WO2011079310A1 (en) 2009-12-23 2011-06-30 Map Pharmaceuticals,Inc. Enhanced eductor design
WO2011080761A1 (en) * 2009-12-30 2011-07-07 Thirumalai Anadampillai Aparna An improved dry powder inhaler
EP3431128A1 (de) 2010-01-05 2019-01-23 MicroDose Therapeutx, Inc. Inhalationsvorrichtung
US8875711B2 (en) 2010-05-27 2014-11-04 Theravent, Inc. Layered nasal respiratory devices
JP5543850B2 (ja) * 2010-06-15 2014-07-09 独立行政法人物質・材料研究機構 粉末状薬剤吸入デバイス
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
CA2837057C (en) 2011-06-06 2018-08-28 Trudell Medical International Oscillating positive expiratory pressure device
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US9517315B2 (en) 2012-11-30 2016-12-13 Trudell Medical International Oscillating positive expiratory pressure device
AU2014222494B2 (en) * 2013-03-01 2017-09-07 Draeger Safety Uk Limited Valve assembly
CA2906817C (en) 2013-03-15 2022-01-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US9849257B2 (en) 2013-08-22 2017-12-26 Trudell Medical International Oscillating positive respiratory pressure device
CA2936462A1 (en) * 2014-01-24 2015-07-30 Aerocrine Ab Miniaturized fluid flow regulating device
US10363383B2 (en) 2014-02-07 2019-07-30 Trudell Medical International Pressure indicator for an oscillating positive expiratory pressure device
CN106255524B (zh) 2014-02-21 2020-03-24 大卫·布朗 用于吸入粉体的吸入装置
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10471222B2 (en) 2014-07-01 2019-11-12 Dance Biopharm Inc. Aerosolization system with flow restrictor and feedback device
US10857313B2 (en) 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
US11273271B2 (en) 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
US20160033051A1 (en) * 2014-07-31 2016-02-04 Parker-Hannifin Corporation Shutoff valve assembly
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP4134118A3 (de) 2015-07-30 2023-05-03 Trudell Medical International Kombiniertes atemmuskeltraining und oszillierende vorrichtung für positiven ausatmungsdruck
GB2542376A (en) * 2015-09-16 2017-03-22 Nicoventures Holdings Ltd Aerosol provision system with variable airflow
US10857317B2 (en) 2015-12-04 2020-12-08 Trudell Medical International Huff cough simulation device
ES2882032T3 (es) * 2015-12-21 2021-12-01 Kindeva Drug Delivery Lp Conjuntos reguladores de flujo para uso en inhaladores medicinales
JP7152954B2 (ja) * 2015-12-21 2022-10-13 キンデーバ ドラッグ デリバリー リミティド パートナーシップ 医療用吸入器
US11376378B2 (en) 2015-12-21 2022-07-05 Kindeva Drug Delivery, L.P. Flow governors for use in medicinal inhalers
US10512921B2 (en) * 2016-05-09 2019-12-24 Funai Electric Co., Ltd. Maintenance apparatus for vaporizing device
CA3225148A1 (en) 2016-05-19 2017-11-23 Mannkind Corporation Apparatus, system and method for detecting and monitoring inhalations
WO2018071443A1 (en) 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
JP7061124B2 (ja) * 2016-11-30 2022-04-27 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 渦巻状端部プラグを備えた吸入器
CA3037824A1 (en) * 2016-11-30 2018-06-07 Gerard Zuber Inhaler with sized cavity
US10813881B2 (en) * 2017-04-28 2020-10-27 Otitopic Inc. Dry powder inhalation device
CA3059532A1 (en) 2017-05-03 2018-11-08 Trudell Medical International Combined oscillating positive expiratory pressure therapy and huff cough simulation device
WO2019002480A1 (en) * 2017-06-29 2019-01-03 Plastic Omnium Advanced Innovation And Research VENTILATION FLOW REGULATOR FOR VEHICLE TANK UNDER PRESSURE
US10953278B2 (en) 2018-02-02 2021-03-23 Trudell Medical International Oscillating positive expiratory pressure device
WO2019186372A1 (en) * 2018-03-26 2019-10-03 Philip Morris Products S.A. Inhaler with vortex capsule cavity
JP7464998B2 (ja) * 2018-06-01 2024-04-10 セーフビーブイエム コーポレイション バッグバルブマスクのための圧力安全デバイス
CN110833415A (zh) * 2018-08-15 2020-02-25 深圳市美好创亿医疗科技有限公司 呼气no检测系统
US11717621B2 (en) 2019-06-24 2023-08-08 De Motu Cordis Pty Ltd Automatic dispenser for respiratory delivery device
US11793951B2 (en) 2019-06-24 2023-10-24 De Motu Cordis Pty Ltd Automatic dispenser for respiratory delivery device and method
US10828432B1 (en) * 2019-06-24 2020-11-10 De Motu Cordis Pty Ltd Respiratory delivery device and method
CN113357216B (zh) * 2021-07-08 2022-11-15 哈尔滨碧研科技有限公司 一种气路集成装置及阀块系统
EP4373337A1 (de) * 2021-07-21 2024-05-29 JT International SA 6h-imidazo[1,2-a pyrrolo[2,3-e pyridinderivate zur therapeutischen verwendung

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB610309A (en) * 1943-07-05 1948-10-14 Dole Valve Co Improvements in or relating to fluid control devices and method of controlling the flow of fluid
GB643262A (en) * 1944-07-17 1950-09-15 Dole Valve Co Improvements in or relating to fluid control devices
IL26014A (en) * 1965-06-28 1971-03-24 Fahre O Automatic regulating valve for ventilation plants
US3669113A (en) * 1966-03-07 1972-06-13 Fisons Ltd Inhalation device
DE1566631B1 (de) * 1968-05-23 1970-05-27 Draegerwerk Ag Oberflaechenverdunster fuer die Verwendung in Narkosekreissystemen
GB1308322A (en) * 1970-01-01 1973-02-21 Barber Colman Co Constant mass flow control device
US3837362A (en) * 1972-05-23 1974-09-24 Eaton Corp Fluid flow control
US3874378A (en) * 1973-09-06 1975-04-01 Globe Safety Products Inc Combined resuscitator and inhalator apparatus
GB1487676A (en) * 1974-09-23 1977-10-05 Christianson R Demand regulator for a breathing apparatus
US3970105A (en) * 1975-06-16 1976-07-20 Continental Can Company, Inc. Toroidal pressure regulator
US4092999A (en) * 1977-04-25 1978-06-06 Dana Corporation Fluid control valve
CA1120372A (en) * 1978-02-13 1982-03-23 Max Isaacson Demand inhalation valve system
US4259951A (en) * 1979-07-30 1981-04-07 Chesebrough-Pond's Inc. Dual valve for respiratory device
GB2104393B (en) * 1981-08-13 1984-11-07 Glaxo Group Ltd Medical inhalation devices
US7025784B1 (en) * 1981-10-29 2006-04-11 Hansa Medical Products, Inc. Method and apparatus for a tracheal valve
FR2517209A1 (fr) * 1981-12-01 1983-06-03 Intertechnique Sa Injecteur annulaire, notamment pour dilution dans un regulateur respiratoire a la demande
US4535767A (en) * 1982-10-01 1985-08-20 Tiep Brian L Oxygen delivery apparatus
FR2519254B1 (fr) * 1982-11-26 1988-05-06 Cuvier Claude Dispositif de circulation d'air a double courant module dans les alveoles pulmonaires
ES8601500A1 (es) * 1983-12-28 1985-11-01 Coxwold Pty Ltd Un conjunto de valvula
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
GB2169810B (en) * 1985-01-11 1988-05-25 Coal Ind Simulator
EP0198708B1 (de) * 1985-04-15 1991-06-12 Nippon Tansan Gas Co., Ltd. Tragbares Sauerstoffinhalationsgerät
DE3636669C2 (de) * 1986-10-28 2001-08-16 Siemens Ag Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten
US5309904A (en) * 1991-01-28 1994-05-10 Beck Blaine E Insufflating/suctioning valve
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
CH685475A5 (fr) * 1992-04-10 1995-07-31 Varioraw Percutive Sa Appareil thérapeutique spécifique du domaine respiratoire.
DE69413528T2 (de) * 1993-04-06 1999-05-06 Minnesota Mining & Mfg Vorrichtung zum deagglomerieren für trockenpulverinhalatoren
ATE182801T1 (de) * 1993-05-28 1999-08-15 Pari Gmbh Mundstück für inhalationstherapiegeräte
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow

Also Published As

Publication number Publication date
EP0714314B1 (de) 1998-10-14
CA2169760C (en) 2006-06-06
DK0714314T3 (da) 1999-06-23
EP0714314A1 (de) 1996-06-05
JPH09501581A (ja) 1997-02-18
FI960704A (fi) 1996-02-16
FI960704A0 (fi) 1996-02-16
NO960610D0 (no) 1996-02-15
WO1995005208A1 (en) 1995-02-23
NO312436B1 (no) 2002-05-13
ATE172124T1 (de) 1998-10-15
SG82544A1 (en) 2001-08-21
US5727546A (en) 1998-03-17
DE69413989T2 (de) 1999-04-08
CA2169760A1 (en) 1995-02-23
US6109261A (en) 2000-08-29
ES2122319T3 (es) 1998-12-16
FI114448B (fi) 2004-10-29
NO960610L (no) 1996-03-28
JP3545764B2 (ja) 2004-07-21

Similar Documents

Publication Publication Date Title
DE69413989D1 (de) Inhalator mit atemstromregelung
US5878743A (en) Pressure sensitive flow control valve
EP0831950B1 (de) Pneumatisch betriebene gasbedarfsvorrichtung
US3362404A (en) Respiration apparatus for administering intermittent positive pressure breathing therapy
AU712312B2 (en) Breathing circuit apparatus for a nebulizer
US5740799A (en) Device for the supply of oxygen and/or other gases to a patient
US4278110A (en) Demand responsive flow controller
ATE27405T1 (de) Beatmungsventil.
SE9700937D0 (sv) Powder inhaler I
DK0983103T3 (da) Indretning til indgivelse af en medicinsk aerosol via lungen
PT1003583E (pt) Inalador para medicamento em po seco que tem um meio de desvio de fluxo activado por inalacao para desencadear a administracao do medicamento
DE69931265D1 (de) Inhalator
JP4741135B2 (ja) 加圧流体の供給制御のためのバルブ装置
IL105930A (en) Therapeutic respiration device
ATE270910T1 (de) Inhalator
US6425396B1 (en) Sensing valve motion limiting mechanism for respiratory equipment
US5241955A (en) Breathing apparatus
US20100043790A1 (en) Nebuliser valve
WO2001076658A3 (en) Neo-natal oxygen delivery system
SE9802398D0 (sv) Inhalation device
US6105929A (en) Control valve for gas supply to a nebulizer
JPS632043Y2 (de)
GB1286839A (en) Valve for use in conjunction with a positive pressure flow cut-off respiration system
ES1033586U (es) Dispositivo para la administracion de medicion en aerosol.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition