DE69409830T2 - Markieren von nukleinsäureanalogen peptid-chimären - Google Patents

Markieren von nukleinsäureanalogen peptid-chimären

Info

Publication number
DE69409830T2
DE69409830T2 DE69409830T DE69409830T DE69409830T2 DE 69409830 T2 DE69409830 T2 DE 69409830T2 DE 69409830 T DE69409830 T DE 69409830T DE 69409830 T DE69409830 T DE 69409830T DE 69409830 T2 DE69409830 T2 DE 69409830T2
Authority
DE
Germany
Prior art keywords
nucleic acid
chimeres
acid analog
analog peptide
labeling nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69409830T
Other languages
English (en)
Other versions
DE69409830D1 (de
Inventor
Henrik Orum
Peter Eigil Prof Dr Nielsen
Christopher John Stanley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PNA Diagnostics ApS Denmark
Original Assignee
PNA Diagnostics ApS Denmark
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PNA Diagnostics ApS Denmark filed Critical PNA Diagnostics ApS Denmark
Publication of DE69409830D1 publication Critical patent/DE69409830D1/de
Application granted granted Critical
Publication of DE69409830T2 publication Critical patent/DE69409830T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003—Peptide-nucleic acids (PNAs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69409830T 1993-12-06 1994-11-30 Markieren von nukleinsäureanalogen peptid-chimären Expired - Fee Related DE69409830T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9324956A GB2289677A (en) 1993-12-06 1993-12-06 Labelling of nucleic acid analogue-peptide chimerae
PCT/EP1994/003972 WO1995016202A1 (en) 1993-12-06 1994-11-30 Labelling of nucleic acid analogue-peptide chimerae

Publications (2)

Publication Number Publication Date
DE69409830D1 DE69409830D1 (de) 1998-05-28
DE69409830T2 true DE69409830T2 (de) 1998-09-24

Family

ID=10746181

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409830T Expired - Fee Related DE69409830T2 (de) 1993-12-06 1994-11-30 Markieren von nukleinsäureanalogen peptid-chimären

Country Status (12)

Country Link
EP (1) EP0733206B1 (de)
JP (1) JP3574134B2 (de)
KR (1) KR100196083B1 (de)
AT (1) ATE165448T1 (de)
AU (1) AU678877B2 (de)
CA (1) CA2177604C (de)
DE (1) DE69409830T2 (de)
DK (1) DK0733206T3 (de)
ES (1) ES2116718T3 (de)
GB (1) GB2289677A (de)
WO (1) WO1995016202A1 (de)
ZA (1) ZA949642B (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700310B2 (en) 2002-09-06 2010-04-20 Promega Corporation Method for detecting transferase enzymatic activity
US7741067B2 (en) 2002-12-23 2010-06-22 Promega Corporation Luciferase-based assays

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223833B1 (en) 1991-05-24 2007-05-29 Isis Pharmaceuticals, Inc. Peptide nucleic acid conjugates
JP3307945B2 (ja) * 1994-10-06 2002-07-29 アイシス・ファーマシューティカルス・インコーポレーテッド ペプチド核酸コンジュゲート
US5744181A (en) * 1995-03-01 1998-04-28 W. R. Grace & Co.-Conn. Packaging method using thermoplastic materials and package obtained thereby
WO1997014793A1 (en) * 1995-10-20 1997-04-24 Trustees Of Boston University Nucleic acid clamps
GB9712818D0 (en) * 1996-07-08 1997-08-20 Cambridge Antibody Tech Labelling and selection of specific binding molecules
DE19712530A1 (de) * 1997-03-25 1998-10-01 Boehringer Mannheim Gmbh Neue Monomerbausteine zur Markierung von peptidischen Nukleinsäuren
US6617422B1 (en) 1997-05-23 2003-09-09 Peter Nielsen Peptide nucleic acid monomers and oligomers
AU2002250262B9 (en) 2001-03-09 2006-11-30 Boston Probes, Inc. Methods, kits and compositions of combination oligomers
DE102006034319A1 (de) * 2006-07-21 2008-01-31 Ugichem Gmbh Chirale mit Phosponsäurester- oder Phosphonsäure- substituierte Verbindungen
MA39171A1 (fr) 2014-01-10 2017-07-31 Glaxosmithkline Intellectual Property (No 2) Ltd Dérivés d'hydroxy formamide et leur utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923802A (en) * 1985-06-13 1990-05-08 Immunex Corporation Peptide substrates for the detection, characterization and purification of protein kinase C
JPH072980B2 (ja) * 1990-09-20 1995-01-18 大同メタル工業株式会社 複合摺動材料
WO1992020793A1 (en) * 1991-05-10 1992-11-26 The Salk Institute For Biological Studies CLONING AND RECOMBINANT PRODUCTION OF RECEPTOR(S) OF THE ACTIVIN/TGF-β SUPERFAMILY
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700310B2 (en) 2002-09-06 2010-04-20 Promega Corporation Method for detecting transferase enzymatic activity
US7741067B2 (en) 2002-12-23 2010-06-22 Promega Corporation Luciferase-based assays
US8361739B2 (en) 2002-12-23 2013-01-29 Promega Corporation Luciferase-based assays
US8603767B2 (en) 2002-12-23 2013-12-10 Promega Corporation Luciferase-based assays
US8859220B2 (en) 2002-12-23 2014-10-14 Promega Corporation Luciferase-based assays
US9631225B2 (en) 2002-12-23 2017-04-25 Promega Corporation Luciferase-based assays

Also Published As

Publication number Publication date
ATE165448T1 (de) 1998-05-15
JP3574134B2 (ja) 2004-10-06
DK0733206T3 (da) 1999-02-01
EP0733206B1 (de) 1998-04-22
KR100196083B1 (ko) 1999-06-15
JPH09506358A (ja) 1997-06-24
AU678877B2 (en) 1997-06-12
EP0733206A1 (de) 1996-09-25
KR960706640A (ko) 1996-12-09
CA2177604C (en) 2001-01-30
AU1272895A (en) 1995-06-27
DE69409830D1 (de) 1998-05-28
GB2289677A (en) 1995-11-29
CA2177604A1 (en) 1995-06-15
ES2116718T3 (es) 1998-07-16
ZA949642B (en) 1996-06-05
GB9324956D0 (en) 1994-01-26
WO1995016202A1 (en) 1995-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee