DE69333670D1 - Vom mage-3-gen abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen - Google Patents

Vom mage-3-gen abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen

Info

Publication number
DE69333670D1
DE69333670D1 DE69333670T DE69333670T DE69333670D1 DE 69333670 D1 DE69333670 D1 DE 69333670D1 DE 69333670 T DE69333670 T DE 69333670T DE 69333670 T DE69333670 T DE 69333670T DE 69333670 D1 DE69333670 D1 DE 69333670D1
Authority
DE
Germany
Prior art keywords
hla
derived
mage
gene
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333670T
Other languages
English (en)
Other versions
DE69333670T2 (de
Inventor
Thierry Boon-Falleur
Der Bruggen Pierre Van
Plaen Etienne De
Christophe Lurquin
Catia Traversari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research New York
Original Assignee
Ludwig Institute for Cancer Research New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/938,334 external-priority patent/US5405940A/en
Priority claimed from US08/037,230 external-priority patent/US6235525B1/en
Priority claimed from US08/073,103 external-priority patent/US5462871A/en
Application filed by Ludwig Institute for Cancer Research New York filed Critical Ludwig Institute for Cancer Research New York
Publication of DE69333670D1 publication Critical patent/DE69333670D1/de
Application granted granted Critical
Publication of DE69333670T2 publication Critical patent/DE69333670T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
DE69333670T 1992-08-31 1993-08-30 Vom mage-3-gen abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen Expired - Lifetime DE69333670T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US07/938,334 US5405940A (en) 1992-08-31 1992-08-31 Isolated nonapeptides derived from MAGE genes and uses thereof
US938334 1992-08-31
US08/037,230 US6235525B1 (en) 1991-05-23 1993-03-26 Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof
US37230 1993-03-26
US73103 1993-06-07
US08/073,103 US5462871A (en) 1992-08-31 1993-06-07 Isolated nucleic acid molecules which encode MAGE derived nonapeptides
PCT/US1993/008157 WO1994005304A1 (en) 1992-08-31 1993-08-30 Isolated nonapeptide derived from mage-3 gene and presented by hla-a1, and uses thereof

Publications (2)

Publication Number Publication Date
DE69333670D1 true DE69333670D1 (de) 2004-11-25
DE69333670T2 DE69333670T2 (de) 2005-03-10

Family

ID=26713936

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333670T Expired - Lifetime DE69333670T2 (de) 1992-08-31 1993-08-30 Vom mage-3-gen abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen

Country Status (12)

Country Link
US (2) US6379901B1 (de)
EP (1) EP0658113B1 (de)
JP (1) JP3608788B2 (de)
AT (2) ATE280180T1 (de)
AU (1) AU668772B2 (de)
CA (1) CA2143335C (de)
DE (1) DE69333670T2 (de)
DK (1) DK0658113T3 (de)
ES (1) ES2225824T3 (de)
FI (1) FI950887A (de)
PT (1) PT658113E (de)
WO (1) WO1994005304A1 (de)

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US6951917B1 (en) 1995-09-26 2005-10-04 The United States Of America As Represented By The Department Of Health And Human Services MHC-class II restricted melanoma antigens and their use in therapeutic methods
US7501501B2 (en) 1995-09-26 2009-03-10 The United States Of America As Represented By The Secretary Department Of Health And Human Services MHC-Class II restricted melanoma antigens and their use in therapeutic methods
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US5965535A (en) * 1997-09-12 1999-10-12 Ludwig Institute For Cancer Research Mage-3 peptides presented by HLA class II molecules
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DE60124899T2 (de) 2000-05-10 2007-08-16 Sanofi Pasteur Ltd., Toronto Durch mage minigene kodierte immunogene polypeptide und ihre verwendungen
US7083789B2 (en) 2000-12-04 2006-08-01 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
AU2002306600A1 (en) * 2001-02-26 2002-09-12 Albany Medical College Sperm protein 17 for the diagnosis and treatment of cancer
AU2002244862B2 (en) 2001-04-12 2007-09-20 Imperial Innovations Limited Diagnosis and treatment of cancer: I
US7892559B2 (en) 2002-01-30 2011-02-22 Survac Aps Survivin-derived peptides and use thereof
AU2004280608B2 (en) * 2002-04-09 2012-04-05 Sanofi Pasteur, Inc. Modified CEA/B7 vector
DE60315628T2 (de) 2002-04-09 2008-06-05 Sanofi Pasteur Ltd., Toronto Modifizierte cea nucleinsäure und expressionsvektoren
CA2510238A1 (en) * 2002-10-22 2004-05-06 Sanofi Pasteur Limited Cancer treatment using vaccine and high-dose cytokine
ES2661082T3 (es) 2003-01-30 2018-03-27 Survac Aps Péptidos derivados de survivina y uso de los mismos
PL2087904T3 (pl) 2003-11-19 2014-01-31 Survac Aps Zastosowanie terapeutyczne peptydów pochodzących z białek BcL-XL u pacjentów z rakiem
WO2006113540A2 (en) 2005-04-14 2006-10-26 Duke University Use of ntrosylated hemoglobin
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي Pi-3 inhibitors and methods of use
AR060358A1 (es) 2006-04-06 2008-06-11 Novartis Vaccines & Diagnostic Quinazolinas para la inhibicion de pdk 1
US8940771B2 (en) 2007-12-20 2015-01-27 Novartis Ag Organic compounds
US8293753B2 (en) 2009-07-02 2012-10-23 Novartis Ag Substituted 2-carboxamide cycloamino ureas
RU2012139182A (ru) 2010-02-22 2014-03-27 Ф. Хоффманн-Ля Рош Аг ПИРИДО[3,2-d]ПИРИМИДИНЫ - ИНГИБИТОРЫ PI3К ДЕЛЬТА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
AR082418A1 (es) 2010-08-02 2012-12-05 Novartis Ag Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
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CN104039790B (zh) 2011-10-28 2016-04-13 诺华股份有限公司 嘌呤衍生物及它们在治疗疾病中的应用
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EP3744340A3 (de) 2015-07-16 2021-03-03 Biokine Therapeutics Ltd. Zusammensetzungen und verfahren zur behandlung von krebs
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SI3565828T1 (sl) 2017-01-05 2022-04-29 Kahr Medical Ltd. SIRP1 alfa-41BBL fuzijski protein in postopki za njegovo uporabo
AU2018205888B2 (en) 2017-01-05 2021-09-02 Kahr Medical Ltd. A PD1-41BBL fusion protein and methods of use thereof
GB201700345D0 (en) 2017-01-09 2017-02-22 F-Star Beta Ltd Conditional agonists of immune responses
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WO2019006003A1 (en) 2017-06-27 2019-01-03 The Trustees Of Princeton University COMPOSITIONS AND METHODS FOR IMPROVING IMMUNOTHERAPY
GB201713078D0 (en) 2017-08-15 2017-09-27 Adaptimmune Ltd T Cell Modification
EP3743093A1 (de) 2018-01-26 2020-12-02 Cambridge Enterprise Limited Peptidaustauschprotein
MX2021000263A (es) 2018-07-11 2021-05-12 Kahr Medical Ltd Proteina de fusion variante sirpalfa-4-1bbl y procedimientos de uso de la misma.
GB201811404D0 (en) 2018-07-12 2018-08-29 F Star Beta Ltd Anti-CD137 Antibodies
GB201811410D0 (en) 2018-07-12 2018-08-29 F Star Beta Ltd OX40 Binding molecules
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GB201820444D0 (en) 2018-12-14 2019-01-30 Adaptimmune Ltd Marker for T cell expansion
KR20220044284A (ko) 2019-07-11 2022-04-07 카 메디컬 리미티드 이종이량체 및 이의 사용방법
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Also Published As

Publication number Publication date
ATE378406T1 (de) 2007-11-15
WO1994005304A1 (en) 1994-03-17
EP0658113A4 (de) 1997-11-26
PT658113E (pt) 2005-03-31
ES2225824T3 (es) 2005-03-16
AU668772B2 (en) 1996-05-16
JP3608788B2 (ja) 2005-01-12
FI950887A0 (fi) 1995-02-27
DK0658113T3 (da) 2005-02-14
FI950887A (fi) 1995-02-27
AU5096993A (en) 1994-03-29
US5695994A (en) 1997-12-09
CA2143335A1 (en) 1994-03-17
EP0658113A1 (de) 1995-06-21
JPH08500837A (ja) 1996-01-30
ATE280180T1 (de) 2004-11-15
US6379901B1 (en) 2002-04-30
DE69333670T2 (de) 2005-03-10
EP0658113B1 (de) 2004-10-20
CA2143335C (en) 2000-03-14

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