DE69333241D1 - Reinigung von faktor ix - Google Patents

Reinigung von faktor ix

Info

Publication number
DE69333241D1
DE69333241D1 DE69333241T DE69333241T DE69333241D1 DE 69333241 D1 DE69333241 D1 DE 69333241D1 DE 69333241 T DE69333241 T DE 69333241T DE 69333241 T DE69333241 T DE 69333241T DE 69333241 D1 DE69333241 D1 DE 69333241D1
Authority
DE
Germany
Prior art keywords
cleaning factor
cleaning
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333241T
Other languages
English (en)
Other versions
DE69333241T2 (de
Inventor
W Herring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Therapeutic Corp
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Application granted granted Critical
Publication of DE69333241D1 publication Critical patent/DE69333241D1/de
Publication of DE69333241T2 publication Critical patent/DE69333241T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69333241T 1992-07-14 1993-07-13 Reinigung von faktor ix Expired - Lifetime DE69333241T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/913,666 US5286849A (en) 1992-07-14 1992-07-14 Purification of factor IX
US913666 1992-07-14
PCT/US1993/006610 WO1994001120A1 (en) 1992-07-14 1993-07-13 Purification of factor ix

Publications (2)

Publication Number Publication Date
DE69333241D1 true DE69333241D1 (de) 2003-11-13
DE69333241T2 DE69333241T2 (de) 2004-07-22

Family

ID=25433483

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333241T Expired - Lifetime DE69333241T2 (de) 1992-07-14 1993-07-13 Reinigung von faktor ix

Country Status (7)

Country Link
US (1) US5286849A (de)
EP (1) EP0650364B1 (de)
JP (1) JP2839712B2 (de)
CA (1) CA2139931C (de)
DE (1) DE69333241T2 (de)
ES (1) ES2206459T3 (de)
WO (1) WO1994001120A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
JP2007524607A (ja) * 2003-04-09 2007-08-30 ワイス 凝固因子の吸入による血友病処置
TR201911082T4 (tr) * 2010-03-30 2019-08-21 Octapharma Ag K vitaminine bağımlı proteinlerin saflaştırılması için bir işlem.
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725673A (en) * 1986-08-29 1988-02-16 Alpha Therapeutic Corporation Plasma fraction purification using silica resin bound to a ligand

Also Published As

Publication number Publication date
DE69333241T2 (de) 2004-07-22
CA2139931C (en) 2001-01-30
CA2139931A1 (en) 1994-01-20
US5286849A (en) 1994-02-15
EP0650364A1 (de) 1995-05-03
ES2206459T3 (es) 2004-05-16
EP0650364A4 (de) 1996-05-29
EP0650364B1 (de) 2003-10-08
WO1994001120A1 (en) 1994-01-20
AU4677293A (en) 1994-01-31
JPH07508989A (ja) 1995-10-05
AU665452B2 (en) 1996-01-04
JP2839712B2 (ja) 1998-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition