DE69330920T2 - Integrative Genexpression in Mikroorganismen mit Nahrungsmittelqualität - Google Patents

Integrative Genexpression in Mikroorganismen mit Nahrungsmittelqualität

Info

Publication number
DE69330920T2
DE69330920T2 DE69330920T DE69330920T DE69330920T2 DE 69330920 T2 DE69330920 T2 DE 69330920T2 DE 69330920 T DE69330920 T DE 69330920T DE 69330920 T DE69330920 T DE 69330920T DE 69330920 T2 DE69330920 T2 DE 69330920T2
Authority
DE
Germany
Prior art keywords
operon
gene expression
microorganism
gene
food grade
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69330920T
Other languages
English (en)
Other versions
DE69330920D1 (de
Inventor
Jan Knol
Olivier Marciset
Beat Mollet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe des Produits Nestle SA, Nestle SA filed Critical Societe des Produits Nestle SA
Publication of DE69330920D1 publication Critical patent/DE69330920D1/de
Application granted granted Critical
Publication of DE69330920T2 publication Critical patent/DE69330920T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12N9/1033—Chloramphenicol O-acetyltransferase (2.3.1.28)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Dairy Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69330920T 1992-04-07 1993-03-31 Integrative Genexpression in Mikroorganismen mit Nahrungsmittelqualität Expired - Fee Related DE69330920T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92105973A EP0569604A1 (de) 1992-04-07 1992-04-07 Integrative Genexpression in Streptococcus sulivarius ssp. thermophilus

Publications (2)

Publication Number Publication Date
DE69330920D1 DE69330920D1 (de) 2001-11-22
DE69330920T2 true DE69330920T2 (de) 2002-06-20

Family

ID=8209519

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69330920T Expired - Fee Related DE69330920T2 (de) 1992-04-07 1993-03-31 Integrative Genexpression in Mikroorganismen mit Nahrungsmittelqualität

Country Status (11)

Country Link
US (1) US5491079A (de)
EP (3) EP0569604A1 (de)
JP (1) JP2634365B2 (de)
AT (1) ATE207123T1 (de)
AU (1) AU665626B2 (de)
BR (1) BR9301468A (de)
CA (1) CA2093152C (de)
DE (1) DE69330920T2 (de)
DK (1) DK0564965T3 (de)
MX (1) MX9302042A (de)
NZ (1) NZ247338A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996032486A1 (en) * 1995-04-11 1996-10-17 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Method for the construction of vectors for lactic acid bacteria like lactobacillus such that the bacteria can efficiently express, secrete and display proteins at the surface
DK1808485T3 (da) * 2000-03-31 2009-11-02 Centre Nat Rech Scient Mutanter af lactobacillus casei, der er mangelfuld med hensyn til regulering af carbonkatobolisme
US6762040B2 (en) 2000-05-24 2004-07-13 Novozymes A/S Method for increasing gene copy number in a host cell and resulting host cell
US6861258B2 (en) * 2002-02-28 2005-03-01 Gas Technology Institute System and method for introduction and stabilization of genes in Thermus sp.
GB0501540D0 (en) * 2005-01-25 2005-03-02 Univ Leeds Controlled production and delivery of biologically active agents by gut bacteria
RU2766157C2 (ru) 2011-06-01 2022-02-08 Интрексон Актобиотикс Н.В. Система полицистронной экспрессии для бактерий
US9187301B2 (en) 2013-04-22 2015-11-17 Jlg Industries, Inc. Self-propel accessory
CN106661543A (zh) * 2014-06-17 2017-05-10 Xycrobe治疗公司 经遗传修饰的细菌和用于细菌的遗传修饰的方法
WO2017044835A1 (en) * 2015-09-10 2017-03-16 Xycrobe Therapeutics, Inc. Genetically modified bacteria, compositions and methods of making and using
CN108883140A (zh) 2016-01-14 2018-11-23 英特瑞克斯顿阿克图比奥帝克斯有限公司 治疗1型糖尿病的组合物和方法
WO2017147507A1 (en) 2016-02-24 2017-08-31 Xycrobe Therapeutics, Inc. Skin probiotic formulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801529A (nl) * 1988-06-15 1990-01-02 Nl Zuivelonderzoek Inst Werkwijze voor het selecteren en stabiel handhaven van recombinant dna in melkzuurbacterien.
EP0487159A1 (de) * 1990-11-23 1992-05-27 Unilever N.V. Für die Transformation von lebensmittelnsicheren Wirtszellen geeigneter Vektor, seine Verwendung für solche Transformationen und Verwendung der transformierten Zellen in Biotransformationsprozessen
US5395761A (en) * 1991-11-27 1995-03-07 Eli Lilly And Company Plasmid pHKY334, an expression vector for EK-BGH and host cells transformed therewith

Also Published As

Publication number Publication date
JP2634365B2 (ja) 1997-07-23
BR9301468A (pt) 1993-10-13
EP0965641A2 (de) 1999-12-22
EP0965641A3 (de) 2000-03-22
CA2093152A1 (en) 1993-10-08
EP0569604A1 (de) 1993-11-18
DK0564965T3 (da) 2002-02-11
ATE207123T1 (de) 2001-11-15
CA2093152C (en) 1999-01-19
MX9302042A (es) 1994-07-29
DE69330920D1 (de) 2001-11-22
AU3670993A (en) 1993-10-14
EP0564965B1 (de) 2001-10-17
NZ247338A (en) 1995-08-28
EP0564965A2 (de) 1993-10-13
EP0564965A3 (en) 1994-06-29
US5491079A (en) 1996-02-13
JPH0654692A (ja) 1994-03-01
AU665626B2 (en) 1996-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee