DE69329824D1 - Nachweis und amplifikation bestimmter nukleinsäuren mittels exonukleolytischer aktivität - Google Patents

Nachweis und amplifikation bestimmter nukleinsäuren mittels exonukleolytischer aktivität

Info

Publication number
DE69329824D1
DE69329824D1 DE69329824T DE69329824T DE69329824D1 DE 69329824 D1 DE69329824 D1 DE 69329824D1 DE 69329824 T DE69329824 T DE 69329824T DE 69329824 T DE69329824 T DE 69329824T DE 69329824 D1 DE69329824 D1 DE 69329824D1
Authority
DE
Germany
Prior art keywords
amplification
detection
nucleic acids
certain nucleic
exonucleolytic activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69329824T
Other languages
English (en)
Other versions
DE69329824T2 (de
Inventor
J Carrinno
Uwe Spies
A Rinehardt
K Pabich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69329824D1 publication Critical patent/DE69329824D1/de
Publication of DE69329824T2 publication Critical patent/DE69329824T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6862—Ligase chain reaction [LCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69329824T 1992-08-03 1993-07-21 Nachweis und amplifikation bestimmter nukleinsäuren mittels exonukleolytischer aktivität Expired - Fee Related DE69329824T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92540292A 1992-08-03 1992-08-03
PCT/US1993/006931 WO1994003636A1 (en) 1992-08-03 1993-07-21 Detecting and amplifying target nucleic acids using exonucleolytic activity

Publications (2)

Publication Number Publication Date
DE69329824D1 true DE69329824D1 (de) 2001-02-08
DE69329824T2 DE69329824T2 (de) 2001-08-09

Family

ID=25451687

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69329824T Expired - Fee Related DE69329824T2 (de) 1992-08-03 1993-07-21 Nachweis und amplifikation bestimmter nukleinsäuren mittels exonukleolytischer aktivität

Country Status (7)

Country Link
EP (1) EP0654093B1 (de)
JP (1) JP3516953B2 (de)
AU (1) AU4687393A (de)
CA (1) CA2140331C (de)
DE (1) DE69329824T2 (de)
ES (1) ES2154648T3 (de)
WO (1) WO1994003636A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593840A (en) * 1993-01-27 1997-01-14 Oncor, Inc. Amplification of nucleic acid sequences
US5888731A (en) * 1995-08-30 1999-03-30 Visible Genetics Inc. Method for identification of mutations using ligation of multiple oligonucleotide probes
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
EP2369007B1 (de) 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Erkennung von Nukleinsäuresequenz-Unterschieden mittels der gleichzeitigen Ligaseerkennungs- und Polymerasekettenreaktion
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
US6511810B2 (en) * 2000-07-03 2003-01-28 Applera Corporation Polynucleotide sequence assay
ATE431407T1 (de) * 2002-01-11 2009-05-15 Biospring Ges Fuer Biotechnolo Verfahren zur herstellung von dna

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU634969B2 (en) * 1988-06-24 1993-03-11 Amgen, Inc. Method and reagents for detecting nucleic acid sequences
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
ES2089038T3 (es) * 1990-01-26 1996-10-01 Abbott Lab Procedimiento mejorado para amplificar acidos nucleicos blanco aplicable para la reaccion en cadena de polimerasa y ligasa.
EP0528882B1 (de) * 1990-05-03 2007-10-10 Cornell Research Foundation, Inc. Ein system der dna amplifikation zur detektion genetischer erkrankungen durch eine thermostabile ligase
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
CA2136764A1 (en) * 1992-05-29 1993-12-09 Ronald L. Marshall Ligase chain reaction starting with rna sequences

Also Published As

Publication number Publication date
AU4687393A (en) 1994-03-03
ES2154648T3 (es) 2001-04-16
CA2140331A1 (en) 1994-02-17
EP0654093A4 (de) 1998-01-07
JPH08501212A (ja) 1996-02-13
CA2140331C (en) 2000-01-18
WO1994003636A1 (en) 1994-02-17
JP3516953B2 (ja) 2004-04-05
EP0654093B1 (de) 2001-01-03
DE69329824T2 (de) 2001-08-09
EP0654093A1 (de) 1995-05-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee