FR2582648B1 - Intermediaires carbacycline optiquement actifs et procedes de leur preparation - Google Patents

Intermediaires carbacycline optiquement actifs et procedes de leur preparation

Info

Publication number
FR2582648B1
FR2582648B1 FR868607990A FR8607990A FR2582648B1 FR 2582648 B1 FR2582648 B1 FR 2582648B1 FR 868607990 A FR868607990 A FR 868607990A FR 8607990 A FR8607990 A FR 8607990A FR 2582648 B1 FR2582648 B1 FR 2582648B1
Authority
FR
France
Prior art keywords
carbacycline
intermediates
processes
preparation
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR868607990A
Other languages
English (en)
Other versions
FR2582648A1 (fr
Inventor
Kenji Mori
Masahiro Tsuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Publication of FR2582648A1 publication Critical patent/FR2582648A1/fr
Application granted granted Critical
Publication of FR2582648B1 publication Critical patent/FR2582648B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/165—Yeast isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C12N1/185—Saccharomyces isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/84—Pichia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR868607990A 1985-06-04 1986-06-03 Intermediaires carbacycline optiquement actifs et procedes de leur preparation Expired - Lifetime FR2582648B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60119807A JPS61280294A (ja) 1985-06-04 1985-06-04 光学活性カルバサイクリン中間体の製造方法

Publications (2)

Publication Number Publication Date
FR2582648A1 FR2582648A1 (fr) 1986-12-05
FR2582648B1 true FR2582648B1 (fr) 1990-03-02

Family

ID=14770710

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868607990A Expired - Lifetime FR2582648B1 (fr) 1985-06-04 1986-06-03 Intermediaires carbacycline optiquement actifs et procedes de leur preparation

Country Status (5)

Country Link
US (2) US4814468A (fr)
JP (1) JPS61280294A (fr)
DE (1) DE3618538C2 (fr)
FR (1) FR2582648B1 (fr)
GB (1) GB2178423B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280294A (ja) * 1985-06-04 1986-12-10 Nisshin Flour Milling Co Ltd 光学活性カルバサイクリン中間体の製造方法
DE3638760A1 (de) * 1986-11-13 1988-05-26 Schering Ag Verfahren zur herstellung von optisch aktiven bicyclo(3.3.0)octandioncarbonsaeureestern
DE3638759A1 (de) * 1986-11-13 1988-06-09 Schering Ag Stereospezifische ketoreduktion von bicyclooctandion-carbonsaeureestern durch mikroorganismen
DE3638762A1 (de) * 1986-11-13 1988-05-26 Schering Ag Racematspaltung von 7(alpha)-acyloxy-6ss-hydroxy-methyl-2-oxabicyclo (3.3.0)octan-3-onen durch stereospezifische enzymatische acylat-hydrolyse
DE3638758A1 (de) * 1986-11-13 1988-05-26 Schering Ag Racematspaltung von 3-acyloxy-bicyclo(3.3.0)octan-7-on-2- carbonsaeureestern durch stereospezifische enzymatische oder mikrobiologische acylat-hydrolyse
DE3708536A1 (de) * 1987-03-13 1988-09-22 Schering Ag Neues verfahren zur antipodentrennung von bicyclo (3.3.0) octan-3,7-dion-2-carbonsaeureestern und ihrer monoketale
US5237192A (en) * 1988-10-12 1993-08-17 Mitsubishi Denki Kabushiki Kaisha MESFET semiconductor device having a T-shaped gate electrode
US5106736A (en) * 1991-04-23 1992-04-21 E.R. Squibb & Sons, Inc. Enzymatic process for enantiomer-specific perparation of mercapto alkanoic acid compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5495552A (en) * 1978-01-06 1979-07-28 Sankyo Co Ltd Prostacyline derivative and its preparation
GB2013661B (en) * 1978-01-26 1982-11-10 Erba Farmitalia 9-deoxy-9 -methylene isosteres of pgi2
IT7819616A0 (it) * 1978-01-26 1978-01-26 Erba Carlo Spa 9-deossi-9a-metilene-isosteri della pgi 2.
EP0101076B1 (fr) * 1982-08-13 1989-01-04 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Procédé de préparation d'oxazolidinones optiquement actives
US4659671A (en) * 1983-07-01 1987-04-21 Massachusetts Institute Of Technology Enzymatic separation of racemic mixtures of hydroxy compounds
EP0130752B1 (fr) * 1983-07-04 1991-02-27 Mitsubishi Rayon Co., Ltd. Procédé de préparation d'acides carboxyliques optiquement actifs et de leurs esters antipodes
US4668628A (en) * 1985-04-01 1987-05-26 Stauffer Chemical Company Resolution of racemic mixtures of aliphatic acid esters
JPS61280294A (ja) * 1985-06-04 1986-12-10 Nisshin Flour Milling Co Ltd 光学活性カルバサイクリン中間体の製造方法

Also Published As

Publication number Publication date
DE3618538A1 (de) 1986-12-18
FR2582648A1 (fr) 1986-12-05
GB2178423B (en) 1989-04-26
GB2178423A (en) 1987-02-11
JPH0567280B2 (fr) 1993-09-24
US4814468A (en) 1989-03-21
DE3618538C2 (de) 1996-02-29
JPS61280294A (ja) 1986-12-10
GB8613596D0 (en) 1986-07-09
US4885246A (en) 1989-12-05

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