DE69329135D1 - Verfahren und Vorrichtung zur magnetischen Abscheidung - Google Patents

Verfahren und Vorrichtung zur magnetischen Abscheidung

Info

Publication number
DE69329135D1
DE69329135D1 DE69329135T DE69329135T DE69329135D1 DE 69329135 D1 DE69329135 D1 DE 69329135D1 DE 69329135 T DE69329135 T DE 69329135T DE 69329135 T DE69329135 T DE 69329135T DE 69329135 D1 DE69329135 D1 DE 69329135D1
Authority
DE
Germany
Prior art keywords
systems
deposition method
annular
particles
magnetic deposition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69329135T
Other languages
English (en)
Other versions
DE69329135T2 (de
Inventor
Roland Paul Howe
Michael Alan Reeve
Daniel Bischof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare UK Ltd
Original Assignee
Amersham Pharmacia Biotech UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Pharmacia Biotech UK Ltd filed Critical Amersham Pharmacia Biotech UK Ltd
Publication of DE69329135D1 publication Critical patent/DE69329135D1/de
Application granted granted Critical
Publication of DE69329135T2 publication Critical patent/DE69329135T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0335—Component parts; Auxiliary operations characterised by the magnetic circuit using coils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
DE69329135T 1992-09-24 1993-09-17 Verfahren und Vorrichtung zur magnetischen Abscheidung Expired - Fee Related DE69329135T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92308727 1992-09-24

Publications (2)

Publication Number Publication Date
DE69329135D1 true DE69329135D1 (de) 2000-09-07
DE69329135T2 DE69329135T2 (de) 2001-01-11

Family

ID=8211498

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69329135T Expired - Fee Related DE69329135T2 (de) 1992-09-24 1993-09-17 Verfahren und Vorrichtung zur magnetischen Abscheidung

Country Status (5)

Country Link
US (1) US5458785A (de)
JP (1) JPH06198214A (de)
AT (1) ATE195081T1 (de)
CA (1) CA2106640A1 (de)
DE (1) DE69329135T2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897783A (en) * 1992-09-24 1999-04-27 Amersham International Plc Magnetic separation method
US5956204A (en) * 1995-02-13 1999-09-21 Seagate Technology, Inc. Magnetic disc drive having magnetic particle trap for hydrodynamic bearing
US5969903A (en) * 1995-02-13 1999-10-19 Seagate Technology, Inc. Magnetic particle trap for hydrodynamic bearing
US5888835A (en) * 1996-05-10 1999-03-30 Chiron Diagnostics Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US6036857A (en) * 1998-02-20 2000-03-14 Florida State University Research Foundation, Inc. Apparatus for continuous magnetic separation of components from a mixture
EP1671703A3 (de) * 1998-03-19 2006-07-05 Precision System Science Co., Ltd. Verfahren zur Herstellung von Substanzen in Trägern
US6055126A (en) 1998-07-06 2000-04-25 Seagate Technology, Inc. Disc drive having hydrodynamic labyrinth seal and magnet shield
US6776174B2 (en) * 1998-08-21 2004-08-17 Paul E. Nisson Apparatus for washing magnetic particles
US20020012916A1 (en) * 1998-10-14 2002-01-31 Gundling Gerard J A method of reducing contamination in an essay vessel
US6413780B1 (en) * 1998-10-14 2002-07-02 Abbott Laboratories Structure and method for performing a determination of an item of interest in a sample
US5973138A (en) 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
US6193892B1 (en) 1999-03-03 2001-02-27 Promega Corporation Magnetic separation assembly and method
US6614337B1 (en) * 1999-06-29 2003-09-02 Stanley D. Winnard Magnetic holding device
DE60026641T2 (de) 1999-07-15 2007-01-25 Qiagen Gmbh Verfahren zur Trennung von teilchenförmigen Substraten aus einer Lösung indem man den Teilchenverlust minimiert
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
US6954128B2 (en) * 2001-11-30 2005-10-11 The Regents Of The University Of California High performance hybrid magnetic structure for biotechnology applications
US7148778B2 (en) * 2001-11-30 2006-12-12 The Regents Of The University Of California High performance hybrid magnetic structure for biotechnology applications
AU2003226075B2 (en) 2002-04-12 2008-09-25 Instrumentation Laboratory Company Immunoassay probe
EP2500076B1 (de) * 2002-04-26 2017-11-01 Abbott Laboratories Struktur und Verfahren zur Handhabung magnetischer Partikel in biologischen Tests
US7119645B2 (en) * 2003-02-25 2006-10-10 The University Of North Carolina Methods and systems for controlling motion of and tracking a mechanically unattached probe
FI20031635A0 (fi) * 2003-11-11 2003-11-11 Thermo Electron Oy Partikkelien erotusväline
US20050266394A1 (en) * 2003-12-24 2005-12-01 Massachusette Institute Of Technology Magnetophoretic cell clarification
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
US8152305B2 (en) * 2004-07-16 2012-04-10 The University Of North Carolina At Chapel Hill Methods, systems, and computer program products for full spectrum projection
EP1842596B1 (de) * 2004-12-22 2019-01-23 Giamag Technologies AS Stofftrennungsvorrichtung zur erzeugung eines magnetfeldes mit hohem gradienten
US8490469B2 (en) * 2007-02-22 2013-07-23 The University Of North Carolina Methods and systems for multiforce high throughput screening
US9199247B2 (en) * 2007-05-29 2015-12-01 Invitrogen Dynal As Magnetic separation rack
GB0724404D0 (en) * 2007-05-29 2008-01-30 Invitrogen Dynal As A sample vessel retaining portion
US7883265B2 (en) * 2007-06-01 2011-02-08 Applied Biosystems, Llc Devices, systems, and methods for preparing emulsions
US8440469B2 (en) * 2007-06-18 2013-05-14 Morpho Detection, Inc. System and method for increasing spectroscopic signal
US20100282685A1 (en) * 2007-07-25 2010-11-11 Halaka Folim G Magnetic mixer
EP2030689B1 (de) * 2007-08-31 2013-02-13 Tecan Trading AG Mikroplatten-Träger mit Magneten
US20100077843A1 (en) * 2008-03-31 2010-04-01 Doraisamy Loganathan Substance identification apparatus and methods of using
AU2009257644B2 (en) 2008-06-09 2015-05-07 Qiagen Gaithersburg, Inc. Magnetic microplate assembly
JP5511949B2 (ja) 2009-06-25 2014-06-04 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 体液レオロジーを評価するための、作動され表面に付着したポストを使用するための方法及びシステム
US8083069B2 (en) * 2009-07-31 2011-12-27 General Electric Company High throughput magnetic isolation technique and device for biological materials
CN104395736B (zh) * 2012-06-29 2018-12-11 皇家飞利浦有限公司 对结合的磁性粒子和未结合的磁性粒子进行处理
EP2926115B1 (de) 2012-11-30 2021-05-26 The University of North Carolina At Chapel Hill Verfahren und systeme zur bestimmung der physikalischer eigenschaften einer probe in einer tragbaren point-of-care-diagnosevorrichtung
WO2017158425A1 (en) 2016-03-18 2017-09-21 Andrew Alliance S.A. Methods and apparatus for bead manipulation in a tip of a liquid handler
US20190270084A1 (en) * 2018-03-03 2019-09-05 Yuchen Zhou Methods and apparatus to separate biological entities

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3981776A (en) * 1967-02-16 1976-09-21 Rolf Saxholm Magnetically responsive, biologically active substance and associated methods and apparatus
CH663476A5 (fr) * 1985-07-08 1987-12-15 Serono Diagnostics Ltd Enceinte pour le dosage d'anticorps ou d'antigenes dans un liquide biologique.
NO168811C (no) * 1989-05-31 1992-04-08 Dynal As Separasjonsanordning for separering av magnetiserbare partikler
DE3925093C2 (de) * 1989-07-28 1995-03-30 Roland Dipl Phys Hartig Vorrichtung zur Trennung von an magnetischen Partikeln (Beads) gebundenem biologischem Material in einem Magnetfeld
GB8927744D0 (en) * 1989-12-07 1990-02-07 Diatec A S Process and apparatus
GB9003253D0 (en) * 1990-02-13 1990-04-11 Amersham Int Plc Precipitating polymers
WO1992005443A1 (en) * 1990-09-15 1992-04-02 Medical Research Council Reagent separation
EP0479448A3 (en) * 1990-10-02 1992-12-23 Beckman Instruments, Inc. Magnetic separation device

Also Published As

Publication number Publication date
CA2106640A1 (en) 1994-03-25
US5458785A (en) 1995-10-17
JPH06198214A (ja) 1994-07-19
ATE195081T1 (de) 2000-08-15
DE69329135T2 (de) 2001-01-11

Similar Documents

Publication Publication Date Title
DE69329135T2 (de) Verfahren und Vorrichtung zur magnetischen Abscheidung
DE69515675T2 (de) Verfahren zum Einfangen von einem Ligand aus einer Flüssigkeit und Vorrichtung zur dessen Ausführung
DE68911628T2 (de) Verfahren zur automatischen Bearbeitung von magnetischen Festphasen-Reagenzien.
DE3677002D1 (de) Verfahren und vorrichtung zur regelung geladener teilchen.
ATE300046T1 (de) Vorrichtung und verfahren zur überführung magnetischer partikeln
ATE25595T1 (de) Magnetisches flotationsverfahren.
DE69003175T2 (de) Verfahren und Vorrichtung zur Plasmaaussenabscheidung von hydroxylionenfreier Silika.
ATE297255T1 (de) System zur separation von magnetisch anziehbaren partikeln
DE58903943D1 (de) Verfahren zur trennung von dampffoermigen schwermetallverbindungen von einem traegergas und vorrichtung zur durchfuehrung des verfahrens.
DE69004485T2 (de) Verfahren und Vorrichtung zur Abtrennung von nichtmetallischen Verunreinigungen aus Flüssigmetallen.
DE69318396D1 (de) Verfahren und vorrichtung zur entfernung suspendierter feinpartikel aus gasen
DE3764390D1 (de) Verfahren zur kontinuierlichen separation magnetisierbarer partikel und einrichtung zu seiner durchfuehrung.
DE3381146D1 (de) Verfahren und vorrichtung zur spruehfraktionierung von teilchen in fluessiger suspension.
DE68911158D1 (de) Verfahren zur Abtrennung und Gewinnung von Erythrit aus einem dieses enthaltenden Kulturmedium.
DE60324959D1 (de) Vorrichtung und verfahren zur trennung von erzeugten partikeln als suspension in einem nicht superkritischen fluid
DE3779463D1 (de) Verfahren und vorrichtung zur agglomerierung von elektrisch ungleichfoermig aufgeladenen, in gasstroemen suspendierten festen oder fluessigen partikeln.
DE69025837T2 (de) Verfahren zur Entfernung von feinkörnigen Teilchen aus Fluoroharzgegenständen
ATE148492T1 (de) Verfahren zum entfernen von quecksilber
DE69020469T2 (de) Verfahren und Vorrichtung zur Abtrennung von nichtmetallischen Verunreinigungen aus Flüssigmetallen.
DE69418515D1 (de) Vorrichtung zur Trennung von fluidisierfähigen Materialien aus nichtfluidisierfähigen Materialien
AT383512B (de) Verfahren und vorrichtung zur abtrennung von sand von botanischen feinteilchen
DE363119T1 (de) System zur zentrifugalbehandlung grosser mengen an fluessigkeiten und verfahren fuer suspensionszellkulturen.
DE69315935D1 (de) Verfahren und Vorrichtung zur Herstellung von magnetischen metallischen Teilchen
DE69311613D1 (de) Verfahren und Vorrichtung zur Reaktion von Partikeln
DE3787017T2 (de) Verfahren und Vorrichtung zur Erzeugung von flüssigem Metall von Erzpartikeln.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee