DE69515675T2 - Verfahren zum Einfangen von einem Ligand aus einer Flüssigkeit und Vorrichtung zur dessen Ausführung - Google Patents
Verfahren zum Einfangen von einem Ligand aus einer Flüssigkeit und Vorrichtung zur dessen AusführungInfo
- Publication number
- DE69515675T2 DE69515675T2 DE69515675T DE69515675T DE69515675T2 DE 69515675 T2 DE69515675 T2 DE 69515675T2 DE 69515675 T DE69515675 T DE 69515675T DE 69515675 T DE69515675 T DE 69515675T DE 69515675 T2 DE69515675 T2 DE 69515675T2
- Authority
- DE
- Germany
- Prior art keywords
- pct
- species
- particles
- support
- date nov
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9409348A GB9409348D0 (en) | 1994-05-11 | 1994-05-11 | Methods of capturing species from liquids and assay procedures |
GB9423867A GB9423867D0 (en) | 1994-11-25 | 1994-11-25 | Methods of capturing species from liquids and assay procedures |
PCT/GB1995/001056 WO1995031726A1 (en) | 1994-05-11 | 1995-05-10 | Methods of capturing species from liquids and assay procedures |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69515675D1 DE69515675D1 (de) | 2000-04-20 |
DE69515675T2 true DE69515675T2 (de) | 2000-07-20 |
Family
ID=26304862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69515675T Expired - Lifetime DE69515675T2 (de) | 1994-05-11 | 1995-05-10 | Verfahren zum Einfangen von einem Ligand aus einer Flüssigkeit und Vorrichtung zur dessen Ausführung |
Country Status (9)
Country | Link |
---|---|
US (1) | US5834197A (de) |
EP (1) | EP0775313B1 (de) |
JP (1) | JP3339026B2 (de) |
AT (1) | ATE190727T1 (de) |
AU (1) | AU697863B2 (de) |
CA (1) | CA2189958C (de) |
DE (1) | DE69515675T2 (de) |
NZ (1) | NZ285139A (de) |
WO (1) | WO1995031726A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU690619B2 (en) * | 1993-12-21 | 1998-04-30 | Genera Technologies Limited | Filtration method and apparatus |
US5888748A (en) * | 1995-07-13 | 1999-03-30 | Immucell Corporation | Methods and articles of manufacture for the detection of cryptosporidium occysts |
US6159689A (en) * | 1995-11-10 | 2000-12-12 | Genera Technologies Limited | Methods of capture and assay procedures |
GB9523045D0 (en) * | 1995-11-10 | 1996-01-10 | Genera Tech Ltd | Methods of capture and asssy procedures |
FR2748569B1 (fr) * | 1996-05-07 | 1998-08-07 | Biocom Sa | Procede et installation de separation de particules magnetiques dans un fluide pour l'analyse biologique, et application dudit procede |
FR2801677B1 (fr) * | 1999-11-30 | 2003-04-25 | Ulp Ct D Analyses Et De Rech S | Procede d'analyse d'un echantillon pour la presence eventuelle de legionelles comprenant une etape d'immunocapture |
US6672458B2 (en) * | 2000-05-19 | 2004-01-06 | Becton, Dickinson And Company | System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample |
US6649419B1 (en) | 2000-11-28 | 2003-11-18 | Large Scale Proteomics Corp. | Method and apparatus for protein manipulation |
CA2483694C (en) | 2002-05-17 | 2016-04-19 | Becton, Dickinson And Company | Automated system for isolating, amplifying and detecting a target nucleic acid sequence |
US7601491B2 (en) | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
US20070003975A1 (en) * | 2003-05-02 | 2007-01-04 | Canon Kabushiki Kaisha | Structured construct and producing method therefor |
DE10331254B4 (de) * | 2003-07-10 | 2006-05-04 | Chemagen Biopolymer-Technologie Aktiengesellschaft | Vorrichtung und Verfahren zum Abtrennen von magnetischen oder magnetisierbaren Partikeln aus einer Flüssigkeit |
US8211386B2 (en) | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
JP2008532551A (ja) * | 2005-03-17 | 2008-08-21 | ファイジェニックス, エルエルシー | 生存可能なレジオネラ属の迅速な検出および定量 |
US7901932B2 (en) * | 2005-03-17 | 2011-03-08 | Phigenics, Llc | Methods and compositions for rapidly detecting and quantifying viable Legionella |
FI20051248L (fi) | 2005-12-02 | 2007-06-03 | Bio Nobile Oy | Biologisten komponenttien rikastusyksikkö ja rikastusmenetelmä |
US20070193934A1 (en) * | 2006-01-28 | 2007-08-23 | Shukla Ashok K | Perforated surface for sample preparation |
CA2685229A1 (en) * | 2007-04-26 | 2008-11-06 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Health | Process for isolating microorganisms from samples and system, apparatus and compositions therefor |
US7883265B2 (en) * | 2007-06-01 | 2011-02-08 | Applied Biosystems, Llc | Devices, systems, and methods for preparing emulsions |
EP2568050A3 (de) * | 2007-08-01 | 2013-04-24 | Hitachi Chemical Co., Ltd. | Nachweis von Krankheitserregern in grossvolumigen Partikelproben |
CN101657262B (zh) * | 2008-02-22 | 2011-04-20 | 江苏圣奥化学科技有限公司 | 从固-液混合物中回收固体物料的磁分离装置及反应系统 |
US20100018674A1 (en) * | 2008-07-22 | 2010-01-28 | Donald John Enzinna | Reservoir with moveable partition for quick recovery |
EP2336349B1 (de) | 2008-09-26 | 2016-01-06 | Biótica, Bioquímica Analítica, S.L. | Schnellverfahren zum nachweis von mikroorganismen mit magnetteilchen |
US9399217B2 (en) | 2010-10-04 | 2016-07-26 | Genapsys, Inc. | Chamber free nanoreactor system |
US9184099B2 (en) | 2010-10-04 | 2015-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Biosensor devices, systems and methods therefor |
US9187783B2 (en) | 2010-10-04 | 2015-11-17 | Genapsys, Inc. | Systems and methods for automated reusable parallel biological reactions |
GB201100515D0 (en) | 2011-01-13 | 2011-02-23 | Matrix Microscience Ltd | Methods of capturing bindable targets from liquids |
US8585973B2 (en) | 2011-05-27 | 2013-11-19 | The Board Of Trustees Of The Leland Stanford Junior University | Nano-sensor array |
US9926596B2 (en) | 2011-05-27 | 2018-03-27 | Genapsys, Inc. | Systems and methods for genetic and biological analysis |
CN104105797B (zh) | 2011-12-01 | 2016-08-31 | 吉纳普赛斯股份有限公司 | 用于高效电子测序与检测的系统和方法 |
GB201202762D0 (en) | 2012-02-17 | 2012-04-04 | Autology Health Ltd | High efficiency cell capture |
US10221442B2 (en) | 2012-08-14 | 2019-03-05 | 10X Genomics, Inc. | Compositions and methods for sample processing |
MX364957B (es) | 2012-08-14 | 2019-05-15 | 10X Genomics Inc | Composiciones y metodos para microcapsulas. |
US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US20150376609A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Methods of Analyzing Nucleic Acids from Individual Cells or Cell Populations |
US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10400280B2 (en) | 2012-08-14 | 2019-09-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
CA2894694C (en) | 2012-12-14 | 2023-04-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
CA2900481A1 (en) | 2013-02-08 | 2014-08-14 | 10X Genomics, Inc. | Polynucleotide barcode generation |
CN105051214B (zh) | 2013-03-15 | 2018-12-28 | 吉纳普赛斯股份有限公司 | 用于生物分析的系统和方法 |
US10395758B2 (en) | 2013-08-30 | 2019-08-27 | 10X Genomics, Inc. | Sequencing methods |
WO2015089238A1 (en) | 2013-12-11 | 2015-06-18 | Genapsys, Inc. | Systems and methods for biological analysis and computation |
US9824068B2 (en) | 2013-12-16 | 2017-11-21 | 10X Genomics, Inc. | Methods and apparatus for sorting data |
AU2015243445B2 (en) | 2014-04-10 | 2020-05-28 | 10X Genomics, Inc. | Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same |
EP3556864B1 (de) | 2014-04-18 | 2020-12-09 | Genapsys, Inc. | Verfahren und systeme zur nukleinsäureamplifikation |
JP2017526046A (ja) | 2014-06-26 | 2017-09-07 | 10エックス ゲノミクス,インコーポレイテッド | 核酸配列アセンブルのプロセス及びシステム |
US20160122817A1 (en) | 2014-10-29 | 2016-05-05 | 10X Genomics, Inc. | Methods and compositions for targeted nucleic acid sequencing |
US9975122B2 (en) | 2014-11-05 | 2018-05-22 | 10X Genomics, Inc. | Instrument systems for integrated sample processing |
SG11201705615UA (en) | 2015-01-12 | 2017-08-30 | 10X Genomics Inc | Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same |
KR20170106979A (ko) | 2015-01-13 | 2017-09-22 | 10엑스 제노믹스, 인크. | 구조 변이 및 위상 조정 정보를 시각화하기 위한 시스템 및 방법 |
US10854315B2 (en) | 2015-02-09 | 2020-12-01 | 10X Genomics, Inc. | Systems and methods for determining structural variation and phasing using variant call data |
EP3262407B1 (de) | 2015-02-24 | 2023-08-30 | 10X Genomics, Inc. | Partitionsverarbeitungsverfahren und -systeme |
EP3262188B1 (de) | 2015-02-24 | 2021-05-05 | 10X Genomics, Inc. | Verfahren zur sequenzierung von nukleinsäuren in gesteuertem ausmass |
SG11201804086VA (en) | 2015-12-04 | 2018-06-28 | 10X Genomics Inc | Methods and compositions for nucleic acid analysis |
SG11201806757XA (en) | 2016-02-11 | 2018-09-27 | 10X Genomics Inc | Systems, methods, and media for de novo assembly of whole genome sequence data |
WO2017197338A1 (en) | 2016-05-13 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic systems and methods of use |
EP3488017A4 (de) | 2016-07-20 | 2020-02-26 | Genapsys Inc. | Systeme und verfahren zur nukleinsäuresequenzierung |
US10011872B1 (en) | 2016-12-22 | 2018-07-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
EP4029939B1 (de) | 2017-01-30 | 2023-06-28 | 10X Genomics, Inc. | Verfahren und systeme für eine einzelzellbarcodierung auf tröpfchenbasis |
EP3625715A4 (de) | 2017-05-19 | 2021-03-17 | 10X Genomics, Inc. | Systeme und verfahren zur analyse von datensätzen |
US10400235B2 (en) | 2017-05-26 | 2019-09-03 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
CN116064732A (zh) | 2017-05-26 | 2023-05-05 | 10X基因组学有限公司 | 转座酶可接近性染色质的单细胞分析 |
CN111566224A (zh) | 2017-09-21 | 2020-08-21 | 吉纳普赛斯股份有限公司 | 用于核酸测序的系统和方法 |
SG11201913654QA (en) | 2017-11-15 | 2020-01-30 | 10X Genomics Inc | Functionalized gel beads |
US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
SG11202009889VA (en) | 2018-04-06 | 2020-11-27 | 10X Genomics Inc | Systems and methods for quality control in single cell processing |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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US3917538A (en) * | 1973-01-17 | 1975-11-04 | Ferrofluidics Corp | Ferrofluid compositions and process of making same |
US4157323A (en) * | 1976-06-09 | 1979-06-05 | California Institute Of Technology | Metal containing polymeric functional microspheres |
IL65131A0 (en) * | 1982-02-28 | 1982-04-30 | Yeda Res & Dev | Process for the production of agarose-polyaldehyde beads and their biological applications |
US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
DE3444939A1 (de) * | 1984-12-08 | 1986-06-12 | Bayer Ag, 5090 Leverkusen | Magnetische microspheres |
AU601386B2 (en) * | 1985-12-20 | 1990-09-13 | Syntex (U.S.A.) Inc. | Particle separation method |
US5385707A (en) * | 1988-12-28 | 1995-01-31 | Stefan Miltenyi | Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same |
WO1994011078A1 (en) * | 1992-11-16 | 1994-05-26 | Immunivest Corporation | Magnetic immobilization and manipulation of biological entities |
US5610274A (en) * | 1991-11-20 | 1997-03-11 | Cpg, Inc. | Production and use of magnetic porous inorganic materials |
WO1993016383A1 (en) * | 1992-02-08 | 1993-08-19 | Genera Technologies Limited | Methods of analysis |
-
1995
- 1995-05-10 DE DE69515675T patent/DE69515675T2/de not_active Expired - Lifetime
- 1995-05-10 NZ NZ285139A patent/NZ285139A/xx not_active IP Right Cessation
- 1995-05-10 CA CA002189958A patent/CA2189958C/en not_active Expired - Lifetime
- 1995-05-10 AT AT95918081T patent/ATE190727T1/de not_active IP Right Cessation
- 1995-05-10 US US08/737,296 patent/US5834197A/en not_active Expired - Lifetime
- 1995-05-10 JP JP52943595A patent/JP3339026B2/ja not_active Expired - Lifetime
- 1995-05-10 EP EP95918081A patent/EP0775313B1/de not_active Expired - Lifetime
- 1995-05-10 WO PCT/GB1995/001056 patent/WO1995031726A1/en active IP Right Grant
- 1995-05-10 AU AU24146/95A patent/AU697863B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU2414695A (en) | 1995-12-05 |
CA2189958C (en) | 2005-04-19 |
WO1995031726A1 (en) | 1995-11-23 |
NZ285139A (en) | 1998-10-28 |
CA2189958A1 (en) | 1995-11-23 |
EP0775313B1 (de) | 2000-03-15 |
EP0775313A1 (de) | 1997-05-28 |
ATE190727T1 (de) | 2000-04-15 |
DE69515675D1 (de) | 2000-04-20 |
US5834197A (en) | 1998-11-10 |
JP3339026B2 (ja) | 2002-10-28 |
AU697863B2 (en) | 1998-10-22 |
JPH10500213A (ja) | 1998-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: GENERA TECHNOLOGIES LTD., NEWMARKET, SUFFOLK, GB |
|
8364 | No opposition during term of opposition |