DE69328091D1 - Bindungspeptide zur interaktion mit wachstumsfaktoren als liganden des rezeptors des epidermiswachstumsfactor und des erbb-2-rezeptor - Google Patents
Bindungspeptide zur interaktion mit wachstumsfaktoren als liganden des rezeptors des epidermiswachstumsfactor und des erbb-2-rezeptorInfo
- Publication number
- DE69328091D1 DE69328091D1 DE69328091T DE69328091T DE69328091D1 DE 69328091 D1 DE69328091 D1 DE 69328091D1 DE 69328091 T DE69328091 T DE 69328091T DE 69328091 T DE69328091 T DE 69328091T DE 69328091 D1 DE69328091 D1 DE 69328091D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- erbb
- ligands
- interaction
- growth factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/485—Epidermal growth factor [EGF] (urogastrone)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Endocrinology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87578892A | 1992-04-29 | 1992-04-29 | |
US91798892A | 1992-07-24 | 1992-07-24 | |
PCT/US1993/004055 WO1993022339A1 (en) | 1992-04-29 | 1993-04-29 | BINDING PEPTIDES WHICH INTERACT WITH LIGAND GROWTH FACTORS OF THE EPIDERMAL GROWTH FACTOR RECEPTOR AND erbB-2-RECEPTOR |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69328091D1 true DE69328091D1 (de) | 2000-04-20 |
DE69328091T2 DE69328091T2 (de) | 2000-10-12 |
Family
ID=27128384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69328091T Expired - Fee Related DE69328091T2 (de) | 1992-04-29 | 1993-04-29 | Bindungspeptide zur interaktion mit wachstumsfaktoren als liganden des rezeptors des epidermiswachstumsfactor und des erbb-2-rezeptor |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0641358B1 (de) |
JP (1) | JPH08502241A (de) |
AT (1) | ATE190626T1 (de) |
AU (1) | AU676476B2 (de) |
CA (1) | CA2134544A1 (de) |
DE (1) | DE69328091T2 (de) |
NZ (1) | NZ252486A (de) |
WO (1) | WO1993022339A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
US7319019B1 (en) | 1991-04-10 | 2008-01-15 | Acorda Therapeutics, Inc. | Glial mitogenic factors lacking an N-terminal signal sequence |
US7285531B1 (en) | 1991-04-10 | 2007-10-23 | Acorda Therapeutics, Inc. | Method for prophylaxis or treatment of a nervous system, pathophysiological condition involving a glial growth factor sensitive cell by administration of a glial growth factor |
US7135456B1 (en) | 1991-04-10 | 2006-11-14 | Acorda Therapeutics, Inc. | Glial mitogenic factors, their preparation and use |
US7094749B1 (en) | 1991-04-10 | 2006-08-22 | Acorda Therapeutics, Inc. | Glial mitogenic factors, their preparation and use |
IL101943A0 (en) * | 1991-05-24 | 1992-12-30 | Genentech Inc | Structure,production and use of heregulin |
US5834229A (en) * | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
DE69535707T2 (de) * | 1994-03-14 | 2009-05-07 | New York University | Methoden zur behandlung oder diagnose von krankheiten oder zuständen, die mit einer abnormalen signalübertragung assoziiert sind |
US5770567A (en) * | 1994-11-14 | 1998-06-23 | Genentech, Inc. | Sensory and motor neuron derived factor (SMDF) |
US6251866B1 (en) | 1997-08-05 | 2001-06-26 | Watson Laboratories, Inc. | Conjugates targeted to the interleukin-2 receptor |
EP1236474A1 (de) * | 2001-02-26 | 2002-09-04 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Negative Regulierung des EGF Rezeptors durch Mig-6 |
WO2002087618A1 (fr) * | 2001-04-27 | 2002-11-07 | Takeda Chemical Industries, Ltd. | Methode de prevention et de traitement du cancer |
US20040138160A1 (en) * | 2001-04-27 | 2004-07-15 | Kenichiro Naito | Preventive/therapeutic method for cancer |
DE60335609D1 (de) * | 2002-03-08 | 2011-02-17 | Max Planck Gesellschaft | Ür menschlichen krebs |
WO2011097633A2 (en) * | 2010-02-08 | 2011-08-11 | Board Of Regents, The University Of Texas System | Egf receptor mimicking peptides |
PL219845B1 (pl) | 2011-01-05 | 2015-07-31 | Adamed Spółka Z Ograniczoną Odpowiedzialnością | Przeciwnowotworowe białko fuzyjne |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4933294A (en) * | 1984-01-30 | 1990-06-12 | Icrf Patents Limited | Method of detecting truncated epidermal growth factor receptors |
US4859609A (en) * | 1986-04-30 | 1989-08-22 | Genentech, Inc. | Novel receptors for efficient determination of ligands and their antagonists or agonists |
US4774321A (en) * | 1986-12-01 | 1988-09-27 | Massachusetts Institute Of Technology | DP100 EGF and insulin-binding protein from Drosophila cells |
AU667026B2 (en) * | 1990-05-25 | 1996-03-07 | Georgetown University | Growth factor which inhibits the growth of cells overexpressing the human oncogene erbB-2 |
-
1993
- 1993-04-29 CA CA002134544A patent/CA2134544A1/en not_active Abandoned
- 1993-04-29 NZ NZ252486A patent/NZ252486A/xx unknown
- 1993-04-29 AT AT93910919T patent/ATE190626T1/de not_active IP Right Cessation
- 1993-04-29 JP JP5519523A patent/JPH08502241A/ja active Pending
- 1993-04-29 EP EP93910919A patent/EP0641358B1/de not_active Expired - Lifetime
- 1993-04-29 AU AU42244/93A patent/AU676476B2/en not_active Ceased
- 1993-04-29 DE DE69328091T patent/DE69328091T2/de not_active Expired - Fee Related
- 1993-04-29 WO PCT/US1993/004055 patent/WO1993022339A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ATE190626T1 (de) | 2000-04-15 |
CA2134544A1 (en) | 1993-11-11 |
EP0641358A4 (de) | 1997-06-25 |
WO1993022339A1 (en) | 1993-11-11 |
DE69328091T2 (de) | 2000-10-12 |
AU4224493A (en) | 1993-11-29 |
EP0641358B1 (de) | 2000-03-15 |
NZ252486A (en) | 1997-08-22 |
AU676476B2 (en) | 1997-03-13 |
EP0641358A1 (de) | 1995-03-08 |
JPH08502241A (ja) | 1996-03-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |