DE69327890T2 - Verfahren zur Herstellung von 2-(un)substituierten 4-Alkylimidazolen - Google Patents

Verfahren zur Herstellung von 2-(un)substituierten 4-Alkylimidazolen

Info

Publication number
DE69327890T2
DE69327890T2 DE69327890T DE69327890T DE69327890T2 DE 69327890 T2 DE69327890 T2 DE 69327890T2 DE 69327890 T DE69327890 T DE 69327890T DE 69327890 T DE69327890 T DE 69327890T DE 69327890 T2 DE69327890 T2 DE 69327890T2
Authority
DE
Germany
Prior art keywords
formula
alkylimidazoles
substituted
preparation
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69327890T
Other languages
English (en)
Other versions
DE69327890D1 (de
Inventor
Susumu Takada
Makoto Adachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE69327890D1 publication Critical patent/DE69327890D1/de
Application granted granted Critical
Publication of DE69327890T2 publication Critical patent/DE69327890T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
DE69327890T 1992-08-18 1993-08-13 Verfahren zur Herstellung von 2-(un)substituierten 4-Alkylimidazolen Expired - Fee Related DE69327890T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21907892 1992-08-18

Publications (2)

Publication Number Publication Date
DE69327890D1 DE69327890D1 (de) 2000-03-30
DE69327890T2 true DE69327890T2 (de) 2000-07-20

Family

ID=16729919

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69327890T Expired - Fee Related DE69327890T2 (de) 1992-08-18 1993-08-13 Verfahren zur Herstellung von 2-(un)substituierten 4-Alkylimidazolen

Country Status (15)

Country Link
US (1) US5312927A (de)
EP (1) EP0585014B1 (de)
JP (1) JP3393891B2 (de)
KR (1) KR100244831B1 (de)
CN (1) CN1032690C (de)
AT (1) ATE189890T1 (de)
CA (1) CA2104268C (de)
DE (1) DE69327890T2 (de)
DK (1) DK0585014T3 (de)
ES (1) ES2145033T3 (de)
GR (1) GR3032807T3 (de)
HU (1) HU216973B (de)
PT (1) PT585014E (de)
TW (1) TW240223B (de)
ZA (1) ZA936054B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681956A (en) * 1990-12-28 1997-10-28 Neurogen Corporation 4-aryl substituted piperazinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands
US5712392A (en) * 1990-12-28 1998-01-27 Neurogen Corporation Certain 4-piperidine- and piperazinoalkyl-2-phenyl imidazole derivatives; dopamine receptor subtype specific ligands
US5646279A (en) * 1990-12-28 1997-07-08 Neurogen Corporation Substituted 4-piperazinylmethyl 2-phenylimidazoles; dopamine receptor subtype specific ligands
US5633376A (en) * 1990-12-28 1997-05-27 Neurogen Corporation Certain aminomethyl phenylimidazole derivatives; and 4-aryl substituted piperazinyl and piperidinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype ligands
US5362334A (en) * 1993-12-23 1994-11-08 Macdermid, Incorporated Composition and process for treatment of metallic surfaces
FR2717474B1 (fr) * 1994-03-15 1996-06-21 Hoechst France Procédé de préparation d'acétals du formyl-2 imidazole.
CA2232467A1 (en) * 1997-03-20 1998-09-20 Richard A. Glennon Imidazoles with serotonin receptor binding activity
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
US6166205A (en) * 1998-09-02 2000-12-26 Neurogen Corporation 2-Aryl-4-(1-[4-heteroaryl]piperazin-1-yl)methylimidazoles: dopamine . D.sub4 receptor subtype ligands
US7108834B2 (en) 2004-10-14 2006-09-19 Chuan Pan Huang Device for producing negative ion fragrance
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
SI3289876T1 (sl) 2008-06-16 2023-01-31 University of Tennessee Research Foundation, Spojine za zdravljenje raka
EP3064204A1 (de) * 2010-03-01 2016-09-07 GTx, Inc. Verbindungen zur behandlung von krebs
CN102199126B (zh) * 2010-03-25 2013-06-05 中国石油化工股份有限公司 一种二烷基咪唑的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7017486A (de) * 1969-12-15 1971-06-17
GB2068362B (en) * 1980-01-25 1983-11-16 Kodak Ltd Preparation of imidazoles
DE3018458A1 (de) * 1980-05-14 1982-01-21 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 4-methylimidazolen
YU47834B (sr) * 1989-08-10 1996-01-09 Schering Agrochemical Limited Azolni pesticid
AU1191292A (en) * 1991-02-11 1992-09-07 Schering Agrochemicals Limited Imidazole pesticides

Also Published As

Publication number Publication date
PT585014E (pt) 2000-06-30
US5312927A (en) 1994-05-17
KR100244831B1 (ko) 2000-03-02
DE69327890D1 (de) 2000-03-30
EP0585014A2 (de) 1994-03-02
CA2104268A1 (en) 1994-02-19
EP0585014A3 (de) 1994-12-14
DK0585014T3 (da) 2000-06-05
ATE189890T1 (de) 2000-03-15
CN1091130A (zh) 1994-08-24
HUT65121A (en) 1994-04-28
CN1032690C (zh) 1996-09-04
JP3393891B2 (ja) 2003-04-07
TW240223B (de) 1995-02-11
ES2145033T3 (es) 2000-07-01
CA2104268C (en) 2003-10-28
HU9302360D0 (en) 1993-11-29
HU216973B (hu) 1999-10-28
KR940003938A (ko) 1994-03-14
JPH06116242A (ja) 1994-04-26
ZA936054B (en) 1995-02-03
EP0585014B1 (de) 2000-02-23
GR3032807T3 (en) 2000-06-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee