DE69308009T2 - Derivate des 5,6,7,9-Tetrahydro-1,2,3-trimethoxy-9-oxo-benzo(alpha)heptalens - Google Patents
Derivate des 5,6,7,9-Tetrahydro-1,2,3-trimethoxy-9-oxo-benzo(alpha)heptalensInfo
- Publication number
- DE69308009T2 DE69308009T2 DE69308009T DE69308009T DE69308009T2 DE 69308009 T2 DE69308009 T2 DE 69308009T2 DE 69308009 T DE69308009 T DE 69308009T DE 69308009 T DE69308009 T DE 69308009T DE 69308009 T2 DE69308009 T2 DE 69308009T2
- Authority
- DE
- Germany
- Prior art keywords
- heptalene
- trimethoxy
- benzo
- tetrahydro
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- YEKVYOOIQVZXSH-UHFFFAOYSA-N 2,3,4-trimethoxytricyclo[5.5.0.01,6]dodeca-2,4,6-trien-12-one Chemical class C1CCCC(=O)C2(C(OC)=C(C(OC)=C3)OC)C3=C21 YEKVYOOIQVZXSH-UHFFFAOYSA-N 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/34—Benzoheptalenes; Hydrogenated benzoheptalenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4358821A JPH06199749A (ja) | 1992-12-28 | 1992-12-28 | Ｎ−メチルデアセチルコルヒセインアミド誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69308009D1 DE69308009D1 (de) | 1997-03-20 |
| DE69308009T2 true DE69308009T2 (de) | 1997-08-28 |
Family
ID=18461286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69308009T Expired - Fee Related DE69308009T2 (de) | 1992-12-28 | 1993-04-23 | Derivate des 5,6,7,9-Tetrahydro-1,2,3-trimethoxy-9-oxo-benzo(alpha)heptalens |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5326786A (de) |
| EP (1) | EP0605078B1 (de) |
| JP (1) | JPH06199749A (de) |
| KR (1) | KR940014309A (de) |
| CN (1) | CN1088911A (de) |
| AT (1) | ATE148688T1 (de) |
| AU (1) | AU658502B2 (de) |
| CA (1) | CA2094753A1 (de) |
| DE (1) | DE69308009T2 (de) |
| DK (1) | DK0605078T3 (de) |
| ES (1) | ES2101951T3 (de) |
| GR (1) | GR3023322T3 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06211762A (ja) * | 1993-01-20 | 1994-08-02 | Bigen Kenkyusho:Kk | Ｎ−メチルデアセチルコルヒセインアミド誘導体 |
| US7056055B1 (en) | 2005-08-04 | 2006-06-06 | Wen-Nan Kuo | Traffic cone (2) |
| CN113024400A (zh) * | 2021-03-08 | 2021-06-25 | 沈阳药科大学 | 一种秋水仙碱衍生物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6179690A (en) * | 1989-08-09 | 1991-03-11 | Michael Reese Hospital And Medical Center | Method for detection and treatment of multiple drug-resistant tumor cells and useful colchicine derivative probes |
| AU634921B2 (en) * | 1990-12-25 | 1993-03-04 | Ohgen Research Laboratories Ltd. | Deacetylcolchicine derivatives |
| IT1244660B (it) * | 1991-03-06 | 1994-08-08 | Giorgio Bonura | Preparati farmaceutici per la terapia dei tumori contenenti colchicina come principio attivo e metodi per l'impiego degli stessi. |
-
1992
- 1992-12-28 JP JP4358821A patent/JPH06199749A/ja active Pending
-
1993
- 1993-04-23 CA CA002094753A patent/CA2094753A1/en not_active Abandoned
- 1993-04-23 US US08/051,297 patent/US5326786A/en not_active Expired - Fee Related
- 1993-04-23 AT AT93303190T patent/ATE148688T1/de not_active IP Right Cessation
- 1993-04-23 DE DE69308009T patent/DE69308009T2/de not_active Expired - Fee Related
- 1993-04-23 AU AU37094/93A patent/AU658502B2/en not_active Ceased
- 1993-04-23 ES ES93303190T patent/ES2101951T3/es not_active Expired - Lifetime
- 1993-04-23 EP EP93303190A patent/EP0605078B1/de not_active Expired - Lifetime
- 1993-04-23 DK DK93303190.8T patent/DK0605078T3/da active
- 1993-04-28 KR KR1019930007246A patent/KR940014309A/ko not_active Application Discontinuation
- 1993-05-04 CN CN93104964A patent/CN1088911A/zh active Pending
-
1997
- 1997-05-02 GR GR970400980T patent/GR3023322T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69308009D1 (de) | 1997-03-20 |
| EP0605078A1 (de) | 1994-07-06 |
| ES2101951T3 (es) | 1997-07-16 |
| CN1088911A (zh) | 1994-07-06 |
| CA2094753A1 (en) | 1994-06-29 |
| DK0605078T3 (da) | 1997-08-18 |
| ATE148688T1 (de) | 1997-02-15 |
| AU3709493A (en) | 1994-07-14 |
| KR940014309A (ko) | 1994-07-18 |
| GR3023322T3 (en) | 1997-08-29 |
| AU658502B2 (en) | 1995-04-13 |
| US5326786A (en) | 1994-07-05 |
| JPH06199749A (ja) | 1994-07-19 |
| EP0605078B1 (de) | 1997-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |