DE69300011T2 - Diacylglycerol-Nicotinate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. - Google Patents

Diacylglycerol-Nicotinate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.

Info

Publication number
DE69300011T2
DE69300011T2 DE69300011T DE69300011T DE69300011T2 DE 69300011 T2 DE69300011 T2 DE 69300011T2 DE 69300011 T DE69300011 T DE 69300011T DE 69300011 T DE69300011 T DE 69300011T DE 69300011 T2 DE69300011 T2 DE 69300011T2
Authority
DE
Germany
Prior art keywords
nicotinates
diacylglycerol
processes
preparation
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69300011T
Other languages
English (en)
Other versions
DE69300011D1 (de
Inventor
Alex Cordi
Jean-Michel Lacoste
Jacques Duhault
Joseph Espinal
Michelle Boulanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE69300011D1 publication Critical patent/DE69300011D1/de
Application granted granted Critical
Publication of DE69300011T2 publication Critical patent/DE69300011T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE69300011T 1992-06-10 1993-06-10 Diacylglycerol-Nicotinate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. Expired - Fee Related DE69300011T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR929206951A FR2692262B1 (fr) 1992-06-10 1992-06-10 Nouveaux nicotinates de diacylglycerols, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
DE69300011D1 DE69300011D1 (de) 1994-11-03
DE69300011T2 true DE69300011T2 (de) 1995-05-11

Family

ID=9430554

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69300011T Expired - Fee Related DE69300011T2 (de) 1992-06-10 1993-06-10 Diacylglycerol-Nicotinate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.

Country Status (12)

Country Link
US (1) US5385920A (de)
EP (1) EP0574312B1 (de)
JP (1) JPH07103106B2 (de)
AT (1) ATE112267T1 (de)
AU (1) AU657222B2 (de)
CA (1) CA2098069A1 (de)
DE (1) DE69300011T2 (de)
DK (1) DK0574312T3 (de)
ES (1) ES2065192T3 (de)
FR (1) FR2692262B1 (de)
NZ (1) NZ247820A (de)
ZA (1) ZA934110B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2220091C (en) * 1995-05-01 2011-01-04 Scotia Holdings Plc Nicotinic acid esters and pharmaceutical compositions containing them
USRE40546E1 (en) * 1996-05-01 2008-10-21 Scarista, Ltd. 1,3-Propane diol esters and ethers and methods for their use in drug delivery
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
WO2004101524A1 (en) * 2003-05-19 2004-11-25 Lonza Ag Polyglycerol esters of pyridinecarboxylic acids
CN112955115B (zh) * 2018-11-02 2023-06-30 联合利华知识产权控股有限公司 生物能烟酸甘油酯、组合物和使用其的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8101585A1 (es) * 1980-02-15 1980-12-16 Especialidades Farmaco Terape Procedimiento de obtencion de un nuevo compuesto antiateros-clerotico

Also Published As

Publication number Publication date
AU657222B2 (en) 1995-03-02
DE69300011D1 (de) 1994-11-03
AU4012393A (en) 1993-12-16
CA2098069A1 (fr) 1993-12-10
EP0574312B1 (de) 1994-09-28
FR2692262A1 (fr) 1993-12-17
NZ247820A (en) 1994-10-26
ZA934110B (en) 1994-01-07
ATE112267T1 (de) 1994-10-15
FR2692262B1 (fr) 1994-08-05
EP0574312A1 (de) 1993-12-15
JPH07103106B2 (ja) 1995-11-08
ES2065192T3 (es) 1995-02-01
JPH0656786A (ja) 1994-03-01
US5385920A (en) 1995-01-31
DK0574312T3 (da) 1995-04-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee