DE69232779D1 - Menschlicher Rezeptor für das Follikel-stimulierendes Hormon. - Google Patents

Menschlicher Rezeptor für das Follikel-stimulierendes Hormon.

Info

Publication number
DE69232779D1
DE69232779D1 DE69232779T DE69232779T DE69232779D1 DE 69232779 D1 DE69232779 D1 DE 69232779D1 DE 69232779 T DE69232779 T DE 69232779T DE 69232779 T DE69232779 T DE 69232779T DE 69232779 D1 DE69232779 D1 DE 69232779D1
Authority
DE
Germany
Prior art keywords
receptor
mutant
fragment
fsh
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232779T
Other languages
English (en)
Other versions
DE69232779T2 (de
Inventor
Christie Ann Kelton
Shirley Vui Yen Cheng
Noreen Patrice Nugent
Rene Lynn Schweickhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Serono SA
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24688922&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69232779(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Publication of DE69232779D1 publication Critical patent/DE69232779D1/de
Application granted granted Critical
Publication of DE69232779T2 publication Critical patent/DE69232779T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
DE69232779T 1991-03-15 1992-01-02 Menschlicher Rezeptor für das Follikel-stimulierendes Hormon. Expired - Lifetime DE69232779T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67008591A 1991-03-15 1991-03-15
PCT/US1992/000122 WO1992016620A1 (en) 1991-03-15 1992-01-02 Human follicle stimulating hormone receptor

Publications (2)

Publication Number Publication Date
DE69232779D1 true DE69232779D1 (de) 2002-10-24
DE69232779T2 DE69232779T2 (de) 2003-01-30

Family

ID=24688922

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69233805T Expired - Lifetime DE69233805D1 (de) 1991-03-15 1992-01-02 Rezeptor für das menschliche Follikel-stimulierende Hormon
DE69232779T Expired - Lifetime DE69232779T2 (de) 1991-03-15 1992-01-02 Menschlicher Rezeptor für das Follikel-stimulierendes Hormon.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69233805T Expired - Lifetime DE69233805D1 (de) 1991-03-15 1992-01-02 Rezeptor für das menschliche Follikel-stimulierende Hormon

Country Status (19)

Country Link
US (3) US5744448A (de)
EP (2) EP1167385B1 (de)
JP (1) JP3581148B2 (de)
KR (1) KR100245250B1 (de)
AT (2) ATE224446T1 (de)
AU (1) AU671417B2 (de)
CA (1) CA2106061C (de)
DE (2) DE69233805D1 (de)
DK (1) DK0575357T3 (de)
ES (1) ES2183806T3 (de)
FI (1) FI109360B (de)
GE (1) GEP19991604B (de)
LT (1) LT3973B (de)
LV (1) LV10724B (de)
MX (1) MX9203350A (de)
NO (1) NO315517B1 (de)
RU (1) RU2193599C2 (de)
UA (1) UA43826C2 (de)
WO (1) WO1992016620A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993020199A1 (en) * 1992-03-30 1993-10-14 Akzo Nobel N.V. Human gonadotropin receptor (fsh receptor)
SI0894141T1 (en) 1996-02-20 2005-10-31 Applied Research Systems Ars Holding N.V. Hybrid proteins which form heterodimers
CA2250975A1 (en) * 1996-04-15 1997-10-23 The Board Of Trustees Of The Leland Stanford Junior University Soluble 7-transmembrane domain g-protein-coupled receptor compositions and methods
US6521641B1 (en) 1998-10-08 2003-02-18 Allergan, Inc. Male anti-fertility agents
WO2000073416A1 (en) * 1999-05-28 2000-12-07 University Of Cincinnati Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use
EP1287135A2 (de) * 2000-05-18 2003-03-05 Bayer Aktiengesellschaft Regulation eines menschlichen, follikel-stimulierenden hormon-ähnlichen g-protein gekoppelten rezeptors
US20030175889A1 (en) * 2002-01-23 2003-09-18 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated versions of human G protein coupled receptor: FSHR
EP1466620A1 (de) * 2003-04-11 2004-10-13 AXXAM S.r.l. Modulatoren des Follikel-stimulierenden Hormon-Rezeptors und ihre therapeutische Verwendung
US20100061976A1 (en) * 2008-07-24 2010-03-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652450A (en) * 1984-08-31 1987-03-24 Research Corporation Bacterial FSH binding inhibitor
US4761371A (en) 1985-02-12 1988-08-02 Genentech, Inc. Insulin receptor
US4859609A (en) * 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US4921808A (en) * 1986-06-25 1990-05-01 The Albany Medical College Of Union University Method for determining follicle stimulating hormone
US4960700A (en) * 1986-12-24 1990-10-02 Genentech, Inc. Compositions and methods for the synthesis and assay of a mammalian enkephalinase
JPH04505103A (ja) * 1989-05-05 1992-09-10 ジェネンテク，インコーポレイテッド 糖タンパク質ホルモン受容体分子
US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors

Also Published As

Publication number Publication date
AU1251492A (en) 1992-10-21
FI109360B (fi) 2002-07-15
ATE224446T1 (de) 2002-10-15
FI934023A (fi) 1993-09-14
UA43826C2 (uk) 2002-01-15
MX9203350A (es) 1992-08-01
ES2183806T3 (es) 2003-04-01
US5744448A (en) 1998-04-28
JPH06505157A (ja) 1994-06-16
DE69233805D1 (de) 2011-05-26
DE69232779T2 (de) 2003-01-30
LT3973B (en) 1996-05-27
WO1992016620A1 (en) 1992-10-01
CA2106061A1 (en) 1992-09-16
AU671417B2 (en) 1996-08-29
LTIP1631A (en) 1995-07-25
EP0575357A1 (de) 1993-12-29
LV10724B (en) 1995-12-20
JP3581148B2 (ja) 2004-10-27
NO315517B1 (no) 2003-09-15
EP1167385A3 (de) 2003-04-16
RU2193599C2 (ru) 2002-11-27
KR100245250B1 (en) 2000-02-15
FI934023A0 (fi) 1993-09-14
NO933272L (no) 1993-09-14
ATE505486T1 (de) 2011-04-15
LV10724A (lv) 1995-06-20
US6372711B1 (en) 2002-04-16
EP1167385B1 (de) 2011-04-13
NO933272D0 (no) 1993-09-14
GEP19991604B (en) 1999-04-29
CA2106061C (en) 2008-10-07
DK0575357T3 (da) 2002-11-25
EP0575357B1 (de) 2002-09-18
US6121016A (en) 2000-09-19
EP1167385A2 (de) 2002-01-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: LABORATOIRES SERONO S.A., COINSINS, VAUD, CH

8328 Change in the person/name/address of the agent

Representative=s name: WESTENDORP SOMMER, 80336 MUENCHEN