ES2183806T3 - Receptor de la hormona estimuladora de foliculo humano. - Google Patents

Receptor de la hormona estimuladora de foliculo humano.

Info

Publication number
ES2183806T3
ES2183806T3 ES92904833T ES92904833T ES2183806T3 ES 2183806 T3 ES2183806 T3 ES 2183806T3 ES 92904833 T ES92904833 T ES 92904833T ES 92904833 T ES92904833 T ES 92904833T ES 2183806 T3 ES2183806 T3 ES 2183806T3
Authority
ES
Spain
Prior art keywords
mutant
fragment
receptor
human
fsh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92904833T
Other languages
English (en)
Inventor
Christie Ann Kelton
Shirley Vui Yen Cheng
Noreen Patrice Nugent
Rene Lynn Schweickhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24688922&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2183806(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Application granted granted Critical
Publication of ES2183806T3 publication Critical patent/ES2183806T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)

Abstract

LA INVENCION SE REFIERE ESENCIALMENTE A UN RECEPTOR FSH HUMANO PURO, O A UN FRAGMENTO O UN MUTANTE DEL MISMO QUE SE UNA AL FSH, AL DNA QUE CODIFICA DICHO RECEPTOR, A LOS FRAGMENTOS O MUTANTES, A LOS VECTORES DE EXPRESION QUE COMPRENDEN DICHO DNA, A CELULAS TRANSFECTADAS CON DICHOS VECTORES DE EXPRESION, Y A METODOS PARA PRODUCIR DICHO RECEPTOR, FRAGMENTO O MUTANTE CULTIVANDO DICHAS CELULAS TRANSFECTADAS. LA INVENCION TAMBIEN INCLUYE COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN DICHO RECEPTOR, FRAGMENTO O MUTANTE, ASI COMO A METODOS PARA TRATAR PACIENTES CON TALES COMPOSICIONES PARA REDUCIR LA BIOACTIVIDAD DEL FSH ENDOGENO. TAMBIEN SE PRESENTA UN ENSAYO MEJORADO PARA EL FSH HUMANO QUE USA EL RECEPTOR, FRAGMENTO O MUTANTE DE LA INVENCION.
ES92904833T 1991-03-15 1992-01-02 Receptor de la hormona estimuladora de foliculo humano. Expired - Lifetime ES2183806T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67008591A 1991-03-15 1991-03-15

Publications (1)

Publication Number Publication Date
ES2183806T3 true ES2183806T3 (es) 2003-04-01

Family

ID=24688922

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92904833T Expired - Lifetime ES2183806T3 (es) 1991-03-15 1992-01-02 Receptor de la hormona estimuladora de foliculo humano.

Country Status (19)

Country Link
US (3) US6121016A (es)
EP (2) EP1167385B1 (es)
JP (1) JP3581148B2 (es)
KR (1) KR100245250B1 (es)
AT (2) ATE224446T1 (es)
AU (1) AU671417B2 (es)
CA (1) CA2106061C (es)
DE (2) DE69233805D1 (es)
DK (1) DK0575357T3 (es)
ES (1) ES2183806T3 (es)
FI (1) FI109360B (es)
GE (1) GEP19991604B (es)
LT (1) LT3973B (es)
LV (1) LV10724B (es)
MX (1) MX9203350A (es)
NO (1) NO315517B1 (es)
RU (1) RU2193599C2 (es)
UA (1) UA43826C2 (es)
WO (1) WO1992016620A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3949893A (en) * 1992-03-30 1993-11-08 Akzo Nobel N.V. Human gonadotropin receptor (FSH receptor)
EP1541689B1 (en) 1996-02-20 2012-09-05 Merck Serono SA Hybrid proteins which form heterodimers
WO1997039131A1 (en) * 1996-04-15 1997-10-23 The Board Of Trustees Of The Leland Stanford Junior University Soluble 7-transmembrane domain g-protein-coupled receptor compositions and methods
US6521641B1 (en) 1998-10-08 2003-02-18 Allergan, Inc. Male anti-fertility agents
US7273932B1 (en) 1999-05-28 2007-09-25 The University Of Cincinnati Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use
US20040077041A1 (en) * 2000-05-18 2004-04-22 Shyam Ramakrishnan Regulation of human follicle stimulating hormone-like g protein -coupled receptor
WO2003062396A2 (en) * 2002-01-23 2003-07-31 Arena Pharmaceuticals, Inc. Non-endogenous versions of human g protein-coupled receptor: fshr
EP1466620A1 (en) * 2003-04-11 2004-10-13 AXXAM S.r.l. Compounds modulating FSHR and therapeutic uses thereof
US20100061976A1 (en) * 2008-07-24 2010-03-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652450A (en) * 1984-08-31 1987-03-24 Research Corporation Bacterial FSH binding inhibitor
US4761371A (en) 1985-02-12 1988-08-02 Genentech, Inc. Insulin receptor
US4859609A (en) * 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US4921808A (en) * 1986-06-25 1990-05-01 The Albany Medical College Of Union University Method for determining follicle stimulating hormone
US4960700A (en) * 1986-12-24 1990-10-02 Genentech, Inc. Compositions and methods for the synthesis and assay of a mammalian enkephalinase
US5057417A (en) 1987-06-12 1991-10-15 Genentech, Inc. Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
ES2068388T3 (es) * 1989-05-05 1995-04-16 Genentech Inc Moleculas de receptor de hormona de la glucoproteina.
US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors

Also Published As

Publication number Publication date
CA2106061C (en) 2008-10-07
NO315517B1 (no) 2003-09-15
LV10724A (lv) 1995-06-20
AU671417B2 (en) 1996-08-29
EP1167385A3 (en) 2003-04-16
LV10724B (en) 1995-12-20
DK0575357T3 (da) 2002-11-25
FI109360B (fi) 2002-07-15
GEP19991604B (en) 1999-04-29
EP1167385A2 (en) 2002-01-02
CA2106061A1 (en) 1992-09-16
FI934023A (fi) 1993-09-14
LTIP1631A (en) 1995-07-25
AU1251492A (en) 1992-10-21
US6121016A (en) 2000-09-19
JP3581148B2 (ja) 2004-10-27
DE69232779D1 (de) 2002-10-24
DE69232779T2 (de) 2003-01-30
EP0575357B1 (en) 2002-09-18
NO933272L (no) 1993-09-14
DE69233805D1 (de) 2011-05-26
EP1167385B1 (en) 2011-04-13
ATE505486T1 (de) 2011-04-15
UA43826C2 (uk) 2002-01-15
US6372711B1 (en) 2002-04-16
KR100245250B1 (en) 2000-02-15
JPH06505157A (ja) 1994-06-16
LT3973B (en) 1996-05-27
EP0575357A1 (en) 1993-12-29
MX9203350A (es) 1992-08-01
FI934023A0 (fi) 1993-09-14
ATE224446T1 (de) 2002-10-15
WO1992016620A1 (en) 1992-10-01
NO933272D0 (no) 1993-09-14
US5744448A (en) 1998-04-28
RU2193599C2 (ru) 2002-11-27

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