DE69231629D1 - Verfahren zur Herstellung von fluorisierten Benzoesäuren - Google Patents

Verfahren zur Herstellung von fluorisierten Benzoesäuren

Info

Publication number
DE69231629D1
DE69231629D1 DE69231629T DE69231629T DE69231629D1 DE 69231629 D1 DE69231629 D1 DE 69231629D1 DE 69231629 T DE69231629 T DE 69231629T DE 69231629 T DE69231629 T DE 69231629T DE 69231629 D1 DE69231629 D1 DE 69231629D1
Authority
DE
Germany
Prior art keywords
preparation
chloro
acid
benzoic acids
fluorinated benzoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69231629T
Other languages
English (en)
Other versions
DE69231629T2 (de
Inventor
Xiu C Wang
P Kalaritis
Michelle L Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69231629D1 publication Critical patent/DE69231629D1/de
Application granted granted Critical
Publication of DE69231629T2 publication Critical patent/DE69231629T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69231629T 1991-10-31 1992-10-30 Verfahren zur Herstellung von fluorisierten Benzoesäuren Expired - Lifetime DE69231629T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78585191A 1991-10-31 1991-10-31

Publications (2)

Publication Number Publication Date
DE69231629D1 true DE69231629D1 (de) 2001-02-08
DE69231629T2 DE69231629T2 (de) 2001-08-02

Family

ID=25136820

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69222055T Expired - Lifetime DE69222055T2 (de) 1991-10-31 1992-10-30 Verfahren zur herstellung von fluorinierten benzoesäuren
DE69231629T Expired - Lifetime DE69231629T2 (de) 1991-10-31 1992-10-30 Verfahren zur Herstellung von fluorisierten Benzoesäuren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69222055T Expired - Lifetime DE69222055T2 (de) 1991-10-31 1992-10-30 Verfahren zur herstellung von fluorinierten benzoesäuren

Country Status (9)

Country Link
EP (2) EP0610384B1 (de)
JP (3) JP3350051B2 (de)
AT (2) ATE157642T1 (de)
AU (1) AU2911992A (de)
DE (2) DE69222055T2 (de)
DK (2) DK0781757T3 (de)
ES (2) ES2106889T3 (de)
GR (2) GR3025419T3 (de)
WO (1) WO1993009077A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294721A (en) * 1992-08-21 1994-03-15 Abbott Laboratories Process for the preparation of pyridinium intermediates
US6469181B1 (en) * 1995-01-30 2002-10-22 Catalytica, Inc. Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles
CN1082505C (zh) * 1996-02-01 2002-04-10 罗纳-普朗克农业化学公司 制备二酮化合物的方法
AU2001272757A1 (en) 2000-07-19 2002-01-30 Ube Industries Ltd. Process for producing 5-fluorooxyindole and for producing intermediate therefor
ITMI20050275A1 (it) * 2005-02-22 2006-08-23 Miteni Spa Procedimento per la preparazione di derivati dell'acido benzoico attraverso un nuovo intermedio di sintesi
JP2007063294A (ja) * 2006-12-11 2007-03-15 Ube Ind Ltd ２−（５−クロロ−２−ニトロフェニル）−２−置換酢酸エステル誘導体の製法
JP5524071B2 (ja) 2007-10-24 2014-06-18 メルク・シャープ・アンド・ドーム・コーポレーション 複素環フェニルアミドｔ型カルシウムチャネルアンタゴニスト

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1443825A1 (de) * 1962-02-24 1969-12-18 Hoechst Ag Verfahren zur Herstellung von gegebenenfalls halogensubstituierten Mononitrobenzotrichloriden
US4730000A (en) 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
JPS60130537A (ja) * 1983-12-16 1985-07-12 Asahi Glass Co Ltd 芳香族フツ素化合物の製法
US4788320A (en) * 1986-01-20 1988-11-29 Kyorin Pharmaceutical Co., Ltd. Benzoylacetic acid ester derivatives and process for their preparations
JP2577567B2 (ja) * 1987-07-07 1997-02-05 イハラケミカル工業株式会社 芳香族フッ素化合物の製造方法
ES2074047T3 (es) * 1987-08-14 1995-09-01 Asahi Glass Co Ltd Compuestos de benzoilo fluorados.
KR910003630B1 (ko) * 1988-06-17 1991-06-07 한국과학기술원 벤조일 아세틱 에스테르 유도체 및 그 제조방법
DE3827436A1 (de) * 1988-08-12 1990-02-15 Bayer Ag Verfahren zum einfuehren von fluoratomen an aromatische kerne durch nucleophilen austausch
US5294721A (en) * 1992-08-21 1994-03-15 Abbott Laboratories Process for the preparation of pyridinium intermediates

Also Published As

Publication number Publication date
JP3350051B2 (ja) 2002-11-25
ES2154853T3 (es) 2001-04-16
DE69222055T2 (de) 1998-03-19
AU2911992A (en) 1993-06-07
JP2006070043A (ja) 2006-03-16
DK0781757T3 (da) 2001-02-12
WO1993009077A3 (en) 1993-06-10
JP3746462B2 (ja) 2006-02-15
JPH07500837A (ja) 1995-01-26
EP0610384A4 (de) 1995-01-25
GR3025419T3 (en) 1998-02-27
ATE157642T1 (de) 1997-09-15
EP0781757B1 (de) 2001-01-03
ES2106889T3 (es) 1997-11-16
DE69231629T2 (de) 2001-08-02
JP4002283B2 (ja) 2007-10-31
EP0610384A1 (de) 1994-08-17
EP0610384B1 (de) 1997-09-03
JP2002308834A (ja) 2002-10-23
DK0610384T3 (da) 1998-04-20
WO1993009077A2 (en) 1993-05-13
GR3035514T3 (en) 2001-06-29
DE69222055D1 (de) 1997-10-09
EP0781757A1 (de) 1997-07-02
ATE198468T1 (de) 2001-01-15

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