DE69230787T2 - Polymere Phosphoniumsalze, die Chemilumineszenzverstärkung von 1,2-Dioxetanen hervorrufen, und deren Verwendung. - Google Patents
Polymere Phosphoniumsalze, die Chemilumineszenzverstärkung von 1,2-Dioxetanen hervorrufen, und deren Verwendung.Info
- Publication number
- DE69230787T2 DE69230787T2 DE69230787T DE69230787T DE69230787T2 DE 69230787 T2 DE69230787 T2 DE 69230787T2 DE 69230787 T DE69230787 T DE 69230787T DE 69230787 T DE69230787 T DE 69230787T DE 69230787 T2 DE69230787 T2 DE 69230787T2
- Authority
- DE
- Germany
- Prior art keywords
- dioxetanes
- phosphonium salts
- polymeric phosphonium
- chemiluminescence enhancement
- induce chemiluminescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/855,537 US5393469A (en) | 1992-03-20 | 1992-03-20 | Polymeric phosphonium salts providing enhanced chemiluminescence from 1,2-dioxetanes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69230787D1 DE69230787D1 (de) | 2000-04-20 |
DE69230787T2 true DE69230787T2 (de) | 2000-11-23 |
Family
ID=25321510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69230787T Expired - Lifetime DE69230787T2 (de) | 1992-03-20 | 1992-08-06 | Polymere Phosphoniumsalze, die Chemilumineszenzverstärkung von 1,2-Dioxetanen hervorrufen, und deren Verwendung. |
Country Status (5)
Country | Link |
---|---|
US (5) | US5393469A (de) |
EP (1) | EP0561033B1 (de) |
JP (2) | JP2648423B2 (de) |
AT (1) | ATE190724T1 (de) |
DE (1) | DE69230787T2 (de) |
Families Citing this family (41)
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US5336596A (en) * | 1991-12-23 | 1994-08-09 | Tropix, Inc. | Membrane for chemiluminescent blotting applications |
US5395752A (en) * | 1993-03-19 | 1995-03-07 | Ciba Corning Diagnostics Corp. | Long emission wavelength chemiluminescent compounds and their use in test assays |
US5451347A (en) * | 1993-06-24 | 1995-09-19 | Lumigen, Inc. | Methods and compositions providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants |
FR2710655B1 (fr) * | 1993-09-29 | 1995-12-01 | Inst Nat Rech Securite | Procédé pour effectuer un test biologique destiné à identifier et à doser des gènes, des protéines et autres molécules. |
US5773628A (en) * | 1994-11-14 | 1998-06-30 | Tropix, Inc. | 1,2-dioxetane compounds with haloalkoxy groups, methods preparation and use |
US5846753A (en) * | 1995-05-30 | 1998-12-08 | The United States Of America As Represented By The Secretary Of The Army | Chemiluminescence-based method for rapid and sensitive in-situ detection of organophosphorus compounds and metal ions |
US5631167A (en) * | 1995-07-31 | 1997-05-20 | Bayer Corporation | Capsule chemistry analytical methods employing dioxetane chemiluminescence |
US5777135A (en) * | 1995-07-31 | 1998-07-07 | Lumigen, Inc. | Di-substituted 1,2-dioxetane compounds having increased water solubility and assay compositions |
US5721370A (en) * | 1995-07-31 | 1998-02-24 | Lumigen Inc. | Water soluble tri-substituted 1,2-dioxetane compounds and assay compositions having increased storage stability |
US5783381A (en) * | 1995-10-19 | 1998-07-21 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
KR20000070711A (ko) | 1997-02-03 | 2000-11-25 | 에프. 아. 프라저, 에른스트 알테르 (에. 알테르), 한스 페터 비틀린 (하. 페. 비틀린), 피. 랍 보프, 브이. 스펜글러, 페. 아에글러 | 형광 조성물 및 이의 용도 |
US5772926A (en) * | 1997-05-13 | 1998-06-30 | Lumigen, Inc. | Chemiluminescent reactions using dihydroxyaromatic compounds and heterocyclic enol phosphates |
US6555698B1 (en) * | 1998-11-17 | 2003-04-29 | Tropix, Inc. | Chemiluminescent substrates for neuraminidase, assays for detection of neuraminidase and kits therefor |
US6783948B1 (en) * | 1999-07-30 | 2004-08-31 | Bayer Corporation | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes |
JP2001249079A (ja) * | 1999-12-28 | 2001-09-14 | Fujirebio Inc | 発光量調節剤を用いた化学発光測定方法及び酵素免疫測定方法 |
US6852503B1 (en) * | 2001-05-30 | 2005-02-08 | Pierce Biotechnology, Inc. | Compositions and methods for utilizing mixed substrate solutions of luminols and dioxetanes |
US6774249B2 (en) | 2001-09-27 | 2004-08-10 | Lumigen, Inc. | Uses of improved polymer-supported photosensitizers in the generation of singlet oxygen |
US6545102B1 (en) | 2001-09-27 | 2003-04-08 | Lumigen, Inc. | Polymer-supported photosensitizers |
US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
EP1534697A4 (de) * | 2002-05-23 | 2009-12-16 | Brij P Giri | Polymere ammonium- und/oder phosphoniumsalze mit zusätzlichen -elektronen und höherem molekulargewicht als verstärker für chemilumineszente systeme |
AU2003244177A1 (en) | 2002-06-24 | 2004-01-06 | Fujirebio Inc. | Chemiluminescence enhancer |
US7390670B2 (en) | 2003-02-20 | 2008-06-24 | Lumigen, Inc. | Signalling compounds and methods for detecting hydrogen peroxide |
JP4259229B2 (ja) | 2003-08-28 | 2009-04-30 | 東ソー株式会社 | 1,2−ジオキセタンの化学発光方法および化学発光用組成物 |
US20060033088A1 (en) * | 2004-07-27 | 2006-02-16 | Gyongtae Kim | Polymer for a photochromic compound matrix, and a matrix comprising the said polymer |
US7645719B2 (en) * | 2004-10-13 | 2010-01-12 | Ncr Corporation | Thermal paper with security features |
US7504044B2 (en) * | 2004-11-05 | 2009-03-17 | Cabot Microelectronics Corporation | Polishing composition and method for high silicon nitride to silicon oxide removal rate ratios |
US7531105B2 (en) * | 2004-11-05 | 2009-05-12 | Cabot Microelectronics Corporation | Polishing composition and method for high silicon nitride to silicon oxide removal rate ratios |
US20060234251A1 (en) * | 2005-04-19 | 2006-10-19 | Lumigen, Inc. | Methods of enhancing isolation of RNA from biological samples |
US20090246888A1 (en) * | 2005-04-27 | 2009-10-01 | The Trustees Of The University Of Pennsylvania | Nanoassays |
WO2007142314A1 (ja) * | 2006-06-08 | 2007-12-13 | Fujirebio Inc. | 発光増幅剤 |
US9129907B2 (en) * | 2006-09-08 | 2015-09-08 | Cabot Microelectronics Corporation | Onium-containing CMP compositions and methods of use thereof |
CN102311731B (zh) | 2010-06-30 | 2016-08-03 | 深圳迈瑞生物医疗电子股份有限公司 | 增强化学发光的试剂、方法和化学发光液 |
CN102311730B (zh) | 2010-06-30 | 2014-09-24 | 深圳迈瑞生物医疗电子股份有限公司 | 化学发光液,增强化学发光的试剂和方法 |
CN102329611B (zh) | 2010-07-13 | 2015-01-07 | 深圳迈瑞生物医疗电子股份有限公司 | 化学发光增强试剂及其使用方法和化学发光液 |
EP2906382B2 (de) * | 2012-09-07 | 2023-11-01 | Bekaert Binjiang Steel Cord Co., Ltd. | Geformter sägedraht mit restspannungen unter der oberfläche |
CN104597233B (zh) * | 2014-11-05 | 2016-09-14 | 深圳市美凯特科技有限公司 | 用于增强化学发光的增强液及制备化学发光液的方法 |
WO2017165861A1 (en) * | 2016-03-25 | 2017-09-28 | Floyd William Clary | Light-activated coating and materials |
AU2017290887B2 (en) | 2016-06-30 | 2021-08-05 | Beckman Coulter, Inc. | Chemiluminescent substrates |
US11274230B1 (en) * | 2021-04-27 | 2022-03-15 | Rohm And Haas Electronic Materials Cmp Holdings, Inc. | Polishing composition and method of polishing a substrate having enhanced defect inhibition |
EP4352120A1 (de) * | 2021-06-10 | 2024-04-17 | Versum Materials US, LLC | Polymere und copolymere auf phosphoniumbasis als additive für aufschlämmungen zur chemisch-mechanischen planarisierung |
WO2024026467A1 (en) | 2022-07-29 | 2024-02-01 | Beckman Coulter, Inc. | Chemiluminescent reagents for detection of alkaline phosphatases |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS502559Y1 (de) * | 1969-11-26 | 1975-01-23 | ||
US4069017A (en) * | 1977-01-14 | 1978-01-17 | Eastman Kodak Company | Colorimetric assay for bilirubin |
US4204839A (en) * | 1978-08-09 | 1980-05-27 | Eastman Kodak Company | Fluorimetric analysis method for bilirubin |
US4412005A (en) * | 1979-10-25 | 1983-10-25 | Eastman Kodak Company | Determination of total bilirubin |
US4338095A (en) * | 1980-07-11 | 1982-07-06 | Eastman Kodak Company | Method for selective determination of conjugated and unconjugated bilirubin |
US4446284A (en) * | 1982-05-28 | 1984-05-01 | The Goodyear Tire & Rubber Company | Method for preparing a polymer containing pendant unsaturation |
GB8420053D0 (en) * | 1984-08-07 | 1984-09-12 | Secr Social Service Brit | Enhanced luminescent/luminometric assay |
US4959182A (en) * | 1986-07-17 | 1990-09-25 | Board Of Governors Of Wayne State University | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes |
US4857652A (en) * | 1986-07-17 | 1989-08-15 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
US5013827A (en) * | 1986-07-17 | 1991-05-07 | Board Of Governors Of Wayne State University | Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers |
US5004565A (en) * | 1986-07-17 | 1991-04-02 | The Board Of Governors Of Wayne State University | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes |
US4978614A (en) * | 1988-10-26 | 1990-12-18 | Tropix, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
US4931223A (en) * | 1986-07-24 | 1990-06-05 | Tropix, Inc. | Methods of using chemiluminescent 1,2-dioxetanes |
BR8707399A (pt) * | 1986-07-24 | 1988-09-13 | Quest Systems Inc | Metodo de detectar uma substancia usando decomposicao enzimaticamente induzida de dioxetanos |
JPS63186229A (ja) * | 1987-01-28 | 1988-08-01 | Fuji Photo Film Co Ltd | 感光材料 |
JPH07120080B2 (ja) * | 1987-03-31 | 1995-12-20 | 藤倉化成株式会社 | 静電潜像現像トナ−用正電荷制御剤およびそれを含有するトナ− |
US4927769A (en) * | 1987-07-08 | 1990-05-22 | Ciba Corning Diagnostics Corp. | Method for enhancement of chemiluminescence |
JPH01170943A (ja) * | 1987-12-25 | 1989-07-06 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料の処理方法 |
DE68919761T2 (de) * | 1988-01-06 | 1995-05-11 | Fuji Photo Film Co Ltd | Verfahren zur verarbeitung photographischen silberhalogenid- materials. |
US4952707A (en) * | 1988-06-30 | 1990-08-28 | Tropix, Inc. | Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes |
US5032381A (en) * | 1988-12-20 | 1991-07-16 | Tropix, Inc. | Chemiluminescence-based static and flow cytometry |
GB2233451B (en) * | 1989-06-27 | 1993-09-15 | Tropix Inc | Chemiluminescence enhancement |
JPH04266880A (ja) * | 1991-02-22 | 1992-09-22 | Japan Tobacco Inc | 3 −dpa− ラクトンの製造方法 |
-
1992
- 1992-03-20 US US07/855,537 patent/US5393469A/en not_active Expired - Lifetime
- 1992-08-06 DE DE69230787T patent/DE69230787T2/de not_active Expired - Lifetime
- 1992-08-06 EP EP92113448A patent/EP0561033B1/de not_active Expired - Lifetime
- 1992-08-06 AT AT92113448T patent/ATE190724T1/de not_active IP Right Cessation
- 1992-10-08 JP JP4270457A patent/JP2648423B2/ja not_active Expired - Lifetime
-
1994
- 1994-02-10 US US08/194,517 patent/US5431845A/en not_active Expired - Lifetime
- 1994-02-14 US US08/195,100 patent/US5439617A/en not_active Expired - Lifetime
- 1994-02-14 US US08/195,439 patent/US5474725A/en not_active Expired - Lifetime
-
1995
- 1995-08-14 US US08/514,833 patent/US5582775A/en not_active Expired - Lifetime
-
1996
- 1996-07-31 JP JP20154196A patent/JP3471530B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5393469A (en) | 1995-02-28 |
JP3471530B2 (ja) | 2003-12-02 |
US5439617A (en) | 1995-08-08 |
US5582775A (en) | 1996-12-10 |
EP0561033B1 (de) | 2000-03-15 |
JPH09136923A (ja) | 1997-05-27 |
EP0561033A1 (de) | 1993-09-22 |
JP2648423B2 (ja) | 1997-08-27 |
US5474725A (en) | 1995-12-12 |
ATE190724T1 (de) | 2000-04-15 |
US5431845A (en) | 1995-07-11 |
DE69230787D1 (de) | 2000-04-20 |
JPH05287267A (ja) | 1993-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R071 | Expiry of right |
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