DE69227776T2 - Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden - Google Patents

Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden

Info

Publication number
DE69227776T2
DE69227776T2 DE69227776T DE69227776T DE69227776T2 DE 69227776 T2 DE69227776 T2 DE 69227776T2 DE 69227776 T DE69227776 T DE 69227776T DE 69227776 T DE69227776 T DE 69227776T DE 69227776 T2 DE69227776 T2 DE 69227776T2
Authority
DE
Germany
Prior art keywords
hcv
antibody
antigen
test sample
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69227776T
Other languages
German (de)
English (en)
Other versions
DE69227776D1 (de
Inventor
Stephen H. Vernon Hills Il 60061 Dailey
Suresh M. Libertyville Il 60048 Desai
Sushil G. Northbrook Il 60062 Devare
Jill E. Waukegan Il 60085 Johnson
Smriti U. Libertyville Il 60048 Mehta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69227776D1 publication Critical patent/DE69227776D1/de
Application granted granted Critical
Publication of DE69227776T2 publication Critical patent/DE69227776T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109Hepatitis C virus; Hepatitis G virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69227776T 1991-08-21 1992-08-21 Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden Expired - Lifetime DE69227776T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74856391A 1991-08-21 1991-08-21
PCT/US1992/006965 WO1993004084A1 (en) 1991-08-21 1992-08-21 Monoclonal antibodies to putative hcv ns5 proteins and methos for using same

Publications (2)

Publication Number Publication Date
DE69227776D1 DE69227776D1 (de) 1999-01-14
DE69227776T2 true DE69227776T2 (de) 1999-07-01

Family

ID=25009975

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69227776T Expired - Lifetime DE69227776T2 (de) 1991-08-21 1992-08-21 Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden

Country Status (10)

Country Link
EP (1) EP0599913B1 (el)
JP (1) JPH06510188A (el)
AT (1) ATE174060T1 (el)
AU (1) AU2501392A (el)
CA (1) CA2112667C (el)
DE (1) DE69227776T2 (el)
DK (1) DK0599913T3 (el)
ES (1) ES2126598T3 (el)
GR (1) GR3029320T3 (el)
WO (1) WO1993004084A1 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非a非b型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
CN1044384C (zh) * 1994-08-25 1999-07-28 中国药品生物制品检定所 抗丙型肝炎病毒抗原单克隆抗体细胞株建立及其单克隆抗体
ES2456961T3 (es) 2007-02-21 2014-04-24 University Of Massachusetts Anticuerpos humanos contra el virus de la hepatitis C (VHC), usos de los mismos
CN110320364B (zh) * 2018-03-30 2023-03-31 洛阳普泰生物技术有限公司 一种双抗夹心胶体金检测试剂盒、及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) * 1987-11-18 2000-02-23 希龙股份有限公司 非a和非b肝炎病毒的诊断及疫苗
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
US5120662A (en) * 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
CA2032907C (en) * 1989-12-22 2002-05-14 Richard R. Lesniewski Hepatitis c assay
EP0933426A1 (en) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens

Also Published As

Publication number Publication date
EP0599913A4 (en) 1995-01-18
DK0599913T3 (da) 1999-08-16
ATE174060T1 (de) 1998-12-15
ES2126598T3 (es) 1999-04-01
DE69227776D1 (de) 1999-01-14
CA2112667A1 (en) 1993-03-04
CA2112667C (en) 2004-02-17
JPH06510188A (ja) 1994-11-17
WO1993004084A1 (en) 1993-03-04
EP0599913B1 (en) 1998-12-02
GR3029320T3 (en) 1999-05-28
EP0599913A1 (en) 1994-06-08
AU2501392A (en) 1993-03-16

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