DE69227347D1 - Auf rezeptorgrundlage arbeitende screening-verfahren für amylin-agonisten und- antagonisten - Google Patents
Auf rezeptorgrundlage arbeitende screening-verfahren für amylin-agonisten und- antagonistenInfo
- Publication number
- DE69227347D1 DE69227347D1 DE69227347T DE69227347T DE69227347D1 DE 69227347 D1 DE69227347 D1 DE 69227347D1 DE 69227347 T DE69227347 T DE 69227347T DE 69227347 T DE69227347 T DE 69227347T DE 69227347 D1 DE69227347 D1 DE 69227347D1
- Authority
- DE
- Germany
- Prior art keywords
- antagonists
- amylin
- screening procedures
- amylin agonists
- receptors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/670,231 US5264372A (en) | 1991-03-15 | 1991-03-15 | Receptor-based screening methods for amylin agonists and antagonists |
PCT/US1992/002125 WO1992016845A1 (en) | 1991-03-15 | 1992-03-13 | Receptor-based screening methods for amylin agonists and antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69227347D1 true DE69227347D1 (de) | 1998-11-26 |
DE69227347T2 DE69227347T2 (de) | 1999-03-18 |
Family
ID=24689539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69227347T Expired - Fee Related DE69227347T2 (de) | 1991-03-15 | 1992-03-13 | Auf rezeptorgrundlage arbeitende screening-verfahren für amylin-agonisten und- antagonisten |
Country Status (13)
Country | Link |
---|---|
US (1) | US5264372A (de) |
EP (1) | EP0529065B1 (de) |
JP (1) | JPH05508226A (de) |
AT (1) | ATE172540T1 (de) |
AU (1) | AU1663092A (de) |
CA (1) | CA2082929A1 (de) |
DE (1) | DE69227347T2 (de) |
DK (1) | DK0529065T3 (de) |
IL (5) | IL101233A (de) |
MX (1) | MX9201113A (de) |
TW (1) | TW324064B (de) |
WO (1) | WO1992016845A1 (de) |
ZA (1) | ZA921884B (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5580953A (en) * | 1991-08-14 | 1996-12-03 | Amylin Pharmaceuticals, Inc. | Amylin antagonist peptides and uses therefor |
DE69333683T2 (de) * | 1992-05-15 | 2005-10-27 | Amylin Pharmaceuticals, Inc., San Diego | Antikörper-testbesteck zur bestimmung von amylin |
AU6249594A (en) * | 1993-02-12 | 1994-08-29 | Amylin Pharmaceuticals, Inc. | Mcf-7 binding site assays |
WO1994021665A1 (en) * | 1993-03-24 | 1994-09-29 | Amylin Pharmaceuticals, Inc. | Cloned receptors and methods for screening |
GB9317193D0 (en) * | 1993-08-18 | 1993-10-06 | Zeneca Ltd | Method |
EP0717635B1 (de) * | 1993-09-07 | 2000-11-15 | Amylin Pharmaceuticals, Inc. | Methoden zur regulation der den magen und darm betreffenden motilitaet |
US7115728B1 (en) | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
WO1996031526A1 (en) * | 1995-04-06 | 1996-10-10 | Amylin Pharmaceuticals, Inc. | Anti-obesity agents |
US6143718A (en) | 1995-06-07 | 2000-11-07 | Amylin Pharmaceuticals, Inc. | Treatment of Type II diabetes mellutis with amylin agonists |
US5739106A (en) * | 1995-06-07 | 1998-04-14 | Rink; Timothy J. | Appetite regulating compositions |
ATE417622T1 (de) * | 1996-08-08 | 2009-01-15 | Amylin Pharmaceuticals Inc | Regulation gastrointestinaler beweglichkeit |
US5677279A (en) * | 1996-12-16 | 1997-10-14 | Amylin Pharmaceuticals, Inc. | Methods and compositions for treating pain with amylin or agonists thereof |
AU739020B2 (en) * | 1997-01-07 | 2001-10-04 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the reduction of food intake |
US7101853B2 (en) | 1997-05-06 | 2006-09-05 | Amylin Pharmaceuticals, Inc. | Method for treating or preventing gastritis using amylin or amylin agonists |
US7910548B2 (en) | 1997-06-06 | 2011-03-22 | Amylin Pharmaceuticals, Inc. | Methods for treating obesity |
WO1999005161A1 (en) * | 1997-07-25 | 1999-02-04 | Ligand Pharmaceuticals Incorporated | HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR |
US6936584B1 (en) | 1998-02-13 | 2005-08-30 | Amylin Pharmaceuticals, Inc. | Mixed amylin activity compounds |
CA2329513A1 (en) * | 1998-05-26 | 1999-12-02 | University Of Medicine And Dentistry Of New Jersey | System for reproducing and modulating stability and turnover of rna molecules |
US7399489B2 (en) * | 1999-01-14 | 2008-07-15 | Amylin Pharmaceuticals, Inc. | Exendin analog formulations |
KR20070051948A (ko) | 1999-01-14 | 2007-05-18 | 아밀린 파마슈티칼스, 인크. | 글루카곤 억제용 제약학적 조성물 |
US20030087820A1 (en) * | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
US6924264B1 (en) | 1999-04-30 | 2005-08-02 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
EP1175443A1 (de) | 1999-04-30 | 2002-01-30 | Amylin Pharmaceuticals, Inc. | Modifizierte exendine und exendin agonisten |
EP1194778A2 (de) * | 1999-07-13 | 2002-04-10 | Amylin Pharmaceuticals, Inc. | Verwendung der area postrema zur identifizierung von therapeutischen verbindungen |
AU2002218218A1 (en) * | 2000-10-10 | 2002-04-22 | Austrian Nordic Biotherapeutics Ag | A novel system for the evaluation of the activity and/or specificity of a viral component |
US20040005997A1 (en) * | 2002-06-27 | 2004-01-08 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass of function using amylin receptors |
WO2004014947A1 (en) * | 2002-08-06 | 2004-02-19 | Aventis Pharma Deutschland Gmbh | Method for isolating an intestinal cholesterol binding protein |
WO2004037168A2 (en) * | 2002-10-18 | 2004-05-06 | Amylin Pharmaceuticals, Inc. | Treatment of pancreatitis with amylin |
US20040214180A1 (en) * | 2003-04-28 | 2004-10-28 | Hironori Kobayashi | Method and kit for determining quantity of protein |
US20070275877A1 (en) * | 2003-08-29 | 2007-11-29 | Amylin Pharmaceuticals, Inc. | Methods for Treating or Ameliorating Ghrelin-Associated Diseases and Disorders |
JP2008500281A (ja) * | 2004-02-11 | 2008-01-10 | アミリン・ファーマシューティカルズ,インコーポレイテッド | アミリンファミリーペプチドおよびそれらを作成し使用するための方法 |
US7399744B2 (en) * | 2004-03-04 | 2008-07-15 | Amylin Pharmaceuticals, Inc. | Methods for affecting body composition |
AU2005295043A1 (en) * | 2004-10-08 | 2006-04-20 | Amylin Pharmaceuticals, Inc. | Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them |
DE102004051014A1 (de) * | 2004-10-20 | 2006-04-27 | Rwth Aachen | Chemisch modifizierte Peptidanaloga |
ES2325773T5 (es) | 2004-11-01 | 2014-02-24 | Amylin Pharmaceuticals, Llc. | Tratamiento de la obesidad y de los trastornos relacionados |
US8394765B2 (en) * | 2004-11-01 | 2013-03-12 | Amylin Pharmaceuticals Llc | Methods of treating obesity with two different anti-obesity agents |
US7879572B2 (en) * | 2004-11-12 | 2011-02-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Regulation of F1-ATPase beta subunit cellular location |
DE602006016760D1 (de) | 2005-03-31 | 2010-10-21 | Amylin Pharmaceuticals Inc | Zusammensetzungen und verfahren zur kontrolle, prävention und behandlung von essstörungen |
EP1912666A2 (de) * | 2005-07-22 | 2008-04-23 | Amylin Pharmaceuticals, Inc. | Verwendung von amylin und amylin-agonisten als kardioprotektive oder myoprotektive mittel |
WO2009064298A1 (en) * | 2007-11-14 | 2009-05-22 | Amylin Pharmaceuticals, Inc. | Methods for treating obesity and obesity related diseases and disorders |
US9445992B2 (en) | 2009-11-25 | 2016-09-20 | Arisgen Sa | Mucosal delivery compositions comprising a peptide complexed with a crown compound and/or a counter ion |
US9850302B2 (en) | 2013-07-12 | 2017-12-26 | Prothena Biosciences Limited | Antibodies that recognize IAPP |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4434236A (en) * | 1982-10-20 | 1984-02-28 | E. I. Du Pont De Nemours & Co. | Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue |
WO1989006135A1 (en) * | 1988-01-11 | 1989-07-13 | Amylin Corporation | Treatment of type 2 diabetes mellitus |
DE69022501T2 (de) * | 1989-07-10 | 1996-02-01 | Amylin Pharmaceuticals Inc | Verwendung eines Amylinantagonisten zur Herstellung eines Artzneimittels zur Behandlung von Fettsucht und essentieller Hypertonie und damit zusammenhängenden Krankheiten. |
-
1991
- 1991-03-15 US US07/670,231 patent/US5264372A/en not_active Expired - Lifetime
-
1992
- 1992-03-13 AT AT92908951T patent/ATE172540T1/de not_active IP Right Cessation
- 1992-03-13 CA CA002082929A patent/CA2082929A1/en not_active Abandoned
- 1992-03-13 WO PCT/US1992/002125 patent/WO1992016845A1/en active IP Right Grant
- 1992-03-13 EP EP92908951A patent/EP0529065B1/de not_active Expired - Lifetime
- 1992-03-13 AU AU16630/92A patent/AU1663092A/en not_active Abandoned
- 1992-03-13 DK DK92908951T patent/DK0529065T3/da active
- 1992-03-13 MX MX9201113A patent/MX9201113A/es unknown
- 1992-03-13 TW TW081101911A patent/TW324064B/zh not_active IP Right Cessation
- 1992-03-13 ZA ZA921884A patent/ZA921884B/xx unknown
- 1992-03-13 JP JP92508815A patent/JPH05508226A/ja active Pending
- 1992-03-13 DE DE69227347T patent/DE69227347T2/de not_active Expired - Fee Related
- 1992-03-15 IL IL101233A patent/IL101233A/xx not_active IP Right Cessation
- 1992-03-15 IL IL12008192A patent/IL120081A/en not_active IP Right Cessation
- 1992-03-15 IL IL12008292A patent/IL120082A/en not_active IP Right Cessation
-
1997
- 1997-01-27 IL IL12008197A patent/IL120081A0/xx unknown
- 1997-01-27 IL IL12008297A patent/IL120082A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0529065B1 (de) | 1998-10-21 |
EP0529065A4 (en) | 1993-10-20 |
DK0529065T3 (da) | 1999-06-28 |
TW324064B (en) | 1998-01-01 |
IL120081A0 (en) | 1997-04-15 |
WO1992016845A1 (en) | 1992-10-01 |
EP0529065A1 (de) | 1993-03-03 |
IL101233A (en) | 1997-04-15 |
DE69227347T2 (de) | 1999-03-18 |
IL120082A0 (en) | 1997-04-15 |
AU1663092A (en) | 1992-10-21 |
CA2082929A1 (en) | 1992-09-16 |
US5264372A (en) | 1993-11-23 |
IL101233A0 (en) | 1992-11-15 |
JPH05508226A (ja) | 1993-11-18 |
MX9201113A (es) | 1992-10-01 |
IL120082A (en) | 1998-12-27 |
ATE172540T1 (de) | 1998-11-15 |
ZA921884B (en) | 1993-08-03 |
IL120081A (en) | 1998-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |