DE69221648T2 - Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin - Google Patents

Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin

Info

Publication number
DE69221648T2
DE69221648T2 DE69221648T DE69221648T DE69221648T2 DE 69221648 T2 DE69221648 T2 DE 69221648T2 DE 69221648 T DE69221648 T DE 69221648T DE 69221648 T DE69221648 T DE 69221648T DE 69221648 T2 DE69221648 T2 DE 69221648T2
Authority
DE
Germany
Prior art keywords
phenothiazine
direct
site
procedure
regioselective functionalization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69221648T
Other languages
English (en)
Other versions
DE69221648D1 (de
Inventor
Claudio Giordano
Maurizio Paiocchi
Paolo Cavalleri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Publication of DE69221648D1 publication Critical patent/DE69221648D1/de
Application granted granted Critical
Publication of DE69221648T2 publication Critical patent/DE69221648T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/30—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with acyl radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
DE69221648T 1991-02-14 1992-02-05 Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin Expired - Fee Related DE69221648T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910379A IT1244742B (it) 1991-02-14 1991-02-14 Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina

Publications (2)

Publication Number Publication Date
DE69221648D1 DE69221648D1 (de) 1997-09-25
DE69221648T2 true DE69221648T2 (de) 1998-03-26

Family

ID=11358569

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69221648T Expired - Fee Related DE69221648T2 (de) 1991-02-14 1992-02-05 Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin

Country Status (7)

Country Link
US (1) US5362871A (de)
EP (1) EP0499126B1 (de)
JP (1) JP3089373B2 (de)
AT (1) ATE157091T1 (de)
DE (1) DE69221648T2 (de)
ES (1) ES2107473T3 (de)
IT (1) IT1244742B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284279B1 (en) * 1999-12-03 2001-09-04 Avecia, Inc. Phenothiazine in prill form and method for making the same
DE10032137B4 (de) 2000-07-01 2009-04-02 Allessachemie Gmbh Verfahren zur Herstellung von Phenothiazin-Granulat mit verbesserten Eigenschaften
JP2014522396A (ja) 2011-05-27 2014-09-04 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション 置換２−ベンジリデン−２Ｈ−ベンゾ［ｂ］［１，４］チアジン−３（４Ｈ）−オン、その誘導体及びその治療上の使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205635A1 (es) * 1974-01-22 1976-05-21 Rhone Poulenc Ind Procedimiento para preparar nuevos derivados de la (((hidroxi-2 etil)-4-piperidino) -3 propil) -10 fenotiazina
US4578379A (en) * 1980-05-30 1986-03-25 University Of Georgia Research Foundation, Inc. Use of phenothiazine 5-oxide drugs as vaginal contraceptives
IT1237209B (it) * 1989-12-21 1993-05-27 Zambon Spa Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina
EP0451675B1 (de) * 1990-04-09 1995-11-02 ZAMBON GROUP S.p.A. Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin

Also Published As

Publication number Publication date
DE69221648D1 (de) 1997-09-25
EP0499126A2 (de) 1992-08-19
EP0499126B1 (de) 1997-08-20
ES2107473T3 (es) 1997-12-01
EP0499126A3 (en) 1992-10-21
US5362871A (en) 1994-11-08
ITMI910379A1 (it) 1992-08-14
ATE157091T1 (de) 1997-09-15
IT1244742B (it) 1994-08-08
JPH0586042A (ja) 1993-04-06
JP3089373B2 (ja) 2000-09-18
ITMI910379A0 (it) 1991-02-14

Similar Documents

Publication Publication Date Title
DE68918191T2 (de) Verfahren zur Lactonisierung von Mevinsäuren und deren Analogen.
BE876715A (fr) Moyen d'apporter des soins aux ongles de doigts
DE3855399D1 (de) Verfahren zur Justierung von zwei Teilen eines Feldhäckslers
DK538888A (da) Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat
DE69427955D1 (de) Verfahren zur Herstellung von 2,2-Difluorketensilylacetalen und alpha,alpha-Difluor-beta -Silyloxy-1,3-Dioxolan-4-Propansäureestern
DE69221648D1 (de) Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin
DE69114166D1 (de) Verfahren zur direkten und regioselektiven Funktionalisierung in Stelle 2 von Phenothiazin.
DE69108616D1 (de) 3.3'-Dithiobis (Propionsäuren) und Estern davon.
DE69001107D1 (de) Sauerstoff- oder schwefelsubstituierte fettsaeureanaloga zur behandlung retroviraler infektionen.
DE69115090T2 (de) Verfahren zur Herstellung von Fluormethyl-substituierten Pyridin-carbodithioaten.
FR2588448B1 (fr) Composition fongicide a base d'un derive de l'acide phoshoreux et de pyroxyfur
FR2610176B1 (fr) Machine pour le nettoyage et le calibrage de l'ail et autres plantes a bulbe
DE69107546D1 (de) Verfahren zur Herstellung von Insektiziden, Akariziden und Nematiziden-2-Aryl-5-(trifluormethyl)-Pyrrolen.
DE69120567D1 (de) Verfahren zur Herstellung von Fluormethyl-substituierter Piperidin-Carbodithioaten
DE69207874D1 (de) Verfahren zur Herstellung eines Carbonsäureesters und von Formamid
DE69028383T2 (de) Schaltung zur automatischen Regelung des Weiss- und Schwarzabgleiches und deren Verfahren
FR2616441B1 (fr) Procede de preparation d'additifs surbases et compositions renfermant lesdits additifs
IT1203850B (it) Procedimento e impianto per congiungere due estremita' di filo mediante intracciatura
IT1240748B (it) Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina
BE878128A (fr) Compositions a base d'hydroxybenzophenones et procede de stabilisation de ces hydroxybenzophenones
DE69227156T2 (de) Verfahren zur Kultivierung von Bupleurum Falcatum
ATE85323T1 (de) Carbamatderivate und verfahren zu ihrer herstellung.
FI890178A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten keteeniditioasetaalijohdannaisten valmistamiseksi
DE69114741D1 (de) Verfahren zur Herstellung von Fluoromethyl-substituierten Pyridindicarboxylaten.
ATE68175T1 (de) Verfahren zur herstellung von l,l oder d,d oder racemat n6 benzyloxycarbonyl 2,6 diaminopimelinsaeuremonoamid.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee