DE69221306D1 - Methode zur photometrischen (in vitro) bestimmung des gehaltes eines analyts in einer probe - Google Patents
Methode zur photometrischen (in vitro) bestimmung des gehaltes eines analyts in einer probeInfo
- Publication number
- DE69221306D1 DE69221306D1 DE69221306T DE69221306T DE69221306D1 DE 69221306 D1 DE69221306 D1 DE 69221306D1 DE 69221306 T DE69221306 T DE 69221306T DE 69221306 T DE69221306 T DE 69221306T DE 69221306 D1 DE69221306 D1 DE 69221306D1
- Authority
- DE
- Germany
- Prior art keywords
- radiation
- measuring chamber
- pct
- path length
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000338 in vitro Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000005855 radiation Effects 0.000 abstract 12
- 239000012491 analyte Substances 0.000 abstract 3
- 230000003287 optical effect Effects 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/036—Cuvette constructions transformable, modifiable
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0364—Cuvette constructions flexible, compressible
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N2021/3129—Determining multicomponents by multiwavelength light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1062—General features of the devices using the transfer device for another function for testing the liquid while it is in the transfer device
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/066—Modifiable path; multiple paths in one sample
- G01N2201/0662—Comparing measurements on two or more paths in one sample
Landscapes
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Optical Measuring Cells (AREA)
- Paper (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK161391A DK167942B1 (da) | 1991-09-19 | 1991-09-19 | Fremgangsmaade, apparat og maalekammerenhed ved fotometrisk in vitro bestemmelse af indholdet af en analyt i en proeve ved maaling direkte paa proeven |
PCT/DK1992/000280 WO1993006456A1 (en) | 1991-09-19 | 1992-09-17 | Method of photometric in vitro determination of the content of an analyte in a sample |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69221306D1 true DE69221306D1 (de) | 1997-09-04 |
DE69221306T2 DE69221306T2 (de) | 1998-01-08 |
Family
ID=8106547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69221306T Expired - Fee Related DE69221306T2 (de) | 1991-09-19 | 1992-09-17 | Methode zur photometrischen (in vitro) bestimmung des gehaltes eines analyts in einer probe |
Country Status (8)
Country | Link |
---|---|
US (1) | US5371020A (de) |
EP (1) | EP0605598B1 (de) |
JP (1) | JP2978565B2 (de) |
AT (1) | ATE156265T1 (de) |
AU (1) | AU2671692A (de) |
DE (1) | DE69221306T2 (de) |
DK (2) | DK167942B1 (de) |
WO (1) | WO1993006456A1 (de) |
Families Citing this family (80)
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US5351686A (en) * | 1990-10-06 | 1994-10-04 | In-Line Diagnostics Corporation | Disposable extracorporeal conduit for blood constituent monitoring |
US6725072B2 (en) | 1990-10-06 | 2004-04-20 | Hema Metrics, Inc. | Sensor for transcutaneous measurement of vascular access blood flow |
US6246894B1 (en) | 1993-02-01 | 2001-06-12 | In-Line Diagnostics Corporation | System and method for measuring blood urea nitrogen, blood osmolarity, plasma free hemoglobin and tissue water content |
US5550630A (en) * | 1993-03-19 | 1996-08-27 | The United States Of America As Represented By The Secretary Of Agriculture | Spectrophotometric method for structural analysis of organic compounds, polymers, nucleotides and peptides |
DE4405375C2 (de) * | 1994-02-19 | 1996-07-25 | Fritz Nerbe Nachfolger Juergen | Mikrotiterplatte |
AT400639B (de) * | 1994-07-18 | 1996-02-26 | Avl Verbrennungskraft Messtech | Verfahren zur bestimmung der konzentration c eines in einer trägersubstanz homogen verteilten absorbens |
US5510621A (en) * | 1994-10-03 | 1996-04-23 | Optical Solutions, Inc. | Apparatus and method for measuring components in a bag |
DE19520446A1 (de) * | 1995-06-03 | 1996-12-05 | Boehringer Mannheim Gmbh | Probenträger für die Infrarot-Transmissionsspektroskopie |
DK0901634T3 (da) * | 1996-05-30 | 2002-06-10 | Radiometer Medical As | System til bestemmelse af mindst en parameter i mindst en prøve af en fysiologisk væske samt en kassette |
KR100253914B1 (ko) * | 1997-12-20 | 2000-04-15 | 윤덕용 | 광투과경로길이조절이가능한밀폐형온라인측정장치 |
US6804543B2 (en) | 1998-02-05 | 2004-10-12 | Hema Metrics, Inc. | Sensor for transcutaneous measurement of vascular access blood flow |
US6246474B1 (en) | 1998-04-29 | 2001-06-12 | Particle Measuring Systems, Inc. | Method and apparatus for measurement of particle size distribution in substantially opaque slurries |
WO1999058954A1 (en) * | 1998-05-13 | 1999-11-18 | Bayer Corporation | Optical spectroscopy sample cell |
NZ511560A (en) | 1998-11-05 | 2002-11-26 | Chemometec As | A method for the assessment of particles and a system and a device for use in the method |
US6458326B1 (en) | 1999-11-24 | 2002-10-01 | Home Diagnostics, Inc. | Protective test strip platform |
US6746407B2 (en) | 2000-12-29 | 2004-06-08 | Hema Metrics, Inc. | Method of measuring transcutaneous access blood flow |
US6525330B2 (en) | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
US7016087B2 (en) * | 2001-08-08 | 2006-03-21 | Becton Dickinson And Company | Photon efficient scanner |
US6678542B2 (en) * | 2001-08-16 | 2004-01-13 | Optiscan Biomedical Corp. | Calibrator configured for use with noninvasive analyte-concentration monitor and employing traditional measurements |
FR2829286B1 (fr) * | 2001-09-03 | 2008-04-04 | Ge Med Sys Global Tech Co Llc | Dispositif et procede d'emission de rayons x |
US6989891B2 (en) | 2001-11-08 | 2006-01-24 | Optiscan Biomedical Corporation | Device and method for in vitro determination of analyte concentrations within body fluids |
US7061593B2 (en) * | 2001-11-08 | 2006-06-13 | Optiscan Biomedical Corp. | Device and method for in vitro determination of analyte concentrations within body fluids |
US6958809B2 (en) | 2001-11-08 | 2005-10-25 | Optiscan Biomedical Corporation | Reagent-less whole-blood glucose meter |
US7050157B2 (en) * | 2001-11-08 | 2006-05-23 | Optiscan Biomedical Corp. | Reagent-less whole-blood glucose meter |
GB0223546D0 (en) * | 2002-10-10 | 2002-11-20 | Council Cent Lab Res Councils | Sample cell |
US6983177B2 (en) * | 2003-01-06 | 2006-01-03 | Optiscan Biomedical Corporation | Layered spectroscopic sample element with microporous membrane |
US20040132168A1 (en) * | 2003-01-06 | 2004-07-08 | Peter Rule | Sample element for reagentless whole blood glucose meter |
US20040131088A1 (en) * | 2003-01-08 | 2004-07-08 | Adtran, Inc. | Shared T1/E1 signaling bit processor |
US7271912B2 (en) | 2003-04-15 | 2007-09-18 | Optiscan Biomedical Corporation | Method of determining analyte concentration in a sample using infrared transmission data |
AU2004230531A1 (en) * | 2003-04-15 | 2004-10-28 | Optiscan Biomedical Corporation | Sample element qualification |
CA2522485A1 (en) * | 2003-04-15 | 2004-10-28 | Optiscan Biomedical Corporation | Dual measurement analyte detection system |
US20050037384A1 (en) * | 2003-04-15 | 2005-02-17 | Braig James R. | Analyte detection system |
US20050038674A1 (en) * | 2003-04-15 | 2005-02-17 | Braig James R. | System and method for managing a chronic medical condition |
US20050106749A1 (en) * | 2003-04-15 | 2005-05-19 | Braig James R. | Sample element for use in material analysis |
CA2542897A1 (en) | 2003-10-30 | 2005-05-12 | Bayer Healthcare Llc | Optical cuvette with platform-and-well construction |
WO2005043133A1 (en) * | 2003-10-30 | 2005-05-12 | Bayer Healthcare Llc | Formats for optical analysis and methods of manufacturing the same |
CA2563425A1 (en) * | 2004-04-19 | 2005-10-27 | Trojan Technologies Inc. | Optical radiation sensor system and method for measuring radiation transmittance of a fluid |
WO2005111580A1 (en) * | 2004-05-07 | 2005-11-24 | Optiscan Biomedical Corporation | Sample element with fringing-reduction capabilities |
US7763454B2 (en) | 2004-07-09 | 2010-07-27 | Church & Dwight Co., Inc. | Electronic analyte assaying device |
US20060030790A1 (en) * | 2004-08-06 | 2006-02-09 | Braig James R | Sample element with barrier material and vacuum |
NZ554780A (en) * | 2004-12-02 | 2010-01-29 | Foss Analytical As | Spectrophotometer |
DE102004059704B4 (de) * | 2004-12-10 | 2012-07-05 | Scieva Gmbh | Spektroskopischer Nachweis anorganischer, organischer oder biologischer Stoffe |
US8251907B2 (en) | 2005-02-14 | 2012-08-28 | Optiscan Biomedical Corporation | System and method for determining a treatment dose for a patient |
US7722537B2 (en) | 2005-02-14 | 2010-05-25 | Optiscan Biomedical Corp. | Method and apparatus for detection of multiple analytes |
US20060194325A1 (en) * | 2005-02-14 | 2006-08-31 | Gable Jennifer H | Fluid handling cassette with a fluid control interface |
US20070030482A1 (en) * | 2005-08-08 | 2007-02-08 | Zhenghua Ji | Spectrophotometer with adjustable light pathlength |
US9561001B2 (en) | 2005-10-06 | 2017-02-07 | Optiscan Biomedical Corporation | Fluid handling cassette system for body fluid analyzer |
DE102006038271A1 (de) * | 2006-08-11 | 2008-02-14 | Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh | Sensorvorrichtung mit strukturierter Durchflusszelle |
DE102007019695B4 (de) * | 2007-04-24 | 2009-08-13 | Analytik Jena Ag | Küvette für die optische Analyse kleiner Volumina |
US8597190B2 (en) | 2007-05-18 | 2013-12-03 | Optiscan Biomedical Corporation | Monitoring systems and methods with fast initialization |
EP2257784B1 (de) * | 2008-03-21 | 2012-09-12 | Eppendorf Ag | Küvette zur optischen Untersuchung kleiner Flüssigkeitsmengen |
DE102008027085B4 (de) * | 2008-06-05 | 2010-07-15 | Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V. | Vorrichtung zur Analyse einer flüssigen Probe sowie Verfahren zur Analytbestimmung in einem Dialysat mit einer solchen Vorrichtung |
US7961310B1 (en) * | 2008-07-09 | 2011-06-14 | Durasens, LLC | Transmission liquid flow cell with increased internal flow rates |
US9370324B2 (en) | 2008-11-05 | 2016-06-21 | Fresenius Medical Care Holdings, Inc. | Hemodialysis patient data acquisition, management and analysis system |
US10475529B2 (en) | 2011-07-19 | 2019-11-12 | Optiscan Biomedical Corporation | Method and apparatus for analyte measurements using calibration sets |
US9554742B2 (en) | 2009-07-20 | 2017-01-31 | Optiscan Biomedical Corporation | Fluid analysis system |
WO2011011462A1 (en) | 2009-07-20 | 2011-01-27 | Optiscan Biomedical Corporation | Adjustable connector and dead space reduction |
WO2011156522A1 (en) | 2010-06-09 | 2011-12-15 | Optiscan Biomedical Corporation | Measuring analytes in a fluid sample drawn from a patient |
US8333724B2 (en) * | 2010-09-07 | 2012-12-18 | Fresenius Medical Care Holdings, Inc. | Low flow optical blood chamber |
US8743354B2 (en) | 2010-09-07 | 2014-06-03 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
US8517968B2 (en) | 2011-02-25 | 2013-08-27 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
US9194792B2 (en) * | 2010-09-07 | 2015-11-24 | Fresenius Medical Care Holdings, Inc. | Blood chamber for an optical blood monitoring system |
WO2012068416A1 (en) | 2010-11-17 | 2012-05-24 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
US9173988B2 (en) | 2010-11-17 | 2015-11-03 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
DE102011013002C5 (de) * | 2011-03-04 | 2020-12-17 | Optek-Danulat Gmbh | Durchströmbare Messzelle |
WO2013006716A1 (en) | 2011-07-06 | 2013-01-10 | Optiscan Biomedical Corporation | Sample cell for fluid analysis system |
USD725261S1 (en) | 2012-02-24 | 2015-03-24 | Fresenius Medical Care Holdings, Inc. | Blood flow chamber |
EP2936118B1 (de) * | 2012-12-20 | 2023-06-21 | Radiometer Medical ApS | Vorrichtung zum nachweis der konzentration einer komponente in einer probe |
JP6246793B2 (ja) * | 2013-04-18 | 2017-12-13 | ニプロ株式会社 | 流体濃度測定装置 |
EP3208603B1 (de) * | 2013-05-27 | 2019-10-02 | GasPorOx AB | System und verfahren zur bestimmung einer konzentration eines gases in einem behälter |
DE102013011495A1 (de) * | 2013-07-02 | 2015-01-08 | Laser- Und Medizin-Technologie Gmbh, Berlin | Verfahren zur Ermittlung der Konzentration eines Stoffes in einem verformbaren Behälter |
USD799031S1 (en) | 2015-09-09 | 2017-10-03 | Fresenius Medical Care Holdings, Inc. | Blood flow chamber with directional arrow |
EP3199937A1 (de) * | 2016-01-28 | 2017-08-02 | Minitüb GmbH | Zählfach und verfahren zur probenanalyse |
EP4067869B1 (de) * | 2016-02-04 | 2024-01-10 | Nova Biomedical Corporation | Eine optische komponentengruppe zur verwendung in einem spektrometermodul |
CN109477788B (zh) * | 2016-04-08 | 2022-04-22 | 维里菲有限公司 | 用于分光光度法的样品容器 |
WO2018196937A1 (en) * | 2017-04-28 | 2018-11-01 | Q-Interline A/S | A sampling pipette and cuvette, a method of carrying out spectroscopy and a device |
WO2018204290A1 (en) | 2017-05-02 | 2018-11-08 | Ping Lin | Sample holder for use in infrared spectroscopy |
EP4143294A1 (de) | 2020-04-28 | 2023-03-08 | Siemens Healthcare Diagnostics, Inc. | Vorrichtungen und verfahren zur akustophoretischen lyse |
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US3740156A (en) * | 1971-08-11 | 1973-06-19 | Exxon Research Engineering Co | Photometric analyzer sampling cell |
US3810695A (en) * | 1972-12-14 | 1974-05-14 | Gam Rad | Fluid analyzer with variable light path |
US4509522A (en) * | 1981-12-15 | 1985-04-09 | The United States Of America As Represented By The Secretary Of The Navy | Infrared optical measurement of blood gas concentrations and fiber optic catheter |
GB2160646B (en) * | 1984-05-18 | 1988-05-05 | Univ London | Method for determining the concentration of a gas |
DK282085D0 (da) * | 1985-06-21 | 1985-06-21 | Radiometer As | Fremgangsmaade og apparat til bestemmelse af blodkomponenter |
US4762798A (en) * | 1985-12-31 | 1988-08-09 | Marshall Diagnostics, Inc. | Device and method for determining a characteristic of a fluid sample |
US4800886A (en) * | 1986-07-14 | 1989-01-31 | C. R. Bard, Inc. | Sensor for measuring the concentration of a gaseous component in a fluid by absorption |
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US4786171A (en) * | 1986-07-29 | 1988-11-22 | Guided Wave, Inc. | Spectral analysis apparatus and method |
WO1989001144A1 (en) * | 1987-07-24 | 1989-02-09 | Terumo Kabushiki Kaisha | Apparatus for measuring concentration and oxygen saturation of hemoglobin |
DK163194C (da) * | 1988-12-22 | 1992-06-22 | Radiometer As | Fremgangsmaade ved fotometrisk in vitro bestemmelse af en blodgasparameter i en blodproeve |
DE3838371A1 (de) * | 1988-11-11 | 1990-05-17 | Hench Automatik App Masch | Messzelle zur spektralanalyse von stroemenden medien, insbesondere kunststoffschmelzen |
DE68902738T2 (de) * | 1989-05-23 | 1993-01-28 | Biosensors Technology Inc | Verfahren zur bestimmung mittels strahlungsabsorption von substanzen in absorbierenden und streuenden matrixmaterialien. |
US4980551A (en) * | 1990-01-05 | 1990-12-25 | National Research Council Canada Conseil National De Recherches Canada | Non-pressure-dependancy infrared absorption spectra recording, sample cell |
US5168367A (en) * | 1991-01-16 | 1992-12-01 | Rourke Patrick E O | Variable path length spectrophotometric probe |
-
1991
- 1991-09-17 US US08/050,100 patent/US5371020A/en not_active Expired - Lifetime
- 1991-09-19 DK DK161391A patent/DK167942B1/da not_active IP Right Cessation
-
1992
- 1992-09-17 DK DK92920833.8T patent/DK0605598T3/da active
- 1992-09-17 JP JP5505707A patent/JP2978565B2/ja not_active Expired - Fee Related
- 1992-09-17 EP EP92920833A patent/EP0605598B1/de not_active Expired - Lifetime
- 1992-09-17 WO PCT/DK1992/000280 patent/WO1993006456A1/en active IP Right Grant
- 1992-09-17 AU AU26716/92A patent/AU2671692A/en not_active Abandoned
- 1992-09-17 AT AT92920833T patent/ATE156265T1/de not_active IP Right Cessation
- 1992-09-17 DE DE69221306T patent/DE69221306T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0605598B1 (de) | 1997-07-30 |
AU2671692A (en) | 1993-04-27 |
DK167942B1 (da) | 1994-01-03 |
JPH07500904A (ja) | 1995-01-26 |
WO1993006456A1 (en) | 1993-04-01 |
DE69221306T2 (de) | 1998-01-08 |
DK161391A (da) | 1993-03-20 |
DK0605598T3 (da) | 1997-12-29 |
JP2978565B2 (ja) | 1999-11-15 |
ATE156265T1 (de) | 1997-08-15 |
US5371020A (en) | 1994-12-06 |
DK161391D0 (da) | 1991-09-19 |
EP0605598A1 (de) | 1994-07-13 |
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