DE69210675T2 - 3-Aryloxazolidinonderivate, Verfahren zu ihrer Herstellung und ihre Anwendung in der Heilkunde - Google Patents
3-Aryloxazolidinonderivate, Verfahren zu ihrer Herstellung und ihre Anwendung in der HeilkundeInfo
- Publication number
- DE69210675T2 DE69210675T2 DE69210675T DE69210675T DE69210675T2 DE 69210675 T2 DE69210675 T2 DE 69210675T2 DE 69210675 T DE69210675 T DE 69210675T DE 69210675 T DE69210675 T DE 69210675T DE 69210675 T2 DE69210675 T2 DE 69210675T2
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- denotes
- alkyl
- forms
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 125000000815 N-oxide group Chemical group 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9104641A FR2675504B1 (fr) | 1991-04-16 | 1991-04-16 | Derives d'aryl-3 oxazolidinone, leur procede de preparation et leur application en therapeutique. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69210675D1 DE69210675D1 (de) | 1996-06-20 |
| DE69210675T2 true DE69210675T2 (de) | 1996-11-28 |
Family
ID=9411887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69210675T Expired - Fee Related DE69210675T2 (de) | 1991-04-16 | 1992-03-18 | 3-Aryloxazolidinonderivate, Verfahren zu ihrer Herstellung und ihre Anwendung in der Heilkunde |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5264443A (de) |
| EP (1) | EP0511031B1 (de) |
| JP (1) | JPH05112542A (de) |
| KR (1) | KR920019766A (de) |
| AT (1) | ATE138059T1 (de) |
| AU (1) | AU647909B2 (de) |
| CA (1) | CA2065962A1 (de) |
| DE (1) | DE69210675T2 (de) |
| DK (1) | DK0511031T3 (de) |
| ES (1) | ES2087474T3 (de) |
| FR (1) | FR2675504B1 (de) |
| GR (1) | GR3020546T3 (de) |
| NZ (1) | NZ242351A (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2715155B1 (fr) * | 1994-01-19 | 1996-07-26 | Mayoly Spindler | Inhibiteurs de la monoamine oxydase B et leurs procédés de préparation. |
| ES2123889T3 (es) | 1994-11-02 | 1999-01-16 | Merck Patent Gmbh | Antagonistas de receptores de adhesion. |
| US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
| CN1798557A (zh) * | 2003-05-29 | 2006-07-05 | 协和梅迪克斯株式会社 | 抗抑郁剂或者抗抑郁用饮食品 |
| MX2010014461A (es) * | 2008-06-24 | 2011-04-28 | Valeant Pharmaceuticals Int | Derivados de benciloxi anilida utiles como moduladores de canales de potasio. |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CN113993523A (zh) | 2019-04-17 | 2022-01-28 | 指南针探路者有限公司 | 用赛洛西宾治疗抑郁症和其他各种病症 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2954381A (en) * | 1958-12-03 | 1960-09-27 | Us Vitamin Pharm Corp | Heteroaryloxazolidinediones |
| US3290326A (en) * | 1963-09-20 | 1966-12-06 | Hoffmann La Roche | Esters of 4-lower alkyl-5-oxazole-car-bamic acid and intermediates therefor |
| US4133675A (en) * | 1976-07-23 | 1979-01-09 | Ciba-Geigy Corporation | Pyridyloxy-phenoxy-alkanecarboxylic acid derivatives which are effective as herbicides and as agents regulating plant growth |
| US4348393A (en) * | 1978-06-09 | 1982-09-07 | Delalande S.A. | N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones |
| FR2506769A2 (fr) * | 1978-06-09 | 1982-12-03 | Delalande Sa | Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique |
| CA1171865A (en) * | 1980-06-04 | 1984-07-31 | Alain Lacour | N-aryl azolone derivatives, the process for preparing the same and their application in therapeutics |
| FR2608604B1 (fr) * | 1986-12-19 | 1989-04-28 | Delalande Sa | Derives 5-hydroxyethyles de l'oxazolidinone-2, leurs procedes de preparation et leurs applications en therapeutique |
| FR2653017B1 (fr) * | 1989-10-17 | 1995-05-05 | Delalande Sa | Derives d'aryl-3 oxazolidinone-2, leur procede de preparation et leur application en therapeutique. |
-
1991
- 1991-04-16 FR FR9104641A patent/FR2675504B1/fr not_active Expired - Fee Related
-
1992
- 1992-03-18 EP EP92400721A patent/EP0511031B1/de not_active Expired - Lifetime
- 1992-03-18 DK DK92400721.4T patent/DK0511031T3/da active
- 1992-03-18 ES ES92400721T patent/ES2087474T3/es not_active Expired - Lifetime
- 1992-03-18 DE DE69210675T patent/DE69210675T2/de not_active Expired - Fee Related
- 1992-03-18 AT AT92400721T patent/ATE138059T1/de not_active IP Right Cessation
- 1992-04-08 KR KR1019920005842A patent/KR920019766A/ko not_active Application Discontinuation
- 1992-04-09 US US07/865,885 patent/US5264443A/en not_active Expired - Fee Related
- 1992-04-14 NZ NZ242351A patent/NZ242351A/xx unknown
- 1992-04-14 CA CA002065962A patent/CA2065962A1/en not_active Abandoned
- 1992-04-15 AU AU14910/92A patent/AU647909B2/en not_active Ceased
- 1992-04-15 JP JP4095189A patent/JPH05112542A/ja active Pending
-
1996
- 1996-07-16 GR GR960401914T patent/GR3020546T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2675504A1 (fr) | 1992-10-23 |
| ES2087474T3 (es) | 1996-07-16 |
| EP0511031B1 (de) | 1996-05-15 |
| US5264443A (en) | 1993-11-23 |
| FR2675504B1 (fr) | 1995-01-27 |
| JPH05112542A (ja) | 1993-05-07 |
| DE69210675D1 (de) | 1996-06-20 |
| KR920019766A (ko) | 1992-11-19 |
| GR3020546T3 (en) | 1996-10-31 |
| DK0511031T3 (da) | 1996-09-30 |
| NZ242351A (en) | 1993-08-26 |
| ATE138059T1 (de) | 1996-06-15 |
| CA2065962A1 (en) | 1992-10-17 |
| AU647909B2 (en) | 1994-03-31 |
| AU1491092A (en) | 1992-10-22 |
| EP0511031A1 (de) | 1992-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |