DE69127313T2 - Subklasse von menschlichen Vorläuferzellen - Google Patents
Subklasse von menschlichen VorläuferzellenInfo
- Publication number
- DE69127313T2 DE69127313T2 DE69127313T DE69127313T DE69127313T2 DE 69127313 T2 DE69127313 T2 DE 69127313T2 DE 69127313 T DE69127313 T DE 69127313T DE 69127313 T DE69127313 T DE 69127313T DE 69127313 T2 DE69127313 T2 DE 69127313T2
- Authority
- DE
- Germany
- Prior art keywords
- subclass
- human progenitor
- progenitor cells
- stem cells
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 3
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 abstract 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 abstract 1
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 abstract 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 abstract 1
- 238000010322 bone marrow transplantation Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000005757 colony formation Effects 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51710190A | 1990-05-01 | 1990-05-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69127313D1 DE69127313D1 (de) | 1997-09-25 |
DE69127313T2 true DE69127313T2 (de) | 1998-01-22 |
Family
ID=24058370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69127313T Expired - Lifetime DE69127313T2 (de) | 1990-05-01 | 1991-05-01 | Subklasse von menschlichen Vorläuferzellen |
Country Status (11)
Country | Link |
---|---|
US (2) | US5622853A (de) |
EP (1) | EP0455482B1 (de) |
JP (1) | JP3070865B2 (de) |
AT (1) | ATE157119T1 (de) |
AU (1) | AU641230B2 (de) |
CA (1) | CA2041258A1 (de) |
DE (1) | DE69127313T2 (de) |
DK (1) | DK0455482T3 (de) |
ES (1) | ES2106763T3 (de) |
GR (1) | GR3024783T3 (de) |
IE (1) | IE911145A1 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571714A (en) | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
US5635386A (en) | 1989-06-15 | 1997-06-03 | The Regents Of The University Of Michigan | Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture |
US5605822A (en) * | 1989-06-15 | 1997-02-25 | The Regents Of The University Of Michigan | Methods, compositions and devices for growing human hematopoietic cells |
US5635387A (en) * | 1990-04-23 | 1997-06-03 | Cellpro, Inc. | Methods and device for culturing human hematopoietic cells and their precursors |
US5840580A (en) * | 1990-05-01 | 1998-11-24 | Becton Dickinson And Company | Phenotypic characterization of the hematopoietic stem cell |
DK0614485T3 (da) * | 1991-10-23 | 2002-10-28 | Nexell Therapeutics Inc | Fremgangsmåde til selektiv formering af CD34 positive celler |
EP0563485A1 (de) * | 1992-03-30 | 1993-10-06 | Schering-Plough | In-vitro-Erzeugung von menschlichen dendritischen Zellen |
US6004807A (en) * | 1992-03-30 | 1999-12-21 | Schering Corporation | In vitro generation of human dendritic cells |
US5436151A (en) * | 1992-04-03 | 1995-07-25 | Regents Of The University Of Minnesota | Method for culturing human hematopoietic stem cells in vitro |
US5460964A (en) * | 1992-04-03 | 1995-10-24 | Regents Of The University Of Minnesota | Method for culturing hematopoietic cells |
DE69309487T2 (de) * | 1992-11-13 | 1997-10-23 | Univ Washington | Peripheralisierung hämatopoietischer stammzellen |
SG86980A1 (en) * | 1992-11-16 | 2002-03-19 | Applied Immunesciences | Pluripotential quiescent stem cell population |
WO1994018991A1 (en) * | 1993-02-19 | 1994-09-01 | Celtrix Pharmaceuticals, Inc. | EXPANSION OF STEM CELLS IN LONG TERM BONE MARROW CULTURES BY NEUTRALIZATION OF TGF-$g(b) |
JPH08509720A (ja) * | 1993-05-03 | 1996-10-15 | ジェネンテク、インコーポレイテッド | 白血球接着阻害 |
US6555324B1 (en) * | 1993-11-04 | 2003-04-29 | Becton Dickinson & Company | Method to distinguish hematopoietic progenitor cells |
EP0662512A3 (de) * | 1993-12-20 | 1997-01-15 | Becton Dickinson Co | Menschliche hämatopoietische Stammzellen. |
US5972703A (en) | 1994-08-12 | 1999-10-26 | The Regents Of The University Of Michigan | Bone precursor cells: compositions and methods |
DE69531432T2 (de) * | 1994-09-23 | 2004-07-29 | Becton Dickinson And Co. | Verfahren zur Unterscheidung von granulomoncytischen Progenitoren in einer Population von CD34+ Zellen |
US5874266A (en) * | 1997-03-27 | 1999-02-23 | Palsson; Bernhard O. | Targeted system for removing tumor cells from cell populations |
AU1457199A (en) | 1997-11-12 | 1999-05-31 | University Of Pittsburgh | Isolation, characterization, and identification of dendritic like cells and methods of using same |
US20020034819A1 (en) | 1998-02-23 | 2002-03-21 | Alan K. Smith | Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses |
US7799324B2 (en) | 2001-12-07 | 2010-09-21 | Geron Corporation | Using undifferentiated embryonic stem cells to control the immune system |
EP2292734A1 (de) | 2001-12-07 | 2011-03-09 | Geron Corporation | Hämatopoietische Zellen aus menschlichen Embryostammzellen |
NZ534205A (en) * | 2001-12-22 | 2006-04-28 | Antibody A 4 | Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins |
WO2004066926A2 (en) | 2003-01-25 | 2004-08-12 | Irm Llc | Methods and compositions for modulating t lymphocytes |
AU2004227205B2 (en) * | 2003-04-08 | 2010-06-10 | Yeda Research And Development Co. Ltd | Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same |
US8940535B2 (en) | 2003-11-04 | 2015-01-27 | University Of Maryland, Baltimore | Stem cell culture medium and method of using said medium and the cells |
EP1851308B1 (de) * | 2005-02-02 | 2013-08-21 | NewSouth Innovations Pty Limited | Gegen ein spezifisches antigen aktivierte cd4+ cd25+ t-zellen |
CA2644922C (en) | 2006-03-07 | 2019-07-23 | Geeta Shroff | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
US8569059B2 (en) | 2006-08-02 | 2013-10-29 | Newsouth Innovations Pty Limited | Method of identifying CD4+ CD25+ T-cells activated to an antigen which express CD8 |
US8710836B2 (en) * | 2008-12-10 | 2014-04-29 | Nanomr, Inc. | NMR, instrumentation, and flow meter/controller continuously detecting MR signals, from continuously flowing sample material |
WO2011008277A2 (en) * | 2009-07-14 | 2011-01-20 | Massachusetts Institute Of Technology | Hematopoietic stromal progenitor cells and uses thereof |
US8841104B2 (en) | 2010-04-21 | 2014-09-23 | Nanomr, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US9428547B2 (en) | 2010-04-21 | 2016-08-30 | Dna Electronics, Inc. | Compositions for isolating a target analyte from a heterogeneous sample |
US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
CN104583006B (zh) | 2012-08-07 | 2017-09-15 | 提爱思科技股份有限公司 | 部件连接结构和交通工具座椅 |
US9434940B2 (en) | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
US9804069B2 (en) | 2012-12-19 | 2017-10-31 | Dnae Group Holdings Limited | Methods for degrading nucleic acid |
CA2927712A1 (en) | 2013-10-24 | 2015-04-30 | Ospedale San Raffaele S.R.L. | Method for the genetic modification of haematopoietic stem and progenitor cells (hspcs) and the use of genetically modified hspcs in gene therapy |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4680383A (en) * | 1979-03-20 | 1987-07-14 | Ortho Pharmaceutical | Monoclonal antibody to human T cells |
US4803262A (en) * | 1979-10-09 | 1989-02-07 | Ortho Pharmaceutical Corporation | Hybrid cell line for producing monoclonal antibody to human cytotoxic and suppressor T cells, antibody, and methods |
US4624925A (en) * | 1979-12-04 | 1986-11-25 | Ortho Pharmaceutical Corporation | Hybrid cell line for producing monoclonal antibody to a human early thymocyte antigens, antibody, and methods |
US4798806A (en) * | 1980-01-08 | 1989-01-17 | Ortho Pharmaceutical Corporation | Compositions and methods using a monoclonal antibody to a human T cell antigen |
US4714680B1 (en) * | 1984-02-06 | 1995-06-27 | Univ Johns Hopkins | Human stem cells |
US4845653A (en) * | 1987-05-07 | 1989-07-04 | Becton, Dickinson And Company | Method of displaying multi-parameter data sets to aid in the analysis of data characteristics |
ATE81724T1 (de) * | 1987-11-09 | 1992-11-15 | Becton Dickinson Co | Verfahren zur analyse haematopoietischer zellen in einer probe. |
US4987086A (en) * | 1987-11-30 | 1991-01-22 | Becton, Dickinson And Company | Method for analysis of subpopulations of cells |
WO1989008114A1 (en) * | 1988-02-25 | 1989-09-08 | The General Hospital Corporation | Rapid immunoselection cloning method |
US5087570A (en) * | 1988-05-10 | 1992-02-11 | Weissman Irving L | Homogeneous mammalian hematopoietic stem cell composition |
US5047321A (en) * | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
US5061620A (en) * | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
-
1991
- 1991-03-14 US US07/669,142 patent/US5622853A/en not_active Expired - Lifetime
- 1991-04-05 IE IE114591A patent/IE911145A1/en unknown
- 1991-04-10 AU AU74293/91A patent/AU641230B2/en not_active Ceased
- 1991-04-25 CA CA002041258A patent/CA2041258A1/en not_active Abandoned
- 1991-05-01 AT AT91303960T patent/ATE157119T1/de not_active IP Right Cessation
- 1991-05-01 DE DE69127313T patent/DE69127313T2/de not_active Expired - Lifetime
- 1991-05-01 DK DK91303960.8T patent/DK0455482T3/da active
- 1991-05-01 ES ES91303960T patent/ES2106763T3/es not_active Expired - Lifetime
- 1991-05-01 JP JP3100164A patent/JP3070865B2/ja not_active Expired - Lifetime
- 1991-05-01 EP EP91303960A patent/EP0455482B1/de not_active Expired - Lifetime
-
1993
- 1993-10-19 US US08/139,293 patent/US5583033A/en not_active Expired - Lifetime
-
1997
- 1997-09-17 GR GR970402407T patent/GR3024783T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0455482A2 (de) | 1991-11-06 |
DE69127313D1 (de) | 1997-09-25 |
ATE157119T1 (de) | 1997-09-15 |
ES2106763T3 (es) | 1997-11-16 |
EP0455482A3 (en) | 1992-09-02 |
US5583033A (en) | 1996-12-10 |
EP0455482B1 (de) | 1997-08-20 |
US5622853A (en) | 1997-04-22 |
AU641230B2 (en) | 1993-09-16 |
GR3024783T3 (en) | 1998-01-30 |
CA2041258A1 (en) | 1991-11-02 |
IE911145A1 (en) | 1991-11-06 |
JPH0576354A (ja) | 1993-03-30 |
JP3070865B2 (ja) | 2000-07-31 |
DK0455482T3 (da) | 1998-04-06 |
AU7429391A (en) | 1991-11-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: MOSELPATENT TRIERPATENT, 54290 TRIER |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: PATENTANWAELTE SERWE & DR. WAGNER, 54290 TRIER |