MY103637A - Neutrophil-activating factor - Google Patents

Neutrophil-activating factor

Info

Publication number
MY103637A
MY103637A MYPI88001306A MYPI19881306A MY103637A MY 103637 A MY103637 A MY 103637A MY PI88001306 A MYPI88001306 A MY PI88001306A MY PI19881306 A MYPI19881306 A MY PI19881306A MY 103637 A MY103637 A MY 103637A
Authority
MY
Malaysia
Prior art keywords
lys
glu
leu
ile
val
Prior art date
Application number
MYPI88001306A
Inventor
James Daldon Lindley Ivan
Peversi Paola
Walz Alfred
Aschauer Heinrich
Original Assignee
Kocher Theodor Inst
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888805070A external-priority patent/GB8805070D0/en
Priority claimed from GB888825258A external-priority patent/GB8825258D0/en
Application filed by Kocher Theodor Inst, Sandoz Ltd filed Critical Kocher Theodor Inst
Publication of MY103637A publication Critical patent/MY103637A/en

Links

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  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

BIOLOGICALLY ACTIVE, PURE NEUTROPHIL-ACTIVATING FACTOR (NAF) IS ISOLATED FROM HUMAN MONOCYTES OR AFTER EXPRESSION OF A SYNTHETIC NAF GENE IN E.COLI. IT HAS THE FOLLOWING AMINO ACID SEQUENCE:SER-ALA-LYS-GLU-LEU-ARG-CYS-GLN-CYS-ILE-LYS-THR-TYR-SER-LYS-PRO-PHE-HIS-PRO-LYS-PHE-ILE-LYS-GLU-LEU-ARG-VAL-ILE-GLU-SER-GLY-PRO-HIS-CYS-ALA-ASN-THR-GLU-ILE-ILE-VAL-LYS-LEU-SER-ASP-GLY-ARG-GLU-LEU-CYS-LEU-ASP-PRO-LYS-GLU-ASN-TRP-VAL-GLN-ARG-VAL-VAL-GLU-LYS-PHE-LEU-LYS-ARGALA-GLU-ASN-SER.THERE ARE THREE FURTHER MINOR VARIANTS WITH LONGER AND SHORTER SEQUENCES. NATURAL AND SYNTHETIC NAF HAVE IDENTICAL STRUCTURE AND BIOLOGICAL PROPERTIES.
MYPI88001306A 1987-11-19 1988-11-17 Neutrophil-activating factor MY103637A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH2705387 1987-11-19
GB888805070A GB8805070D0 (en) 1988-03-03 1988-03-03 Neutrophil-activating factor(naf)
GB888825258A GB8825258D0 (en) 1988-10-28 1988-10-28 Neutrophil-activating factor

Publications (1)

Publication Number Publication Date
MY103637A true MY103637A (en) 1993-08-28

Family

ID=79604027

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI88001306A MY103637A (en) 1987-11-19 1988-11-17 Neutrophil-activating factor

Country Status (1)

Country Link
MY (1) MY103637A (en)

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