DE69126537D1 - (2-thienyl)alkylaminderivate mit nervenschützenden eigenschaften - Google Patents

(2-thienyl)alkylaminderivate mit nervenschützenden eigenschaften

Info

Publication number
DE69126537D1
DE69126537D1 DE69126537T DE69126537T DE69126537D1 DE 69126537 D1 DE69126537 D1 DE 69126537D1 DE 69126537 T DE69126537 T DE 69126537T DE 69126537 T DE69126537 T DE 69126537T DE 69126537 D1 DE69126537 D1 DE 69126537D1
Authority
DE
Germany
Prior art keywords
alkyl
hydrogen
amino
represents hydrogen
represent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69126537T
Other languages
English (en)
Other versions
DE69126537T2 (de
Inventor
Ronald Griffith
Richard Schmiesing
Robert Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/589,963 external-priority patent/US5109017A/en
Application filed by Astra AB filed Critical Astra AB
Publication of DE69126537D1 publication Critical patent/DE69126537D1/de
Application granted granted Critical
Publication of DE69126537T2 publication Critical patent/DE69126537T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69126537T 1990-09-26 1991-09-24 (2-thienyl)alkylaminderivate mit nervenschützenden eigenschaften Expired - Fee Related DE69126537T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58987990A 1990-09-26 1990-09-26
US07/589,963 US5109017A (en) 1990-09-26 1990-09-26 (2-thienyl)alkylamine derivatives having neuroprotective properties
PCT/US1991/006951 WO1992005169A1 (en) 1990-09-26 1991-09-24 (2-thienyl) alkylamine derivatives having neuroprotective properties

Publications (2)

Publication Number Publication Date
DE69126537D1 true DE69126537D1 (de) 1997-07-17
DE69126537T2 DE69126537T2 (de) 1997-10-02

Family

ID=27080687

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69126537T Expired - Fee Related DE69126537T2 (de) 1990-09-26 1991-09-24 (2-thienyl)alkylaminderivate mit nervenschützenden eigenschaften

Country Status (11)

Country Link
EP (1) EP0557305B1 (de)
JP (1) JP3108433B2 (de)
AT (1) ATE154349T1 (de)
DE (1) DE69126537T2 (de)
DK (1) DK0557305T3 (de)
ES (1) ES2103004T3 (de)
GR (1) GR3024553T3 (de)
HU (1) HU211322A9 (de)
IE (1) IE913279A1 (de)
PT (1) PT99050B (de)
WO (1) WO1992005169A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0516978A1 (de) * 1991-05-03 1992-12-09 Hoechst Aktiengesellschaft Enantiomere von substituierten (Aminophenyl)--hetroarylethylaminen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19963175A1 (de) * 1999-12-27 2001-07-12 Gruenenthal Gmbh Verwendung von substituierten 4-Amino-1-phenylbutan-2-ol-Verbindungen als Arzneimittel
DE10025238A1 (de) * 2000-05-22 2001-11-29 Gruenenthal Gmbh Verwendung substituierter 1-Amino-5-phenylpentan-3-ol- und/oder 1-Amino-6-phenylhexan-3-ol- Verbindungen als Arzneimittel
ATE327986T1 (de) * 2001-02-16 2006-06-15 Allelix Neuroscience Inc Thiophen substituierte amin derivate als glyt-1 inhibitoren
DE602004027094D1 (de) 2004-12-31 2010-06-17 Koppert Bv Milbenzusammensetzung, ihre verwendung, verfahren zur aufzucht einer phytoseiiden-raubmilbe, aufzuchtsystem für die aufzucht dieser phytoseiiden-raubmsbekämpfung in einer kultur
MX278547B (es) 2004-12-31 2010-08-30 Koppert Bv Composicion de acaros, uso de la misma metodo para criar el acaro predatorio phytoseiid amblyseius swirskii, sistema de crianza para criar el acaro phytoseiid y metodos para el control biologico de plagas en un cultivo.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86740A (en) * 1987-06-30 1992-11-15 Tanabe Seiyaku Co Thiphene derivatives,their preparation and pharmaceutical compositions containing them
JPS6416778A (en) * 1987-07-09 1989-01-20 Tanabe Seiyaku Co Thiophene derivative
EP0322582A3 (de) * 1987-12-07 1989-09-13 Hoechst-Roussel Pharmaceuticals Incorporated 4-Heteroaryl-1,3-benzodiazepine und 2-substituierte Alpha-(heteroaryl) benzenethanamine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP0346791B1 (de) * 1988-06-14 1994-04-06 G.D. Searle & Co. 1,2-Diarylethylamine zur Behandlung neurotoxischer Verletzungen

Also Published As

Publication number Publication date
GR3024553T3 (en) 1997-12-31
PT99050A (pt) 1992-08-31
PT99050B (pt) 1999-02-26
ATE154349T1 (de) 1997-06-15
EP0557305A1 (de) 1993-09-01
WO1992005169A1 (en) 1992-04-02
HU211322A9 (en) 1995-11-28
JP3108433B2 (ja) 2000-11-13
JPH06501472A (ja) 1994-02-17
IE913279A1 (en) 1992-04-08
DK0557305T3 (da) 1997-09-08
ES2103004T3 (es) 1997-08-16
EP0557305B1 (de) 1997-06-11
DE69126537T2 (de) 1997-10-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee