DE69125992D1 - Verfahren und Kit für Immunoassay - Google Patents

Verfahren und Kit für Immunoassay

Info

Publication number
DE69125992D1
DE69125992D1 DE69125992T DE69125992T DE69125992D1 DE 69125992 D1 DE69125992 D1 DE 69125992D1 DE 69125992 T DE69125992 T DE 69125992T DE 69125992 T DE69125992 T DE 69125992T DE 69125992 D1 DE69125992 D1 DE 69125992D1
Authority
DE
Germany
Prior art keywords
immunoassay
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69125992T
Other languages
English (en)
Other versions
DE69125992T2 (de
Inventor
Kenji Ikeda
Kazuhisa Toyoda
Hideo Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tosoh Corp
Original Assignee
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tosoh Corp filed Critical Tosoh Corp
Publication of DE69125992D1 publication Critical patent/DE69125992D1/de
Application granted granted Critical
Publication of DE69125992T2 publication Critical patent/DE69125992T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE69125992T 1990-09-14 1991-09-13 Verfahren und Kit für Immunoassay Expired - Fee Related DE69125992T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24272190 1990-09-14

Publications (2)

Publication Number Publication Date
DE69125992D1 true DE69125992D1 (de) 1997-06-12
DE69125992T2 DE69125992T2 (de) 1997-08-21

Family

ID=17093260

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125992T Expired - Fee Related DE69125992T2 (de) 1990-09-14 1991-09-13 Verfahren und Kit für Immunoassay

Country Status (3)

Country Link
US (1) US5434088A (de)
EP (1) EP0476545B1 (de)
DE (1) DE69125992T2 (de)

Families Citing this family (38)

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US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
EP0984281B1 (de) * 1991-05-22 2007-01-03 Dade Behring Marburg GmbH Homogenes Testsystem zur Bestimmung eines Analytes
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US20010055581A1 (en) 1994-03-18 2001-12-27 Lawrence Tamarkin Composition and method for delivery of biologically-active factors
DE4421907A1 (de) * 1994-06-24 1996-01-04 Behringwerke Ag Verfahren zur Durchführung eines Immunoassays in einem Mehrphasensystem
US5783453A (en) * 1995-06-29 1998-07-21 Chiron Diagnostics Corporation Non-separation specific binding chemiluminescent assay
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
US6544797B1 (en) * 1997-04-09 2003-04-08 Biosite Diagnostics, Inc. Compositions and methods for inhibiting light-induced inactivation of biological reagents
WO1998047001A1 (en) 1997-04-11 1998-10-22 The University Of New Mexico Modular assembly for reagentless affinity separation and detection of analyte
US6221612B1 (en) * 1997-08-01 2001-04-24 Aurora Biosciences Corporation Photon reducing agents for use in fluorescence assays
US6214563B1 (en) 1997-08-01 2001-04-10 Aurora Biosciences Corporation Photon reducing agents for reducing undesired light emission in assays
US6200762B1 (en) 1997-08-01 2001-03-13 Aurora Biosciences Corporation Photon reducing agents and compositions for fluorescence assays
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
AU9402198A (en) * 1997-09-26 1999-04-23 Becton Dickinson & Company Preparing conjugates using polyethylene glycol linkers
US6407218B1 (en) * 1997-11-10 2002-06-18 Cytimmune Sciences, Inc. Method and compositions for enhancing immune response and for the production of in vitro mabs
US7229841B2 (en) * 2001-04-30 2007-06-12 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
DK1086135T3 (da) * 1998-05-28 2004-06-21 Bayer Healthcare Ag Monoklonalt antistof og assay til detektering af N-terminalt prokollagen (III)-propeptid (PIIINP)
IL141383A (en) * 1999-05-05 2005-11-20 Univ California Sensor containing a polymer for detecting biological agents and methods utilizing the same
US6136268A (en) * 1999-08-17 2000-10-24 Orion Diagnostica Method for luminescence measurements
ATE261583T1 (de) * 1999-09-01 2004-03-15 Invitrogen Corp Photon dämpfer für fluoreszenzassays
WO2002001225A2 (en) * 2000-06-23 2002-01-03 Minerva Biotechnologies Corporation Tandem signaling assay
WO2002050543A2 (en) * 2000-12-19 2002-06-27 Instrumentation Laboratory Co. Free analyte detection system
US7179658B2 (en) * 2001-09-06 2007-02-20 Beckman Coulter, Inc. Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection
US7939283B2 (en) * 2001-11-01 2011-05-10 Fisher Scientific Company L.L.C. Analyte binding turbidity assay
US20050175583A1 (en) 2003-12-02 2005-08-11 Lawrence Tamarkin Methods and compositions for the production of monoclonal antibodies
EP1715971A4 (de) * 2004-01-28 2010-10-13 Cytimmune Sciences Inc Funktionalisierte kolloidale metallzusammensetzungen und verfahren
US7741467B2 (en) 2005-10-05 2010-06-22 Roche Molecular Systems, Inc. Non-fluorescent energy transfer
CN100367034C (zh) * 2005-10-20 2008-02-06 上海交通大学 免疫胶体金粒子荧光淬灭的测量方法
US8841134B2 (en) * 2006-04-10 2014-09-23 Bruker Biospin Corporation Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications
US20110014118A1 (en) * 2007-09-21 2011-01-20 Lawrence Tamarkin Nanotherapeutic colloidal metal compositions and methods
CA2700378A1 (en) * 2007-09-21 2009-03-29 Cytimmune Sciences, Inc. Nanotherapeutic colloidal metal compositions and methods
US7960145B2 (en) * 2007-11-08 2011-06-14 Cytimmune Sciences, Inc. Compositions and methods for generating antibodies
JP5518450B2 (ja) * 2008-12-04 2014-06-11 富士フイルム株式会社 断片化抗体固定化担体及びその製造方法
WO2011057347A1 (en) * 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
CN102401829B (zh) * 2010-09-17 2015-04-29 上海鑫谱生物科技有限公司 一种基于荧光淬灭原理的免疫反应分析方法
US10809250B2 (en) 2015-08-25 2020-10-20 Bio-Rad Laboratories, Inc. Digital immunoassay
CN110441514B (zh) * 2019-06-18 2022-11-29 北京利德曼生化股份有限公司 一种胶乳微球与抗体复合物的制备方法、产品及其应用
CN111721931A (zh) * 2020-06-23 2020-09-29 广州万孚生物技术股份有限公司 一种固相时间分辨荧光免疫标记物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261968A (en) * 1979-05-10 1981-04-14 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
IL64574A (en) * 1981-04-27 1986-01-31 Syva Co Method for determining the presence of an analyte by determination of the amount of fluorescence in competitive protein binding assays
US4654300A (en) * 1982-04-02 1987-03-31 Syntex (U.S.A.) Inc. Fluorescent microbead quenching assay
EP0092344A1 (de) * 1982-04-15 1983-10-26 AMERSHAM INTERNATIONAL plc Testverfahren
US4572901A (en) * 1983-06-23 1986-02-25 Children's Hospital Medical Center Of Northern California Method and composition for protein immobilization
US4777128A (en) * 1986-05-27 1988-10-11 Ethigen Corporation Fluorescence immunoassay involving energy transfer between two fluorophores
CA1308022C (en) * 1988-08-11 1992-09-29 Eleftherios P. Diamandis Multiple fluorescence labelling with europium chelators
ES2032104T3 (es) * 1988-11-15 1993-01-01 H.B.T. Holland Biotechnology B.V. Proceso para la preparacion de coloides.

Also Published As

Publication number Publication date
EP0476545B1 (de) 1997-05-07
US5434088A (en) 1995-07-18
DE69125992T2 (de) 1997-08-21
EP0476545A1 (de) 1992-03-25

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Legal Events

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8339 Ceased/non-payment of the annual fee