DE69125992D1 - Verfahren und Kit für Immunoassay - Google Patents
Verfahren und Kit für ImmunoassayInfo
- Publication number
- DE69125992D1 DE69125992D1 DE69125992T DE69125992T DE69125992D1 DE 69125992 D1 DE69125992 D1 DE 69125992D1 DE 69125992 T DE69125992 T DE 69125992T DE 69125992 T DE69125992 T DE 69125992T DE 69125992 D1 DE69125992 D1 DE 69125992D1
- Authority
- DE
- Germany
- Prior art keywords
- immunoassay
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/969—Multiple layering of reactants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24272190 | 1990-09-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69125992D1 true DE69125992D1 (de) | 1997-06-12 |
DE69125992T2 DE69125992T2 (de) | 1997-08-21 |
Family
ID=17093260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69125992T Expired - Fee Related DE69125992T2 (de) | 1990-09-14 | 1991-09-13 | Verfahren und Kit für Immunoassay |
Country Status (3)
Country | Link |
---|---|
US (1) | US5434088A (de) |
EP (1) | EP0476545B1 (de) |
DE (1) | DE69125992T2 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6251581B1 (en) | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
PT984282E (pt) * | 1991-05-22 | 2003-12-31 | Dade Behring Marburg Gmbh | Particulas que tem incorporada uma composicao que compreende um composto quimioluminescente |
US5578498A (en) | 1991-05-22 | 1996-11-26 | Behringwerke Ag | Metal chelate containing compositions for use in chemiluminescent assays |
US20010055581A1 (en) | 1994-03-18 | 2001-12-27 | Lawrence Tamarkin | Composition and method for delivery of biologically-active factors |
DE4421907A1 (de) * | 1994-06-24 | 1996-01-04 | Behringwerke Ag | Verfahren zur Durchführung eines Immunoassays in einem Mehrphasensystem |
US5783453A (en) * | 1995-06-29 | 1998-07-21 | Chiron Diagnostics Corporation | Non-separation specific binding chemiluminescent assay |
US6379975B1 (en) | 1996-11-27 | 2002-04-30 | T.A.C. Thrombosis And Coagulation Aktiebolag | Methods and reagents for determining protein S |
US6544797B1 (en) * | 1997-04-09 | 2003-04-08 | Biosite Diagnostics, Inc. | Compositions and methods for inhibiting light-induced inactivation of biological reagents |
CA2285957A1 (en) * | 1997-04-11 | 1998-10-22 | The University Of New Mexico | Modular assembly for reagentless affinity separation and detection of analyte |
US6221612B1 (en) | 1997-08-01 | 2001-04-24 | Aurora Biosciences Corporation | Photon reducing agents for use in fluorescence assays |
US6200762B1 (en) | 1997-08-01 | 2001-03-13 | Aurora Biosciences Corporation | Photon reducing agents and compositions for fluorescence assays |
US6214563B1 (en) | 1997-08-01 | 2001-04-10 | Aurora Biosciences Corporation | Photon reducing agents for reducing undesired light emission in assays |
US7745142B2 (en) | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
WO1999017120A1 (en) * | 1997-09-26 | 1999-04-08 | Becton, Dickinson And Company | Preparing conjugates using polyethylene glycol linkers |
US7229841B2 (en) | 2001-04-30 | 2007-06-12 | Cytimmune Sciences, Inc. | Colloidal metal compositions and methods |
US6407218B1 (en) * | 1997-11-10 | 2002-06-18 | Cytimmune Sciences, Inc. | Method and compositions for enhancing immune response and for the production of in vitro mabs |
WO1999061477A2 (en) * | 1998-05-28 | 1999-12-02 | Bayer Aktiengesellschaft | Monoclonal antibody and assay for detecting piiinp |
IL141383A (en) * | 1999-05-05 | 2005-11-20 | Univ California | Sensor containing a polymer for detecting biological agents and methods utilizing the same |
US6136268A (en) * | 1999-08-17 | 2000-10-24 | Orion Diagnostica | Method for luminescence measurements |
EP1081495B1 (de) * | 1999-09-01 | 2004-03-10 | Invitrogen Corporation | Photon Dämpfer für Fluoreszenzassays |
WO2002001225A2 (en) * | 2000-06-23 | 2002-01-03 | Minerva Biotechnologies Corporation | Tandem signaling assay |
US20020127741A1 (en) * | 2000-12-19 | 2002-09-12 | Miquel Sales Amill | Free Analyte detection system |
US7179658B2 (en) * | 2001-09-06 | 2007-02-20 | Beckman Coulter, Inc. | Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection |
US7939283B2 (en) * | 2001-11-01 | 2011-05-10 | Fisher Scientific Company L.L.C. | Analyte binding turbidity assay |
JP2008504216A (ja) | 2003-12-02 | 2008-02-14 | サイトイミューン サイエンシズ インコーポレイテッド | モノクローナル抗体の生成のための方法および組成物 |
CA2554755A1 (en) * | 2004-01-28 | 2005-08-11 | Cytimmune Sciences, Inc. | Functionalized colloidal metal compositions and methods |
JP4843044B2 (ja) | 2005-10-05 | 2011-12-21 | エフ.ホフマン−ラ ロシュ アーゲー | 非蛍光性エネルギー移動 |
CN100367034C (zh) * | 2005-10-20 | 2008-02-06 | 上海交通大学 | 免疫胶体金粒子荧光淬灭的测量方法 |
US8841134B2 (en) * | 2006-04-10 | 2014-09-23 | Bruker Biospin Corporation | Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications |
US20110014118A1 (en) * | 2007-09-21 | 2011-01-20 | Lawrence Tamarkin | Nanotherapeutic colloidal metal compositions and methods |
US20090104114A1 (en) * | 2007-09-21 | 2009-04-23 | Cytimmune Sciences, Inc. | Nanotherapeutic Colloidal Metal Compositions and Methods |
CA2706700A1 (en) | 2007-11-08 | 2009-05-14 | Cytimmune Sciences, Inc. | Compositions and methods for generating antibodies |
JP5518450B2 (ja) * | 2008-12-04 | 2014-06-11 | 富士フイルム株式会社 | 断片化抗体固定化担体及びその製造方法 |
WO2011057347A1 (en) * | 2009-11-12 | 2011-05-19 | Tgr Biosciences Pty Ltd | Analyte detection |
CN102401829B (zh) * | 2010-09-17 | 2015-04-29 | 上海鑫谱生物科技有限公司 | 一种基于荧光淬灭原理的免疫反应分析方法 |
EP3341508A4 (de) | 2015-08-25 | 2019-05-15 | Bio-Rad Laboratories, Inc. | Digitaler immunoassay |
CN110441514B (zh) * | 2019-06-18 | 2022-11-29 | 北京利德曼生化股份有限公司 | 一种胶乳微球与抗体复合物的制备方法、产品及其应用 |
CN111721931A (zh) * | 2020-06-23 | 2020-09-29 | 广州万孚生物技术股份有限公司 | 一种固相时间分辨荧光免疫标记物及其制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4261968A (en) * | 1979-05-10 | 1981-04-14 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4486530A (en) * | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
IL64574A (en) * | 1981-04-27 | 1986-01-31 | Syva Co | Method for determining the presence of an analyte by determination of the amount of fluorescence in competitive protein binding assays |
US4654300A (en) * | 1982-04-02 | 1987-03-31 | Syntex (U.S.A.) Inc. | Fluorescent microbead quenching assay |
EP0092344A1 (de) * | 1982-04-15 | 1983-10-26 | AMERSHAM INTERNATIONAL plc | Testverfahren |
US4572901A (en) * | 1983-06-23 | 1986-02-25 | Children's Hospital Medical Center Of Northern California | Method and composition for protein immobilization |
US4777128A (en) * | 1986-05-27 | 1988-10-11 | Ethigen Corporation | Fluorescence immunoassay involving energy transfer between two fluorophores |
CA1308022C (en) * | 1988-08-11 | 1992-09-29 | Eleftherios P. Diamandis | Multiple fluorescence labelling with europium chelators |
EP0369545B1 (de) * | 1988-11-15 | 1992-08-19 | H.B.T. Holland Biotechnology B.V. | Verfahren zur Herstellung von Elementarsolen |
-
1991
- 1991-09-13 EP EP91115597A patent/EP0476545B1/de not_active Expired - Lifetime
- 1991-09-13 DE DE69125992T patent/DE69125992T2/de not_active Expired - Fee Related
-
1994
- 1994-05-24 US US08/248,527 patent/US5434088A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0476545A1 (de) | 1992-03-25 |
EP0476545B1 (de) | 1997-05-07 |
DE69125992T2 (de) | 1997-08-21 |
US5434088A (en) | 1995-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |