DE69119819D1 - L-Glutamsäure-Derivate - Google Patents

L-Glutamsäure-Derivate

Info

Publication number
DE69119819D1
DE69119819D1 DE69119819T DE69119819T DE69119819D1 DE 69119819 D1 DE69119819 D1 DE 69119819D1 DE 69119819 T DE69119819 T DE 69119819T DE 69119819 T DE69119819 T DE 69119819T DE 69119819 D1 DE69119819 D1 DE 69119819D1
Authority
DE
Germany
Prior art keywords
glutamic acid
acid derivatives
derivatives
hydroxypyrimidin
diamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69119819T
Other languages
English (en)
Other versions
DE69119819T2 (de
Inventor
Edward C Taylor
Thomas H Schrader
Loren W Walensky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Princeton University filed Critical Princeton University
Publication of DE69119819D1 publication Critical patent/DE69119819D1/de
Application granted granted Critical
Publication of DE69119819T2 publication Critical patent/DE69119819T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69119819T 1990-04-18 1991-03-07 L-Glutamsäure-Derivate Expired - Fee Related DE69119819T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/510,669 US5013738A (en) 1990-04-18 1990-04-18 L-glutamic acid derivatives

Publications (2)

Publication Number Publication Date
DE69119819D1 true DE69119819D1 (de) 1996-07-04
DE69119819T2 DE69119819T2 (de) 1996-11-28

Family

ID=24031685

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69119819T Expired - Fee Related DE69119819T2 (de) 1990-04-18 1991-03-07 L-Glutamsäure-Derivate

Country Status (7)

Country Link
US (1) US5013738A (de)
EP (1) EP0452660B1 (de)
JP (1) JPH05262746A (de)
AT (1) ATE138655T1 (de)
CA (1) CA2037015A1 (de)
DE (1) DE69119819T2 (de)
SG (1) SG49323A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013295A1 (en) * 1992-12-16 1994-06-23 Agouron Pharmaceuticals, Inc. Antiproliferative substituted 5-thiapyrimidinone and 5-selenopyrimidinone compounds
US5945427A (en) * 1995-06-07 1999-08-31 Agouron Pharmaceuticals, Inc. Antiproliferative substituted 5-thiapyrimidinone and 5-selenopyrimidinone compounds
US5594139A (en) * 1993-01-29 1997-01-14 Agouron Pharmaceuticals, Inc. Processes for preparing antiproliferative garft-inhibiting compounds
US5831100A (en) * 1995-06-07 1998-11-03 Agouron Pharmaceuticals, Inc. Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates
ATE353640T1 (de) * 1998-03-27 2007-03-15 Genentech Inc Antagoniste zur behandlung von cd11/cd18 adhäsionsrezeptor-vermittelten krankheiten
JP2005528397A (ja) * 2002-04-05 2005-09-22 ザ スクリプス リサーチ インスティテュート グリシンアミドリボヌクレオチドトランスホルミラーゼの阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
US4871743A (en) * 1988-01-19 1989-10-03 The Trustees Of Princeton University L-glutamic acid derivatives

Also Published As

Publication number Publication date
US5013738A (en) 1991-05-07
DE69119819T2 (de) 1996-11-28
EP0452660A2 (de) 1991-10-23
JPH05262746A (ja) 1993-10-12
SG49323A1 (en) 1998-05-18
ATE138655T1 (de) 1996-06-15
CA2037015A1 (en) 1991-10-19
EP0452660A3 (en) 1992-01-29
EP0452660B1 (de) 1996-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee