ATE138655T1 - L-glutamsäure-derivate - Google Patents

L-glutamsäure-derivate

Info

Publication number
ATE138655T1
ATE138655T1 AT91103482T AT91103482T ATE138655T1 AT E138655 T1 ATE138655 T1 AT E138655T1 AT 91103482 T AT91103482 T AT 91103482T AT 91103482 T AT91103482 T AT 91103482T AT E138655 T1 ATE138655 T1 AT E138655T1
Authority
AT
Austria
Prior art keywords
glutamic acid
acid derivatives
derivatives
hydroxypyrimidin
diamino
Prior art date
Application number
AT91103482T
Other languages
English (en)
Inventor
Edward C Taylor
Thomas H Schrader
Loren W Walensky
Original Assignee
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Princeton filed Critical Univ Princeton
Application granted granted Critical
Publication of ATE138655T1 publication Critical patent/ATE138655T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91103482T 1990-04-18 1991-03-07 L-glutamsäure-derivate ATE138655T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/510,669 US5013738A (en) 1990-04-18 1990-04-18 L-glutamic acid derivatives

Publications (1)

Publication Number Publication Date
ATE138655T1 true ATE138655T1 (de) 1996-06-15

Family

ID=24031685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91103482T ATE138655T1 (de) 1990-04-18 1991-03-07 L-glutamsäure-derivate

Country Status (7)

Country Link
US (1) US5013738A (de)
EP (1) EP0452660B1 (de)
JP (1) JPH05262746A (de)
AT (1) ATE138655T1 (de)
CA (1) CA2037015A1 (de)
DE (1) DE69119819T2 (de)
SG (1) SG49323A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT674516E (pt) * 1992-12-16 2000-05-31 Agouron Pharma Compostos de 5-tiapirimidinona e 5-selenopirimidinona substituidos antiproliferativos
US5945427A (en) * 1995-06-07 1999-08-31 Agouron Pharmaceuticals, Inc. Antiproliferative substituted 5-thiapyrimidinone and 5-selenopyrimidinone compounds
US5594139A (en) * 1993-01-29 1997-01-14 Agouron Pharmaceuticals, Inc. Processes for preparing antiproliferative garft-inhibiting compounds
US5831100A (en) * 1995-06-07 1998-11-03 Agouron Pharmaceuticals, Inc. Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates
JP2002509881A (ja) * 1998-03-27 2002-04-02 ジェネンテク・インコーポレイテッド Ｃｄ１１／ｃｄ１８接着レセプター媒介疾患の治療用アンタゴニスト
CA2481344A1 (en) * 2002-04-05 2003-10-23 The Scripps Research Institute Inhibitors of glycinamide ribonucleotide transformylase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
US4871743A (en) * 1988-01-19 1989-10-03 The Trustees Of Princeton University L-glutamic acid derivatives

Also Published As

Publication number Publication date
SG49323A1 (en) 1998-05-18
US5013738A (en) 1991-05-07
EP0452660A3 (en) 1992-01-29
EP0452660A2 (de) 1991-10-23
DE69119819T2 (de) 1996-11-28
JPH05262746A (ja) 1993-10-12
DE69119819D1 (de) 1996-07-04
EP0452660B1 (de) 1996-05-29
CA2037015A1 (en) 1991-10-19

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties