DE69117029T2 - Verfahren zur herstellung eines durch einbau einer lipophilen wirksubstanz modifizierten lipoproteins - Google Patents

Verfahren zur herstellung eines durch einbau einer lipophilen wirksubstanz modifizierten lipoproteins

Info

Publication number
DE69117029T2
DE69117029T2 DE69117029T DE69117029T DE69117029T2 DE 69117029 T2 DE69117029 T2 DE 69117029T2 DE 69117029 T DE69117029 T DE 69117029T DE 69117029 T DE69117029 T DE 69117029T DE 69117029 T2 DE69117029 T2 DE 69117029T2
Authority
DE
Germany
Prior art keywords
lipoprotein
active substance
pct
modified
installing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69117029T
Other languages
English (en)
Other versions
DE69117029D1 (de
Inventor
Gilles Favre
Patrick Duriez
Francoise Monard
Samadi-Baboli Medhi
Georges Soula
Jean-Charles Fruchart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Lille 2 Droit et Sante
Universite Toulouse III Paul Sabatier
Original Assignee
Universite Lille 2 Droit et Sante
Universite Toulouse III Paul Sabatier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Lille 2 Droit et Sante, Universite Toulouse III Paul Sabatier filed Critical Universite Lille 2 Droit et Sante
Application granted granted Critical
Publication of DE69117029D1 publication Critical patent/DE69117029D1/de
Publication of DE69117029T2 publication Critical patent/DE69117029T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1275—Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
DE69117029T 1990-07-13 1991-07-12 Verfahren zur herstellung eines durch einbau einer lipophilen wirksubstanz modifizierten lipoproteins Expired - Fee Related DE69117029T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9008980A FR2664500B1 (fr) 1990-07-13 1990-07-13 Procede de preparation d'une lipoproteine modifiee par incorporation d'une substance active lipophile, lipoproteine modifiee ainsi obtenue et composition pharmaceutique ou cosmetique la contenant.
PCT/FR1991/000573 WO1992000761A1 (fr) 1990-07-13 1991-07-12 Procede de preparation d'une lipoproteine modifiee par incorporation d'une substance active lipophile

Publications (2)

Publication Number Publication Date
DE69117029D1 DE69117029D1 (de) 1996-03-21
DE69117029T2 true DE69117029T2 (de) 1996-09-19

Family

ID=9398707

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69117029T Expired - Fee Related DE69117029T2 (de) 1990-07-13 1991-07-12 Verfahren zur herstellung eines durch einbau einer lipophilen wirksubstanz modifizierten lipoproteins

Country Status (11)

Country Link
US (1) US5324821A (de)
EP (1) EP0491921B1 (de)
JP (1) JPH0786089B2 (de)
AT (1) ATE133867T1 (de)
AU (1) AU654144B2 (de)
CA (1) CA2066416A1 (de)
DE (1) DE69117029T2 (de)
ES (1) ES2042437T1 (de)
FR (1) FR2664500B1 (de)
GR (1) GR920300128T1 (de)
WO (1) WO1992000761A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869534A (en) * 1992-05-21 1999-02-09 The Picower Institute For Medical Research Glycosylation of lipids and lipid-containing particles, and diagnostic and therapeutic methods and materials derived therefrom
US5842603A (en) * 1990-06-06 1998-12-01 The Coca-Cola Company Postmix juice dispenser
US5615801A (en) * 1990-06-06 1997-04-01 The Coca-Cola Company Juice concentrate package for postmix dispenser
US5874059A (en) * 1992-04-02 1999-02-23 Fundacao E.J. Zerbini Microemulsions labelled with radioactivity used as means for targeting neoplastic cells
AU727447B2 (en) * 1996-07-03 2000-12-14 University Of Pittsburgh Emulsion formulations for hydrophilic active agents
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
US6514523B1 (en) 2000-02-14 2003-02-04 Ottawa Heart Institute Research Corporation Carrier particles for drug delivery and process for preparation
EP1581186A2 (de) * 2002-12-03 2005-10-05 Blanchette Rockefeller Neurosciences Institute Künstliche lipoprotein-träger niederer dichte für den transport von substanzen durch die blut/hirn-schranke
US7803400B2 (en) 2002-12-03 2010-09-28 Blanchette Rockefeller Neurosciences Institute Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier
AU2004212944B2 (en) 2003-02-14 2008-08-21 Children's Hospital & Research Center At Oakland Lipophilic drug delivery vehicle and methods of use thereof
DE10324256B4 (de) * 2003-05-28 2010-04-22 Merz Pharma Gmbh & Co. Kgaa Lipid-Tranferprotein-Systeme und deren kosmetische/dermatologische Anwendung
WO2006073419A2 (en) * 2004-04-01 2006-07-13 Gang Zheng Lipoprotein nanoplatforms
US20100028416A1 (en) * 2008-07-30 2010-02-04 Nitto Denko Corporation Drug carriers
US20160346221A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
LT3328419T (lt) 2015-07-30 2021-11-10 Macrogenics, Inc. Pd-1 surišančios molekulės ir jų panaudojimo būdai
EP3389714A4 (de) 2015-12-14 2019-11-13 MacroGenics, Inc. Bispezifische moleküle mit immunreaktivität mit pd-1 und ctla-4 und verfahren zur verwendung davon

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59163824A (ja) * 1983-03-08 1984-09-14 Hitachi Ltd アライメントスコ−プ
SE456136B (sv) * 1985-06-17 1988-09-12 Oncholab Ab Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
FR2609399A1 (fr) * 1987-01-13 1988-07-15 Ire Celltarg Sa Procede d'incorporation d'un ou plusieurs principes actifs lipophiles dans des lipoproteines, lipoproteines obtenues et composition pharmaceutique les contenant
US5084441A (en) * 1987-03-04 1992-01-28 Shaw Jack M Acetylated low density lipoproteins: a delivery system to phagocytic cells for stimulating immunologic response and host resistance
WO1988009345A1 (en) * 1987-05-20 1988-12-01 The Rogosin Institute Reconstituted hdl particles and uses thereof
DE3815473A1 (de) * 1988-05-06 1989-11-16 Karl Heinz Prof Dr Dr Schmidt Wirkstoff-system fuer den lipidaustausch mit zielstrukturen
US5169933A (en) * 1988-08-15 1992-12-08 Neorx Corporation Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
US5006343A (en) * 1988-12-29 1991-04-09 Benson Bradley J Pulmonary administration of pharmaceutically active substances

Also Published As

Publication number Publication date
FR2664500B1 (fr) 1994-10-28
GR920300128T1 (en) 1993-03-16
AU654144B2 (en) 1994-10-27
ES2042437T1 (es) 1993-12-16
DE69117029D1 (de) 1996-03-21
WO1992000761A1 (fr) 1992-01-23
US5324821A (en) 1994-06-28
JPH06500768A (ja) 1994-01-27
FR2664500A1 (fr) 1992-01-17
JPH0786089B2 (ja) 1995-09-20
AU8215791A (en) 1992-02-04
EP0491921B1 (de) 1996-02-07
CA2066416A1 (fr) 1992-01-14
ATE133867T1 (de) 1996-02-15
EP0491921A1 (de) 1992-07-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee