DE69113840T2 - Verfahren zur Herstellung von 2-Halogeno-3-Hydroxy-3-Phenyl-Propionsäureesterverbindungen. - Google Patents

Verfahren zur Herstellung von 2-Halogeno-3-Hydroxy-3-Phenyl-Propionsäureesterverbindungen.

Info

Publication number
DE69113840T2
DE69113840T2 DE69113840T DE69113840T DE69113840T2 DE 69113840 T2 DE69113840 T2 DE 69113840T2 DE 69113840 T DE69113840 T DE 69113840T DE 69113840 T DE69113840 T DE 69113840T DE 69113840 T2 DE69113840 T2 DE 69113840T2
Authority
DE
Germany
Prior art keywords
halogeno
hydroxy
phenyl
preparation
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69113840T
Other languages
English (en)
Other versions
DE69113840D1 (de
Inventor
Takeji Shibatani
Takuo Nishida
Hiroaki Matsumae
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE69113840D1 publication Critical patent/DE69113840D1/de
Publication of DE69113840T2 publication Critical patent/DE69113840T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
DE69113840T 1990-03-22 1991-03-13 Verfahren zur Herstellung von 2-Halogeno-3-Hydroxy-3-Phenyl-Propionsäureesterverbindungen. Expired - Fee Related DE69113840T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2069570A JPH0779706B2 (ja) 1990-03-22 1990-03-22 ２―クロロ―３―ヒドロキシ―３―フエニルプロピオン酸エステル類の製法

Publications (2)

Publication Number Publication Date
DE69113840D1 DE69113840D1 (de) 1995-11-23
DE69113840T2 true DE69113840T2 (de) 1996-03-21

Family

ID=13406577

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69113840T Expired - Fee Related DE69113840T2 (de) 1990-03-22 1991-03-13 Verfahren zur Herstellung von 2-Halogeno-3-Hydroxy-3-Phenyl-Propionsäureesterverbindungen.

Country Status (9)

Country Link
US (1) US5204248A (de)
EP (1) EP0447938B1 (de)
JP (1) JPH0779706B2 (de)
KR (1) KR0135415B1 (de)
AU (1) AU646436B2 (de)
CA (1) CA2038011C (de)
DE (1) DE69113840T2 (de)
ES (1) ES2078370T3 (de)
HK (1) HK1000800A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1249777B (it) * 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
JP3087419B2 (ja) * 1991-11-14 2000-09-11 味の素株式会社 （ｓ）−１−フェニル−１，３−プロパンジオールまたはその誘導体の製造方法
WO1994013828A1 (en) * 1992-12-10 1994-06-23 Chiroscience Limited Chiral arylpropionates and their use
DK0862645T3 (da) * 1995-09-27 2003-04-07 Schering Corp Stereoselektiv mikrobiel reduktionsproces
DE10244811A1 (de) 2002-09-26 2004-04-08 Bayer Ag Verfahren zur Herstellung von 3-Heteroaryl-3-hydroxy-propansäurederivaten
US7501427B2 (en) * 2003-08-14 2009-03-10 Array Biopharma, Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058087A (ja) * 1983-09-09 1985-04-04 Daikin Ind Ltd α−フルオロ−β−ヒドロキシカルボン酸エステル類の製造方法
DE3332562A1 (de) * 1983-09-09 1985-03-28 Basf Ag, 6700 Ludwigshafen 2-oxocarbonsaeurereduktase, ihre herstellung und verwendung
EP0144832A3 (de) * 1983-12-06 1987-01-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung optisch aktiver, alpha-substituierter 3-Hydroxypropionsäurederivate
GB8406318D0 (en) * 1984-03-10 1984-04-11 Tanabe Seiyaku Co 1 5-benzothiazepine derivatives
JPS6330000A (ja) * 1986-07-23 1988-02-08 松下電器産業株式会社 回路基板最適抵抗実装方法
JPH07118371B2 (ja) * 1987-06-29 1995-12-18 松下電器産業株式会社 面状発熱体
WO1989007648A1 (en) * 1988-02-12 1989-08-24 Daicel Chemical Industries, Ltd. Process for preparing optically active 2-hydroxy acid derivatives
JPH01226881A (ja) * 1988-03-04 1989-09-11 Tanabe Seiyaku Co Ltd 光学活性３−フェニルグリシッド酸エステル類化合物の製法
NL8801311A (nl) * 1988-05-20 1989-12-18 Stamicarbon Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
FI95931C (fi) * 1988-09-02 1996-04-10 Tanabe Seiyaku Co Menetelmä (2R,3S)-3-(4-metoksifenyyli)glysidiinihapon alemman alkyyliesterin valmistamiseksi
FR2649980A1 (de) * 1989-07-18 1991-01-25 Sanofi Sa

Also Published As

Publication number Publication date
ES2078370T3 (es) 1995-12-16
AU646436B2 (en) 1994-02-24
DE69113840D1 (de) 1995-11-23
EP0447938B1 (de) 1995-10-18
CA2038011C (en) 1999-05-25
KR0135415B1 (ko) 1998-04-23
JPH0779706B2 (ja) 1995-08-30
CA2038011A1 (en) 1991-09-23
US5204248A (en) 1993-04-20
EP0447938A1 (de) 1991-09-25
JPH03272691A (ja) 1991-12-04
KR910016932A (ko) 1991-11-05
HK1000800A1 (en) 1998-05-01
AU7288791A (en) 1991-10-03

Similar Documents

Publication Publication Date Title
DE69201978T2 (de) Verfahren zur Herstellung von Terephthalsäure.
DE69113695D1 (de) Verfahren zur Herstellung von Perfluoralkoxysulfonverbindungen.
DE69123662D1 (de) Verfahren zur Herstellung von y-Methacryloxypropylsilanverbindungen
DE69005542D1 (de) Verfahren zur Herstellung von 3-Pentensäure.
DE59400025D1 (de) Verfahren zur Herstellung von 2-Alkyl-4-fluormethyl-thiazolcarbonsäure-alkylestern.
DE59404418D1 (de) Verfahren zur Herstellung von aliphatischen Omega-Difluorcarboxylverbindungen
DE69113840D1 (de) Verfahren zur Herstellung von 2-Halogeno-3-Hydroxy-3-Phenyl-Propionsäureesterverbindungen.
DE59106900D1 (de) Verfahren zur Herstellung von substituierten 3-Aminoacrylestern.
DE59204060D1 (de) Verfahren zur Herstellung von 1-Fluor-cyclopropan-1-carbonsäure.
DE69103913T2 (de) Verfahren zur Herstellung von Dodekandicarbonsäure.
DE59209261D1 (de) Verfahren zur Herstellung von substituierten 3-Alkoxy-acrylestern
DE59006113D1 (de) Verfahren zur Herstellung von Tetronsäurealkylestern.
DE69219019T2 (de) Verfahren zur Herstellung von ortho-Alkoxybenzoesäure
DE69304634D1 (de) Verfahren zur Herstellung von N,O-Dialkylhydroxycarbaminsäureestern
DE59200677D1 (de) Verfahren zur Herstellung von Alkansulfonylbenzoesäuren.
DE59104571D1 (de) Verfahren zur Herstellung von Vinylphosphonsäurederivaten.
DE69226393D1 (de) Verfahren zur Herstellung von 2-Fluorisobuttersäureester
DE69107740T2 (de) Verfahren zur Herstellung von (Cyanofluormethyl)-Phosphonsäureestern.
DE69103647D1 (de) Verfahren zur Herstellung von Naphthalindicarbonsäure.
DE59303528D1 (de) Verfahren zur Herstellung von Beta-aminoacrylsäureestern
DE59205852D1 (de) Verfahren zur Herstellung von Oxadimethacrylsäure
DE59007620D1 (de) Verfahren zur Herstellung von 3-Methylchinolin-8-carbonsäure.
DE69025750T2 (de) Verfahren zur Herstellung von alpha-Hydroxyisobutyrsäure
DE59209536D1 (de) Verfahren zur Herstellung von Tetrahydropyrancarbonsäureestern
DE58907865D1 (de) Verfahren zur Herstellung von alpha-Ketocarbonsäureestern.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee