DE69113379D1 - 3-Aryl-4(3H)chinazolinone als CCK Antagonisten und diese enthaltende pharmazeutische Zusammensetzungen. - Google Patents

3-Aryl-4(3H)chinazolinone als CCK Antagonisten und diese enthaltende pharmazeutische Zusammensetzungen.

Info

Publication number
DE69113379D1
DE69113379D1 DE69113379T DE69113379T DE69113379D1 DE 69113379 D1 DE69113379 D1 DE 69113379D1 DE 69113379 T DE69113379 T DE 69113379T DE 69113379 T DE69113379 T DE 69113379T DE 69113379 D1 DE69113379 D1 DE 69113379D1
Authority
DE
Germany
Prior art keywords
quinazolinones
aryl
pharmaceutical compositions
compositions containing
cck antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69113379T
Other languages
English (en)
Other versions
DE69113379T2 (de
Inventor
Jefferson Ray Mccowan
Kenneth Jeff Thrasher
Melvin Joseph Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69113379D1 publication Critical patent/DE69113379D1/de
Publication of DE69113379T2 publication Critical patent/DE69113379T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69113379T 1990-09-13 1991-09-12 3-Aryl-4(3H)chinazolinone als CCK Antagonisten und diese enthaltende pharmazeutische Zusammensetzungen. Expired - Fee Related DE69113379T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/581,943 US5075313A (en) 1990-09-13 1990-09-13 3-aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof

Publications (2)

Publication Number Publication Date
DE69113379D1 true DE69113379D1 (de) 1995-11-02
DE69113379T2 DE69113379T2 (de) 1996-03-21

Family

ID=24327210

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69113379T Expired - Fee Related DE69113379T2 (de) 1990-09-13 1991-09-12 3-Aryl-4(3H)chinazolinone als CCK Antagonisten und diese enthaltende pharmazeutische Zusammensetzungen.

Country Status (20)

Country Link
US (1) US5075313A (de)
EP (1) EP0475755B1 (de)
JP (1) JPH04247080A (de)
KR (1) KR920006350A (de)
CN (1) CN1059722A (de)
AU (1) AU641043B2 (de)
CA (1) CA2050994A1 (de)
CZ (1) CZ279774B6 (de)
DE (1) DE69113379T2 (de)
ES (1) ES2078455T3 (de)
FI (1) FI914262A (de)
HU (1) HUT59128A (de)
IE (1) IE913217A1 (de)
IL (1) IL99402A0 (de)
MX (1) MX9101035A (de)
NO (1) NO913579L (de)
NZ (1) NZ239712A (de)
PT (1) PT98915A (de)
YU (1) YU151691A (de)
ZA (1) ZA917149B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340801A (en) * 1991-05-08 1994-08-23 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cholecystokinin and gastrin antagonistic properties
US5204354A (en) * 1992-02-14 1993-04-20 Merck & Co., Inc. Substituted quinazolinones as neurotensin antagonists useful in the treatment of CNS disorders
GB0031315D0 (en) * 2000-12-21 2001-02-07 Glaxo Group Ltd Indole derivatives
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
US7235543B2 (en) 2003-03-07 2007-06-26 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US7348338B2 (en) * 2003-07-17 2008-03-25 Plexxikon, Inc. PPAR active compounds
RU2356889C2 (ru) 2003-07-17 2009-05-27 Плекссикон, Инк. Соединения, являющиеся активными по отношению к рецепторам, активируемым пролифератором пероксисом
GB0319126D0 (en) * 2003-08-14 2003-09-17 Smithkline Beecham Corp Chemical compounds
CA2588953A1 (en) * 2004-11-30 2006-06-08 Plexxikon, Inc. Ppar active compounds
JP2008521831A (ja) * 2004-11-30 2008-06-26 プレキシコン，インコーポレーテッド Ｐｐａｒ活性化合物
AU2006287528A1 (en) * 2005-09-07 2007-03-15 Plexxikon, Inc. 1 , 4 and 1 , 5-disubstituted indole derivatives for use as PPAR active compounds
WO2007030567A2 (en) * 2005-09-07 2007-03-15 Plexxikon, Inc. Pparactive compounds
WO2007056124A2 (en) * 2005-11-04 2007-05-18 Hydra Biosciences, Inc. Compounds for modulating trpv3 function
PE20090159A1 (es) * 2007-03-08 2009-02-21 Plexxikon Inc COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
JP2023512664A (ja) 2020-01-29 2023-03-28 カマリ ファーマ リミテッド 皮膚障害の治療に使用するための化合物及び組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ192392A (en) * 1978-12-19 1983-02-15 M Ishikawa 3-(substituted (phenyl or pyridyl)) -3,4-dihydroquinazolin-4-ones
EP0336356A3 (de) * 1988-04-05 1991-09-25 Abbott Laboratories Tryptophan-Derivate, verwendbar als CCK-Gegner

Also Published As

Publication number Publication date
KR920006350A (ko) 1992-04-27
AU641043B2 (en) 1993-09-09
AU8382991A (en) 1992-03-19
CN1059722A (zh) 1992-03-25
HUT59128A (en) 1992-04-28
JPH04247080A (ja) 1992-09-03
CA2050994A1 (en) 1992-03-14
CS279991A3 (en) 1992-04-15
EP0475755B1 (de) 1995-09-27
FI914262A (fi) 1992-03-14
CZ279774B6 (cs) 1995-06-14
DE69113379T2 (de) 1996-03-21
EP0475755A1 (de) 1992-03-18
PT98915A (pt) 1992-08-31
NZ239712A (en) 1993-06-25
IL99402A0 (en) 1992-08-18
HU912921D0 (en) 1992-01-28
US5075313A (en) 1991-12-24
IE913217A1 (en) 1992-02-25
MX9101035A (es) 1992-05-04
NO913579L (no) 1992-03-16
YU151691A (sh) 1994-01-20
ZA917149B (en) 1992-05-27
FI914262A0 (fi) 1991-09-10
ES2078455T3 (es) 1995-12-16
NO913579D0 (no) 1991-09-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee