DE69111801D1 - Vakzin gegen hepatitis b. - Google Patents
Vakzin gegen hepatitis b.Info
- Publication number
- DE69111801D1 DE69111801D1 DE69111801T DE69111801T DE69111801D1 DE 69111801 D1 DE69111801 D1 DE 69111801D1 DE 69111801 T DE69111801 T DE 69111801T DE 69111801 T DE69111801 T DE 69111801T DE 69111801 D1 DE69111801 D1 DE 69111801D1
- Authority
- DE
- Germany
- Prior art keywords
- vhbsag
- vaccine against
- against hepatitis
- fragment
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 241000700721 Hepatitis B virus Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909007024A GB9007024D0 (en) | 1990-03-29 | 1990-03-29 | Novel vaccine |
PCT/GB1991/000444 WO1991014703A1 (en) | 1990-03-29 | 1991-03-25 | Hepatitis b vaccine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69111801D1 true DE69111801D1 (de) | 1995-09-07 |
DE69111801T2 DE69111801T2 (de) | 1995-12-14 |
Family
ID=10673467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69111801T Expired - Fee Related DE69111801T2 (de) | 1990-03-29 | 1991-03-25 | Vakzin gegen hepatitis b. |
Country Status (16)
Country | Link |
---|---|
US (1) | US6099840A (de) |
EP (1) | EP0522030B1 (de) |
JP (2) | JP2876091B2 (de) |
KR (1) | KR100208129B1 (de) |
AT (1) | ATE125821T1 (de) |
CA (1) | CA2078694C (de) |
DE (1) | DE69111801T2 (de) |
DK (1) | DK0522030T3 (de) |
ES (1) | ES2075440T3 (de) |
GB (1) | GB9007024D0 (de) |
GR (1) | GR3017804T3 (de) |
IE (1) | IE67877B1 (de) |
NZ (1) | NZ237611A (de) |
PT (1) | PT97159B (de) |
WO (1) | WO1991014703A1 (de) |
ZA (1) | ZA912305B (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5565354A (en) * | 1986-09-05 | 1996-10-15 | Sandoz Ltd. | Production of human monoclonal antibodies specific for hepatitis B surface antigen |
CA2067003A1 (en) * | 1991-04-29 | 1992-10-30 | Peter J. Kniskern | Hbsag escape mutant vaccine |
EP0533263A3 (en) * | 1991-09-20 | 1994-06-08 | Merck & Co Inc | A multivalent hepatitis b virus vaccine |
AU3269793A (en) * | 1991-12-27 | 1993-07-28 | Gensci Limited | Method for obtaining recombinant surface antigen of hepatitis B, antigen and vaccine based on it |
CA2118026A1 (en) * | 1992-04-14 | 1993-10-28 | Guy T. Layton | Induction of ctl responses |
ES2118963T3 (es) | 1992-05-23 | 1998-10-01 | Smithkline Beecham Biolog | Vacunas combinadas, que contienen antigeno de superficie de la hepatitis b y otros antigenos. |
US5750106A (en) * | 1993-01-28 | 1998-05-12 | Novartis Ag | Human monoclonal antibodies to cytomegalovirus |
US6030616A (en) * | 1993-03-24 | 2000-02-29 | Imperial College Of Science, Technology & Medicine | Hepatitis B escape mutant specific binding molecules |
PL310699A1 (en) * | 1993-03-24 | 1995-12-27 | Imperial College | Molecule specifically bonding itself with antigen determinant of escape mutation of hepatitis b |
US5595739A (en) * | 1993-05-07 | 1997-01-21 | Abbott Laboratories | Hepatitis B virus mutants, reagents and methods for detection |
GB9401987D0 (en) * | 1994-02-02 | 1994-03-30 | Imperial College | Modified nucleic acid |
GB9623233D0 (en) | 1996-11-07 | 1997-01-08 | Smithkline Beecham Biolog | Vaccine composition |
EP0919568A1 (de) | 1997-12-01 | 1999-06-02 | Sorin Diagnostics S.r.l. | Fluchtmutanten des Oberflächenantigens des Hepatitis B Virus |
MXPA00012724A (es) * | 1998-06-19 | 2003-02-10 | Government Of The Republic Of | Una cepa viral de hepatitis b inducida por vacuna y usos de la misma. |
CN101926993B (zh) | 1998-10-16 | 2013-12-04 | 史密丝克莱恩比彻姆生物有限公司 | 佐剂系统及疫苗 |
AUPP967999A0 (en) | 1999-04-09 | 1999-05-06 | North Western Health Care Network | Viral variants |
UA79735C2 (uk) | 2000-08-10 | 2007-07-25 | Глаксосмітклайн Байолоджікалз С.А. | Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах |
FR2815634B1 (fr) * | 2000-10-20 | 2003-10-31 | Biomerieux Sa | Anticorps monoclonaux diriges contre des virus de l'hepatite b |
JP4430677B2 (ja) * | 2004-09-22 | 2010-03-10 | 株式会社先端生命科学研究所 | B型肝炎ウイルスs抗原の検出法 |
US8119146B2 (en) * | 2005-04-18 | 2012-02-21 | Angelica Medina-Selby | Expressing hepatitis B virus surface antigen for vaccine preparation |
EP2207035B1 (de) | 2006-03-14 | 2013-10-16 | Oregon Health and Science University | Methoden zur Detektion einer Mycobakterium tuberculosis Infektion |
PL2097102T3 (pl) | 2006-09-07 | 2012-10-31 | Glaxosmithkline Biologicals Sa | Szczepionka skojarzona o zmniejszonej ilości antygenu wirusa polio |
CA2678404C (en) | 2007-02-28 | 2019-03-19 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
US20100074918A1 (en) | 2007-05-02 | 2010-03-25 | Jan Poolman | Vaccine |
EP2293813A4 (de) | 2008-05-23 | 2012-07-11 | Univ Michigan | Nanoemulsionsvakzine |
WO2010099472A2 (en) | 2009-02-27 | 2010-09-02 | The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services | Spanx-b polypeptides and their use |
GB201105981D0 (en) | 2011-04-08 | 2011-05-18 | Glaxosmithkline Biolog Sa | Novel process |
EP2858674B1 (de) * | 2012-07-10 | 2019-01-30 | Green Cross Corporation | Antikörperzusammensetzung zur prävention oder behandlung von mutanten hepatitis-b-virusinfektionen |
WO2014043518A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury protein, non-poxvirus non-yeast vectors encoding brachyury protein, and their use |
RU2603729C2 (ru) * | 2015-04-24 | 2016-11-27 | Закрытое акционерное общество научно-производственная компания "Комбиотех" | Рекомбинантная вакцина для профилактики вирусного гепатита в (варианты) |
RU2586513C1 (ru) * | 2015-04-24 | 2016-06-10 | Закрытое акционерное общество научно-производственная компания "Комбиотех" | РЕКОМБИНАНТНЫЙ ШТАММ ДРОЖЖЕЙ Hansenula polymorpha - ПРОДУЦЕНТ МУТАНТНОГО ПОВЕРХНОСТНОГО АНТИГЕНА ВИРУСА ГЕПАТИТА В (ВАРИАНТЫ) |
WO2017024000A1 (en) | 2015-08-03 | 2017-02-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use |
-
1990
- 1990-03-29 GB GB909007024A patent/GB9007024D0/en active Pending
-
1991
- 1991-03-25 EP EP91907263A patent/EP0522030B1/de not_active Expired - Lifetime
- 1991-03-25 JP JP3506486A patent/JP2876091B2/ja not_active Expired - Fee Related
- 1991-03-25 DK DK91907263.7T patent/DK0522030T3/da active
- 1991-03-25 WO PCT/GB1991/000444 patent/WO1991014703A1/en active IP Right Grant
- 1991-03-25 AT AT91907263T patent/ATE125821T1/de not_active IP Right Cessation
- 1991-03-25 ES ES91907263T patent/ES2075440T3/es not_active Expired - Lifetime
- 1991-03-25 DE DE69111801T patent/DE69111801T2/de not_active Expired - Fee Related
- 1991-03-25 CA CA002078694A patent/CA2078694C/en not_active Expired - Fee Related
- 1991-03-25 KR KR1019920702341A patent/KR100208129B1/ko not_active IP Right Cessation
- 1991-03-27 IE IE102291A patent/IE67877B1/en not_active IP Right Cessation
- 1991-03-27 PT PT97159A patent/PT97159B/pt not_active IP Right Cessation
- 1991-03-27 NZ NZ237611A patent/NZ237611A/xx unknown
- 1991-03-27 ZA ZA912305A patent/ZA912305B/xx unknown
-
1995
- 1995-06-07 US US08/479,609 patent/US6099840A/en not_active Expired - Fee Related
- 1995-10-18 GR GR950402907T patent/GR3017804T3/el unknown
-
1998
- 1998-09-24 JP JP10269188A patent/JP3049018B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2078694A1 (en) | 1991-09-30 |
JPH11178591A (ja) | 1999-07-06 |
WO1991014703A1 (en) | 1991-10-03 |
ES2075440T3 (es) | 1995-10-01 |
JP2876091B2 (ja) | 1999-03-31 |
ZA912305B (en) | 1992-01-29 |
DK0522030T3 (da) | 1995-12-27 |
ATE125821T1 (de) | 1995-08-15 |
IE67877B1 (en) | 1996-05-01 |
JP3049018B2 (ja) | 2000-06-05 |
EP0522030B1 (de) | 1995-08-02 |
CA2078694C (en) | 1998-10-27 |
US6099840A (en) | 2000-08-08 |
PT97159B (pt) | 1998-07-31 |
EP0522030A1 (de) | 1993-01-13 |
AU7561391A (en) | 1991-10-21 |
NZ237611A (en) | 1994-09-27 |
PT97159A (pt) | 1991-12-31 |
GB9007024D0 (en) | 1990-05-30 |
IE911022A1 (en) | 1991-10-09 |
AU642729B2 (en) | 1993-10-28 |
DE69111801T2 (de) | 1995-12-14 |
GR3017804T3 (en) | 1996-01-31 |
JPH05505805A (ja) | 1993-08-26 |
KR100208129B1 (ko) | 1999-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: GROSSE, BOCKHORNI, SCHUMACHER, 81476 MUENCHEN |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: GROSSE, SCHUMACHER, KNAUER, VON HIRSCHHAUSEN, 8033 |
|
8339 | Ceased/non-payment of the annual fee |