DE69104048T2 - Beseitigung interner initiation des löslichen cd4-gens. - Google Patents

Beseitigung interner initiation des löslichen cd4-gens.

Info

Publication number
DE69104048T2
DE69104048T2 DE69104048T DE69104048T DE69104048T2 DE 69104048 T2 DE69104048 T2 DE 69104048T2 DE 69104048 T DE69104048 T DE 69104048T DE 69104048 T DE69104048 T DE 69104048T DE 69104048 T2 DE69104048 T2 DE 69104048T2
Authority
DE
Germany
Prior art keywords
gene
soluble
removal
internal initiation
initiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69104048T
Other languages
English (en)
Other versions
DE69104048D1 (de
Inventor
Richard Kirschner
John Mott
Frances Eckenrode
David Brunner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DE69104048D1 publication Critical patent/DE69104048D1/de
Publication of DE69104048T2 publication Critical patent/DE69104048T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69104048T 1990-08-06 1991-07-02 Beseitigung interner initiation des löslichen cd4-gens. Expired - Fee Related DE69104048T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56286190A 1990-08-06 1990-08-06
PCT/US1991/004565 WO1992002626A1 (en) 1990-08-06 1991-07-02 Eliminating internal initiation of soluble cd4 gene

Publications (2)

Publication Number Publication Date
DE69104048D1 DE69104048D1 (de) 1994-10-20
DE69104048T2 true DE69104048T2 (de) 1995-02-09

Family

ID=24248102

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69104048T Expired - Fee Related DE69104048T2 (de) 1990-08-06 1991-07-02 Beseitigung interner initiation des löslichen cd4-gens.

Country Status (9)

Country Link
US (2) US5759852A (de)
EP (1) EP0542761B1 (de)
JP (1) JPH06503468A (de)
AT (1) ATE111526T1 (de)
AU (1) AU8101791A (de)
DE (1) DE69104048T2 (de)
DK (1) DK0542761T3 (de)
ES (1) ES2060398T3 (de)
WO (1) WO1992002626A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395549B1 (en) 1998-10-22 2002-05-28 Medical College Of Georgia Research Institute, Inc. Long terminal repeat, enhancer, and insulator sequences for use in recombinant vectors
CA2571781C (en) * 2004-06-28 2015-05-12 Yeda Research And Development Co. Ltd Chimeric proteins and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874702A (en) * 1980-09-08 1989-10-17 Biogen, Inc. Vectors and methods for making such vectors and for expressive cloned genes
US5182196A (en) * 1985-10-09 1993-01-26 Biogen, Inc. Expression systems for overproduction of desired proteins
DE3874885T2 (de) * 1987-10-16 1993-03-18 Sakamaki Mfg Spannvorrichtung fuer werkzeuge.
US5206353A (en) * 1988-07-23 1993-04-27 The United States Of America As Represented By The Department Of Health And Human Services CD-4/cytotoxic gene fusions
IL91070A (en) * 1988-07-23 1995-03-30 Us Commerce Cytotoxic agents against certain viral infections
WO1990001367A1 (en) * 1988-08-08 1990-02-22 Thermolytica Corporation Thermolytic detoxification reactor system

Also Published As

Publication number Publication date
DK0542761T3 (da) 1995-03-20
EP0542761A1 (de) 1993-05-26
US5759852A (en) 1998-06-02
AU8101791A (en) 1992-03-02
JPH06503468A (ja) 1994-04-21
US5510256A (en) 1996-04-23
DE69104048D1 (de) 1994-10-20
ATE111526T1 (de) 1994-09-15
EP0542761B1 (de) 1994-09-14
ES2060398T3 (es) 1994-11-16
WO1992002626A1 (en) 1992-02-20

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee