DE69033459D1 - Prostaglandin-I-Analoga - Google Patents

Prostaglandin-I-Analoga

Info

Publication number
DE69033459D1
DE69033459D1 DE69033459T DE69033459T DE69033459D1 DE 69033459 D1 DE69033459 D1 DE 69033459D1 DE 69033459 T DE69033459 T DE 69033459T DE 69033459 T DE69033459 T DE 69033459T DE 69033459 D1 DE69033459 D1 DE 69033459D1
Authority
DE
Germany
Prior art keywords
group
prostaglandin
analogs
alkyl group
prostagrandine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69033459T
Other languages
English (en)
Other versions
DE69033459T2 (de
Inventor
Ryuzo Ueno
Ryuji Ueno
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Publication of DE69033459D1 publication Critical patent/DE69033459D1/de
Application granted granted Critical
Publication of DE69033459T2 publication Critical patent/DE69033459T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69033459T 1988-09-16 1990-05-10 Prostaglandin-I-Analoga Expired - Fee Related DE69033459T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8821817A GB2225573A (en) 1988-09-16 1988-09-16 13,14-dihydro-15-keto-PGFs
JP63286274A JPH0791218B2 (ja) 1988-09-16 1988-11-10 新規プロスタグランジンｉ類

Publications (2)

Publication Number Publication Date
DE69033459D1 true DE69033459D1 (de) 2000-03-23
DE69033459T2 DE69033459T2 (de) 2000-06-15

Family

ID=40130684

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69033459T Expired - Fee Related DE69033459T2 (de) 1988-09-16 1990-05-10 Prostaglandin-I-Analoga

Country Status (9)

Country Link
EP (1) EP0455899B1 (de)
JP (1) JPH0791218B2 (de)
KR (1) KR950005777B1 (de)
AT (1) ATE189813T1 (de)
DE (1) DE69033459T2 (de)
DK (1) DK0455899T3 (de)
ES (1) ES2143974T3 (de)
GB (1) GB2225573A (de)
GR (1) GR3033353T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5107014A (en) * 1990-05-10 1992-04-21 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandin I analogue

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3505386A (en) * 1965-12-29 1970-04-07 Upjohn Co Compounds related to prostaglandins
US3435053A (en) * 1966-06-06 1969-03-25 Upjohn Co Cyclopenta(b)pyrans
US4053467A (en) * 1974-07-03 1977-10-11 American Home Products Corporation Prostaglandin derivatives
DE2517771A1 (de) * 1975-04-18 1976-10-28 Schering Ag Neue prostaglandin-acetylen-analoga und verfahren zu ihrer herstellung
US4089885A (en) * 1976-11-05 1978-05-16 American Home Products Corporation Prostaglandin derivatives
GB2013661B (en) * 1978-01-26 1982-11-10 Erba Farmitalia 9-deoxy-9 -methylene isosteres of pgi2
IT1113341B (it) * 1978-03-31 1986-01-20 Ono Pharmaceutical Co Analoghi della 6,9-metano-pgi2
EP0134153B1 (de) * 1983-08-19 1989-04-19 Sagami Chemical Research Center Derivate des Bicyclo[3.3.0]oktans und ihre Herstellung

Also Published As

Publication number Publication date
ATE189813T1 (de) 2000-03-15
GB2225573A (en) 1990-06-06
KR950005777B1 (ko) 1995-05-30
GR3033353T3 (en) 2000-09-29
KR910019969A (ko) 1991-12-19
ES2143974T3 (es) 2000-06-01
DE69033459T2 (de) 2000-06-15
GB8821817D0 (en) 1988-10-19
DK0455899T3 (da) 2000-06-05
JPH0791218B2 (ja) 1995-10-04
JPH02131446A (ja) 1990-05-21
EP0455899B1 (de) 2000-02-16
EP0455899A1 (de) 1991-11-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SUCAMPO AG, ZUG, CH

8339 Ceased/non-payment of the annual fee