DE69022707T2 - Methode zur Fluordecarboxylierung. - Google Patents

Methode zur Fluordecarboxylierung.

Info

Publication number
DE69022707T2
DE69022707T2 DE69022707T DE69022707T DE69022707T2 DE 69022707 T2 DE69022707 T2 DE 69022707T2 DE 69022707 T DE69022707 T DE 69022707T DE 69022707 T DE69022707 T DE 69022707T DE 69022707 T2 DE69022707 T2 DE 69022707T2
Authority
DE
Germany
Prior art keywords
fluorodecarboxylation
fluorodecarboxylation method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69022707T
Other languages
English (en)
Other versions
DE69022707D1 (de
Inventor
Donald F Halpern
Mark L Robin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Ohmeda Pharmaceutical Products Division Inc Liberty Corner Nj Us
OHMEDA PHARMA PROD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohmeda Pharmaceutical Products Division Inc Liberty Corner Nj Us, OHMEDA PHARMA PROD filed Critical Ohmeda Pharmaceutical Products Division Inc Liberty Corner Nj Us
Publication of DE69022707D1 publication Critical patent/DE69022707D1/de
Application granted granted Critical
Publication of DE69022707T2 publication Critical patent/DE69022707T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • C07C43/123—Saturated ethers containing halogen both carbon chains are substituted by halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69022707T 1990-01-16 1990-10-30 Methode zur Fluordecarboxylierung. Expired - Lifetime DE69022707T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/464,834 US4996371A (en) 1990-01-16 1990-01-16 Method for fluorodecarboxylation

Publications (2)

Publication Number Publication Date
DE69022707D1 DE69022707D1 (de) 1995-11-02
DE69022707T2 true DE69022707T2 (de) 1996-04-04

Family

ID=23845428

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022707T Expired - Lifetime DE69022707T2 (de) 1990-01-16 1990-10-30 Methode zur Fluordecarboxylierung.

Country Status (5)

Country Link
US (2) US4996371A (de)
EP (1) EP0437689B1 (de)
JP (1) JPH0637400B2 (de)
CA (1) CA2027522C (de)
DE (1) DE69022707T2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637776A (en) * 1992-12-10 1997-06-10 Imperial Chemical Industries Plc Production of hydrofluorocarbons
US5492111A (en) * 1993-01-28 1996-02-20 University Of Iowa Research Foundation Method of elimination of volatile degradation products of sevoflurane during anesthesia
US5391579A (en) * 1993-01-28 1995-02-21 University Of Iowa Research Foundation Deuterated sevoflurane as an inhalational anesthetic
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US6303831B1 (en) 2000-06-01 2001-10-16 Abbott Laboratories Synthetic method for fluoromethylation of halogenated alcohols
US6271422B1 (en) 2000-06-01 2001-08-07 Abbott Laboratories Method for fluoromethylation of alcohols via halogenative decarboxylation
US6245949B1 (en) 2000-06-01 2001-06-12 Abbott Laboratories Synthetic method for the fluoromethylation of alcohols
US7138551B2 (en) * 2004-11-05 2006-11-21 E. I. Du Pont De Nemours And Company Purification of fluorinated alcohols
US20060258755A1 (en) * 2005-04-18 2006-11-16 Terrell Ross C Preparation of sevoflurane with negligible water content
JP5114880B2 (ja) * 2006-07-06 2013-01-09 ダイキン工業株式会社 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法
JP5163064B2 (ja) * 2007-11-13 2013-03-13 ダイキン工業株式会社 新規カルボン酸エステル、その用途及びその製造方法
PT105138B (pt) * 2010-06-01 2012-11-06 Hovione Farmaciencia S A Método para a preparação de compostos orgânicos monofluorometilados biologicamente activos
PT105723B (pt) 2011-05-26 2014-03-24 Hovione Farmaci Ncia S A Método para a preparação de compostos orgânicos biologicamente activos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US4250334A (en) * 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4847427A (en) * 1988-04-13 1989-07-11 E. I. Du Pont De Nemours And Company Process for preparing fluorocarbon polyethers
US4874901A (en) * 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
US4874902A (en) * 1988-05-20 1989-10-17 Boc, Inc. Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether

Also Published As

Publication number Publication date
JPH03220132A (ja) 1991-09-27
DE69022707D1 (de) 1995-11-02
USRE35568E (en) 1997-07-22
JPH0637400B2 (ja) 1994-05-18
CA2027522C (en) 1997-09-30
EP0437689A1 (de) 1991-07-24
US4996371A (en) 1991-02-26
EP0437689B1 (de) 1995-09-27
CA2027522A1 (en) 1991-07-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BAXTER INTERNATIONAL INC. (N.D.GES.D. STAATES DELA