DE69021470T2 - Transfervorrichtung für flüssigkeiten. - Google Patents

Transfervorrichtung für flüssigkeiten.

Info

Publication number
DE69021470T2
DE69021470T2 DE69021470T DE69021470T DE69021470T2 DE 69021470 T2 DE69021470 T2 DE 69021470T2 DE 69021470 T DE69021470 T DE 69021470T DE 69021470 T DE69021470 T DE 69021470T DE 69021470 T2 DE69021470 T2 DE 69021470T2
Authority
DE
Germany
Prior art keywords
liquid
channel
site
reagent
channels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69021470T
Other languages
English (en)
Other versions
DE69021470D1 (de
Inventor
Roger Bunce
Gary Thorpe
John Gibbons
Louise Bevan
Matthew Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898906833A external-priority patent/GB8906833D0/en
Priority claimed from GB898922513A external-priority patent/GB8922513D0/en
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Application granted granted Critical
Publication of DE69021470D1 publication Critical patent/DE69021470D1/de
Publication of DE69021470T2 publication Critical patent/DE69021470T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G01N33/5304—Reaction vessels, e.g. agglutination plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0661—Valves, specific forms thereof with moving parts shape memory polymer valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Reproductive Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Jet Pumps And Other Pumps (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
DE69021470T 1989-03-23 1990-03-23 Transfervorrichtung für flüssigkeiten. Expired - Fee Related DE69021470T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898906833A GB8906833D0 (en) 1989-03-23 1989-03-23 Liquid transfer devices
GB898922513A GB8922513D0 (en) 1989-10-06 1989-10-06 Liquid transfer devices
PCT/GB1990/000441 WO1990011519A1 (en) 1989-03-23 1990-03-23 Liquid transfer devices

Publications (2)

Publication Number Publication Date
DE69021470D1 DE69021470D1 (de) 1995-09-14
DE69021470T2 true DE69021470T2 (de) 1996-01-25

Family

ID=26295133

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021470T Expired - Fee Related DE69021470T2 (de) 1989-03-23 1990-03-23 Transfervorrichtung für flüssigkeiten.

Country Status (9)

Country Link
US (2) US5198193A (de)
EP (2) EP0590695A3 (de)
JP (1) JPH03505261A (de)
AT (1) ATE126353T1 (de)
DE (1) DE69021470T2 (de)
DK (1) DK0417243T3 (de)
GB (1) GB2231150B (de)
IE (2) IE940110L (de)
WO (1) WO1990011519A1 (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234813A (en) * 1989-05-17 1993-08-10 Actimed Laboratories, Inc. Method and device for metering of fluid samples and detection of analytes therein
US5807747A (en) * 1989-06-13 1998-09-15 Clinical Innovations Limited Method and apparatus for determination of glycosylated protein
GB9123903D0 (en) * 1991-11-11 1992-01-02 Bunce Roger A Liquid transfer assay devices
US5540888A (en) * 1991-11-11 1996-07-30 British Technology Group Limited Liquid transfer assay devices
GB9123922D0 (en) * 1991-11-11 1992-01-02 Bunce Roger A Liquid transfer devices
GB9304452D0 (en) * 1993-03-04 1993-04-21 Bunce Roger A Analytical devices
GB9307319D0 (en) * 1993-04-07 1993-06-02 British Tech Group Liquid transfer devices
DE4323672A1 (de) * 1993-07-15 1995-01-19 Boehringer Mannheim Gmbh Vorrichtung zur gleichzeitigen Bestimmung von Analyten
GB9324310D0 (en) * 1993-11-26 1994-01-12 Univ Birmingham Liquid transfer device
GB9416002D0 (en) * 1994-08-08 1994-09-28 Univ Cranfield Fluid transport device
GB9502112D0 (en) * 1995-02-03 1995-03-22 British Biocell Int Assay device and method
CA2228485A1 (en) * 1995-08-03 1997-02-20 Akzo Nobel Nv Diagnostic device
US5849598A (en) * 1996-03-15 1998-12-15 Washington University Method for transferring micro quantities of liquid samples to discrete locations
CH690628A5 (de) * 1996-03-22 2000-11-15 Intex Pharmazeutische Produkte Testbesteck, bestehend aus einem Blister, und seine Verwendung.
GB9709821D0 (en) * 1997-05-15 1997-07-09 Clinical Diagnostic Chemicals Allergy assay
US6375901B1 (en) * 1998-06-29 2002-04-23 Agilent Technologies, Inc. Chemico-mechanical microvalve and devices comprising the same
US6270644B1 (en) * 1999-01-27 2001-08-07 Affymetrix, Inc. Capillary array electrophoresis scanner
DE19915811C2 (de) * 1999-04-08 2001-05-03 Boehringer Ingelheim Pharma Reaktionsgefäß
FR2793186B1 (fr) 1999-05-04 2001-06-15 Vetrotex France Sa Produits composites creux et procede de fabrication
DE19919608A1 (de) 1999-05-27 2000-11-30 Roche Diagnostics Gmbh Probenträger für die IR-Spetktroskopie von Probenflüssigkeiten
GB9923384D0 (en) * 1999-10-05 1999-12-08 Univ Birmingham Fluid-flow control device
US6471917B1 (en) * 2000-04-11 2002-10-29 Affymax, Inc. System and method for single or multiple bead distribution with an adjustable capillary
US6436722B1 (en) * 2000-04-18 2002-08-20 Idexx Laboratories, Inc. Device and method for integrated diagnostics with multiple independent flow paths
US7879293B2 (en) * 2001-09-28 2011-02-01 Orasure Technologies, Inc. Sample collector and test device
JP2005532827A (ja) * 2002-07-12 2005-11-04 ブリティッシュ・バイオセル・インターナショナル・リミテッド 側方フローアッセイ用のデバイスおよびその方法
US7396512B2 (en) * 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US7879567B2 (en) * 2004-10-05 2011-02-01 Asahi Kasei Pharma Corporation Method for stabilizing coenzyme and composition therefor
EP3028765B1 (de) 2005-01-31 2020-01-08 Realbio Technologies Ltd. Methode zum sequenziellen transferieren von flüssigkeiten durch eine querstromkapillarvorrichtung
DE102005017653A1 (de) 2005-04-15 2006-10-19 Boehringer Ingelheim Microparts Gmbh Vorrichtung und Verfahren zur Manipulation einer Flüssigkeit
US7955558B2 (en) 2005-11-09 2011-06-07 Koninklijke Philips Electronics N.V. Device for testing a fluid
WO2008105814A2 (en) 2006-08-22 2008-09-04 Los Alamos National Security, Llc Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
US8980561B1 (en) 2006-08-22 2015-03-17 Los Alamos National Security, Llc. Nucleic acid detection system and method for detecting influenza
GB0617035D0 (en) * 2006-08-30 2006-10-11 Inverness Medical Switzerland Fluidic indicator device
EP1933146B1 (de) 2006-12-11 2011-08-24 AraGen Biotechnology Co. Ltd. Schnelle immunchromatographische Detektion durch Verstärkung des kolloidalen Gold Signals
EP1933147B1 (de) * 2006-12-11 2011-08-17 AraGen Biotechnology Co. Ltd. Schnelle immunochromatographische Detektion durch Verstärkung des kolloidalen Gold Signals
EP1933142B1 (de) * 2006-12-11 2011-08-17 AraGen Biotechnology Co. Ltd. Schnelle immunochromatographische Detektion durch Verstärkung des kolloidalen Gold Signals
EP1933144B1 (de) * 2006-12-11 2011-09-28 AraGen Biotechnology Co. Ltd. Schnelle immunochromatographische Detektion durch Verstärkung des kolloidalen Gold Signals
EP1933143B1 (de) * 2006-12-11 2011-08-17 AraGen Biotechnology Co. Ltd. Schnelle immunochromatographische Detektion durch Verstärkung des kolloidalen Gold Signals
EP1933145B1 (de) 2006-12-11 2011-09-28 AraGen Biotechnology Co. Ltd. Schnelle immunochromatographische Detektion durch Verstärkung des kolloidalen Gold Signals
WO2009137059A1 (en) * 2008-05-05 2009-11-12 Los Alamos National Security, Llc Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
US9952211B2 (en) 2008-06-29 2018-04-24 Realbio Technologies Ltd. Liquid-transfer device particularly useful as a capturing device in a biological assay process
AU2009281693B2 (en) 2008-08-14 2015-08-27 Monash University Switches for microfluidic systems
WO2011027092A1 (en) * 2009-09-01 2011-03-10 F. Hoffmann-La Roche Ag Micro-fluidic structures
US20120288961A1 (en) * 2009-12-22 2012-11-15 University Of Washington Capillarity-based devices for performing chemical processes and associated systems and methods
WO2012145725A2 (en) 2011-04-20 2012-10-26 Mesa Tech International, Inc. Oscillating amplification reaction for nucleic acids
WO2012178187A1 (en) * 2011-06-23 2012-12-27 Paul Yager Reagent patterning in capillarity-based analyzers and associated systems and methods
US20140134631A1 (en) * 2011-07-04 2014-05-15 National Research Council Of Canada Centrifugal microfluidic platform
CN105833925B (zh) 2011-12-22 2018-11-13 瑞尔比奥技术有限公司 用于分析物测定的序贯侧向流动毛细管装置
JP6177529B2 (ja) 2012-01-20 2017-08-09 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． 多数の試薬セルを有するアッセイ装置
CN107884560A (zh) 2012-04-04 2018-04-06 辛辛那提大学 汗液模拟、收集和感测系统
US20140093980A1 (en) * 2012-10-01 2014-04-03 University Of Washington Through Its Center For Commercialization Dissolvable bridges for manipulating fluid volumes and associated devices, systems and methods
US9724689B2 (en) * 2012-11-20 2017-08-08 Detectachem Llc Colorimetric test system designed to control flow of simultaneously released chemicals to a target area
WO2014116756A1 (en) 2013-01-22 2014-07-31 University Of Washington Through Its Center For Commercialization Sequential delivery of fluid volumes and associated devices, systems and methods
EP2767831A1 (de) * 2013-02-19 2014-08-20 DST Diagnostische Systeme & Technologien GmbH Neues PoC-Testsystem und Verfahren
US10031100B2 (en) * 2013-03-13 2018-07-24 Robert Bosch Gmbh Generation of pH/temperature/ionic gradients on a lateral flow platform with multiple parallel lanes for modulating protein interactions
CN110477861B (zh) 2013-10-18 2023-02-03 辛辛那提大学 以确保时间顺序方式的汗液感测
CA2927211A1 (en) 2013-10-18 2015-04-23 University Of Cincinnati Devices for integrated, repeated, prolonged, and/or reliable sweat stimulation and biosensing
US10888244B2 (en) 2013-10-18 2021-01-12 University Of Cincinnati Sweat sensing with chronological assurance
JP2017522924A (ja) 2014-05-28 2017-08-17 ユニバーシティ・オブ・シンシナティ センサと汗腺との間で減少した汗体積を備える装置
WO2015184072A1 (en) 2014-05-28 2015-12-03 University Of Cincinnati Advanced sweat sensor adhesion, sealing, and fluidic strategies
JP2017518814A (ja) 2014-05-28 2017-07-13 ユニバーシティ・オブ・シンシナティ 発汗モニタリング及び薬物送達の制御
CN107205643B (zh) 2014-09-22 2021-11-23 辛辛那提大学 具有分析保证的汗液传感
EP3206569A2 (de) 2014-10-15 2017-08-23 Eccrine Systems, Inc. Kommunikationssicherheit und -konformität für schweisserfassungsvorrichtung
EP3256049A4 (de) 2015-02-13 2018-07-25 University of Cincinnati Vorrichtungen zur integrierten indirekten schweissstimulation und -messung
US10646142B2 (en) 2015-06-29 2020-05-12 Eccrine Systems, Inc. Smart sweat stimulation and sensing devices
WO2017070640A1 (en) 2015-10-23 2017-04-27 Eccrine Systems, Inc. Devices capable of sample concentration for extended sensing of sweat analytes
US10674946B2 (en) 2015-12-18 2020-06-09 Eccrine Systems, Inc. Sweat sensing devices with sensor abrasion protection
US10471249B2 (en) 2016-06-08 2019-11-12 University Of Cincinnati Enhanced analyte access through epithelial tissue
US11253190B2 (en) 2016-07-01 2022-02-22 University Of Cincinnati Devices with reduced microfluidic volume between sensors and sweat glands
EP3487390A4 (de) 2016-07-19 2020-03-11 Eccrine Systems, Inc. Vorrichtungen sowie anwendungen für schweissleitfähigkeit, volumetrische schweissrate und galvanische hautreaktion
WO2018022458A1 (en) 2016-07-25 2018-02-01 Bio-Rad Laboratories, Inc. Lateral flow device and method of use
US10736565B2 (en) 2016-10-14 2020-08-11 Eccrine Systems, Inc. Sweat electrolyte loss monitoring devices
US10688487B2 (en) 2016-11-23 2020-06-23 Bio-Rad Laboratories, Inc. Lateral flow assay device
US10883987B2 (en) 2017-01-27 2021-01-05 Bio-Rad Laboratories, Inc. Lateral flow device
EP3717910A4 (de) 2017-11-28 2021-12-15 Bio-Rad Laboratories, Inc. Lateral-flow-test-vorrichtung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
JPH06103300B2 (ja) * 1986-03-25 1994-12-14 ピービー ダイアグノスティック システムズ，インコーポレーテッド 生物学的診断装置
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
GB8725458D0 (en) * 1987-10-30 1987-12-02 Unilever Plc Chemical testing

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EP0590695A2 (de) 1994-04-06
ATE126353T1 (de) 1995-08-15
JPH03505261A (ja) 1991-11-14
DE69021470D1 (de) 1995-09-14
EP0417243A1 (de) 1991-03-20
US5354538A (en) 1994-10-11
IE940110L (en) 1990-09-23
GB2231150B (en) 1993-10-13
EP0590695A3 (en) 1994-07-13
GB2231150A (en) 1990-11-07
GB9006575D0 (en) 1990-05-23
IE901062L (en) 1990-09-23
EP0417243B1 (de) 1995-08-09
IE69047B1 (en) 1996-08-07
US5198193A (en) 1993-03-30
DK0417243T3 (da) 1995-09-18
IE901062A1 (en) 1991-06-19
WO1990011519A1 (en) 1990-10-04

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