DE69015314T2 - Verwendung von adenylzyclase als vakzin gegen bordetella. - Google Patents

Verwendung von adenylzyclase als vakzin gegen bordetella.

Info

Publication number
DE69015314T2
DE69015314T2 DE69015314T DE69015314T DE69015314T2 DE 69015314 T2 DE69015314 T2 DE 69015314T2 DE 69015314 T DE69015314 T DE 69015314T DE 69015314 T DE69015314 T DE 69015314T DE 69015314 T2 DE69015314 T2 DE 69015314T2
Authority
DE
Germany
Prior art keywords
vaccine against
adenyl cyclase
against bordetella
bordetella species
bordetella
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69015314T
Other languages
English (en)
Other versions
DE69015314D1 (de
Inventor
Nicole Guiso-Maclouf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of DE69015314D1 publication Critical patent/DE69015314D1/de
Application granted granted Critical
Publication of DE69015314T2 publication Critical patent/DE69015314T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
DE69015314T 1989-05-12 1990-05-11 Verwendung von adenylzyclase als vakzin gegen bordetella. Expired - Lifetime DE69015314T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8906321A FR2646776B1 (fr) 1989-05-12 1989-05-12 Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella
PCT/FR1990/000337 WO1990013312A1 (fr) 1989-05-12 1990-05-11 Utilisation d'adenyl cyclase ou de bacteries le produisant, comme vaccins contre bordetella

Publications (2)

Publication Number Publication Date
DE69015314D1 DE69015314D1 (de) 1995-02-02
DE69015314T2 true DE69015314T2 (de) 1996-11-28

Family

ID=9381646

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69015314T Expired - Lifetime DE69015314T2 (de) 1989-05-12 1990-05-11 Verwendung von adenylzyclase als vakzin gegen bordetella.

Country Status (10)

Country Link
US (3) US6214356B1 (de)
EP (1) EP0424518B1 (de)
JP (1) JP3399525B2 (de)
AT (1) ATE115861T1 (de)
CA (1) CA2033085C (de)
DE (1) DE69015314T2 (de)
ES (1) ES2066206T3 (de)
FR (1) FR2646776B1 (de)
PT (1) PT94030B (de)
WO (1) WO1990013312A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2646776B1 (fr) 1989-05-12 1994-06-03 Pasteur Institut Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella
FR2728170A1 (fr) * 1994-12-15 1996-06-21 Pasteur Institut Vaccin de type acellulaire anti-bordetella
US6030625A (en) * 1994-12-15 2000-02-29 Institut Pasteur Bordetella pertussis and Bordetella parapertussis strains
FR2736064B1 (fr) 1995-06-30 1997-09-05 Pasteur Institut Epitopes protecteurs de l'adenyl cyclase-hemolysine(ac-hty). leur application au traitement ou a la prevention des infections par bordetella
US7462472B2 (en) * 2001-11-02 2008-12-09 The University Of Chicago Methods and compositions relating to anthrax pathogenesis
WO2005032584A2 (en) 2003-10-02 2005-04-14 Glaxosmithkline Biologicals S.A. Pertussis antigens and use thereof in vaccination
US7521059B2 (en) * 2004-06-14 2009-04-21 Fenwick Bradley W Kennel cough vaccine

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
US5237052A (en) 1984-05-12 1993-08-17 Burroughs Wellcome Company Antigenic preparations and isolation of such preparations
US4652521A (en) * 1985-03-04 1987-03-24 Regents Of The University Of Minnesota Method for the early diagnosis of bordetella diseases and kit therefor
FR2590483B1 (fr) * 1985-11-22 1988-12-09 Pasteur Institut Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
FR2606789B1 (fr) * 1986-11-17 1991-05-31 Pasteur Institut Preparations d'adenylate cyclase purifiees, procede d'obtention de ces preparations et leurs applications biologiques
EP0267998A1 (de) * 1986-11-17 1988-05-25 Institut Pasteur Mittel zur Unterstützung gegen Infektion und Vergiftung von Bordetella
FR2621597B1 (fr) 1987-07-24 1992-07-31 Pasteur Institut Procede de clonage et d'expression de genes codant pour des proteines constituant des edifices fonctionnels organises
ATE140729T1 (de) * 1988-04-19 1996-08-15 Pasteur Institut Verfahren zur gewinnung von schutzantigenen gegen bordetella-infektionen und toxische prozesse
EP0338170A1 (de) * 1988-04-19 1989-10-25 Institut Pasteur Immunschutz gewährendes antigenes Protein gegen pathogene Bakterien
FR2638169B1 (fr) * 1988-10-25 1991-01-11 Pasteur Institut Derives d'adenyl cyclase et leurs utilisations biologiques
FR2646776B1 (fr) * 1989-05-12 1994-06-03 Pasteur Institut Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella
ATE121754T1 (de) * 1989-09-04 1995-05-15 Wellcome Found Vakzine gegen bordetella.
US5786189A (en) * 1989-11-29 1998-07-28 Smithkline Beecham Biologicals (S.A.) Vaccine
HU219819B (hu) * 1992-08-18 2001-08-28 Dimminaco Ag/Sa/Ltd. Izolált polinukleotidok, ezeket tartalmazó Bordetella bronchiseptica törzs, és Bordetella bronchiseptica elleni vakcina
US6030625A (en) * 1994-12-15 2000-02-29 Institut Pasteur Bordetella pertussis and Bordetella parapertussis strains
FR2728170A1 (fr) * 1994-12-15 1996-06-21 Pasteur Institut Vaccin de type acellulaire anti-bordetella
EP1233022B1 (de) * 1995-05-04 2015-12-09 Aventis Pasteur Limited Verfahren zur Herstellung von Komponenten azellulären Pertussis-Impfstoffen
FR2736064B1 (fr) * 1995-06-30 1997-09-05 Pasteur Institut Epitopes protecteurs de l'adenyl cyclase-hemolysine(ac-hty). leur application au traitement ou a la prevention des infections par bordetella
GB9718901D0 (en) * 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
ES2303833T3 (es) * 2000-05-25 2008-09-01 Institut Pasteur Polipeptidos que contienen polimorfismos de las regiones repetidas de pertactina en bordetella pertussis, bordetella parapertussis y bordetella bronchiseptica, su uso en diagnostico y en composiciones inmunogenicas.
EP1188446B1 (de) 2000-09-15 2009-08-05 Institut Pasteur Proteinhaltigen Vektoren zur Einführung von Moleküle in CD11b exprimirende Zellen

Also Published As

Publication number Publication date
US20030224003A1 (en) 2003-12-04
US6214356B1 (en) 2001-04-10
JPH03506044A (ja) 1991-12-26
CA2033085A1 (fr) 1990-11-13
PT94030A (pt) 1991-01-08
US7211263B2 (en) 2007-05-01
JP3399525B2 (ja) 2003-04-21
CA2033085C (fr) 2003-07-22
ATE115861T1 (de) 1995-01-15
EP0424518A1 (de) 1991-05-02
WO1990013312A1 (fr) 1990-11-15
PT94030B (pt) 1997-07-31
FR2646776B1 (fr) 1994-06-03
DE69015314D1 (de) 1995-02-02
FR2646776A1 (fr) 1990-11-16
ES2066206T3 (es) 1995-03-01
EP0424518B1 (de) 1994-12-21
US20020172691A1 (en) 2002-11-21

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition