DE69007616T2 - Peptid, immunogene zusammensetzung und impfstoff oder medizinische zubereitung, eine methode zur immunisierung eines säugetieres gegen lhrh und methode zur verbesserung von mea. - Google Patents

Peptid, immunogene zusammensetzung und impfstoff oder medizinische zubereitung, eine methode zur immunisierung eines säugetieres gegen lhrh und methode zur verbesserung von mea.

Info

Publication number
DE69007616T2
DE69007616T2 DE69007616T DE69007616T DE69007616T2 DE 69007616 T2 DE69007616 T2 DE 69007616T2 DE 69007616 T DE69007616 T DE 69007616T DE 69007616 T DE69007616 T DE 69007616T DE 69007616 T2 DE69007616 T2 DE 69007616T2
Authority
DE
Germany
Prior art keywords
peptide
mammaly
immunogenous
immunizing
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69007616T
Other languages
English (en)
Other versions
DE69007616D1 (de
Inventor
Robert H Meloen
Cornelis J G Wensing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pepscan Systems BV
Original Assignee
Stichting Centraal Diergeneeskundig Instituut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Centraal Diergeneeskundig Instituut filed Critical Stichting Centraal Diergeneeskundig Instituut
Publication of DE69007616D1 publication Critical patent/DE69007616D1/de
Application granted granted Critical
Publication of DE69007616T2 publication Critical patent/DE69007616T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0006Contraceptive vaccins; Vaccines against sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/62Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
DE69007616T 1989-03-23 1990-03-22 Peptid, immunogene zusammensetzung und impfstoff oder medizinische zubereitung, eine methode zur immunisierung eines säugetieres gegen lhrh und methode zur verbesserung von mea. Expired - Lifetime DE69007616T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8900726A NL8900726A (nl) 1989-03-23 1989-03-23 Peptide, immunogene samenstelling en vaccin- of geneesmiddelpreparaat; werkwijze voor het immuniseren van een zoogdier tegen lhrh, en werkwijze voor het verbeteren van de vleeskwaliteit van varkens.
PCT/NL1990/000037 WO1990011298A1 (en) 1989-03-23 1990-03-22 A peptide, immunogenic composition and vaccine or medicinal preparation; a method of immunising a mammal against lhrh, and a method of improving the meat quality of pigs

Publications (2)

Publication Number Publication Date
DE69007616D1 DE69007616D1 (de) 1994-04-28
DE69007616T2 true DE69007616T2 (de) 1994-06-30

Family

ID=19854349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69007616T Expired - Lifetime DE69007616T2 (de) 1989-03-23 1990-03-22 Peptid, immunogene zusammensetzung und impfstoff oder medizinische zubereitung, eine methode zur immunisierung eines säugetieres gegen lhrh und methode zur verbesserung von mea.

Country Status (11)

Country Link
EP (1) EP0464124B1 (de)
JP (1) JP3098771B2 (de)
AT (1) ATE103297T1 (de)
CA (1) CA2049325C (de)
DE (1) DE69007616T2 (de)
DK (1) DK0464124T3 (de)
ES (1) ES2050435T3 (de)
HU (1) HU214742B (de)
NL (1) NL8900726A (de)
RU (1) RU2078770C1 (de)
WO (1) WO1990011298A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8713240D0 (en) * 1987-06-05 1987-07-08 Proteus Biotech Ltd Hormones
US5171835A (en) * 1988-10-21 1992-12-15 The Administrators Of The Tulane Educational Fund LHRH antagonists
US5324512A (en) * 1990-12-26 1994-06-28 The Population Council [Gln']-luteinizing hormone releasing hormone conjugate of tetanus vaccine and its uses
PL296623A1 (en) * 1991-03-01 1993-09-20 Rhone Merieux Method of improving organoleptic properties of male slaughter animal meat
US5837268A (en) * 1991-10-16 1998-11-17 University Of Saskatchewan GnRH-leukotoxin chimeras
US5723129A (en) * 1991-10-16 1998-03-03 University Of Saskatchewan GnRH-leukotoxin chimeras
ZA934199B (en) * 1992-06-18 1994-01-10 Akzo Nv Carrier system against gnrh
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
US6761890B1 (en) 1995-06-07 2004-07-13 Pepscan Systems B.V. Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine
JP3959746B2 (ja) * 1995-06-07 2007-08-15 ペプスキャン システムズ ベー.フェー. 改良ペプチド、免疫原性組成物およびワクチンまたは医薬製剤、lhrhホルモンに対する動物の免疫方法、ならびにlhrh縦列反復ペプチドおよびそのワクチンとしての使用
US5885966A (en) * 1995-06-07 1999-03-23 Dlo Instituut Voor Dierhouderij En Diergezondheid Peptide, immunogenic composition and vaccine or medical preparation, a method to immunise animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine
JP4651753B2 (ja) * 1996-06-25 2011-03-16 ペプスキャン システムズ ベー.フェー. 不安定結合による担体結合抗原から成るワクチン
AUPO776897A0 (en) 1997-07-09 1997-07-31 Csl Limited A method of achieving production gains in livestock and agents useful for same
AU771556B2 (en) * 1998-06-04 2004-03-25 Metamorphix International, Inc. Methods for suppressing reproductive behavior in animals
US6838553B1 (en) * 1999-10-05 2005-01-04 Academia Sinica Peptide repeat immunogens
SG173223A1 (en) 2003-04-22 2011-08-29 Ipsen Pharma Sas Peptide vectors
CU23739A1 (es) 2008-09-30 2011-12-28 Ct Ingenieria Genetica Biotech Composición farmacéutica utilizando combinaciones de variantes de la hormona liberadora de las gonadotropinas (gnrh) como inmunógeno
RU2521652C2 (ru) * 2010-12-27 2014-07-10 Общество с ограниченной ответственностью "Научно-внедренческое предприятие "Астрафарм" РЕКОМБИНАНТНАЯ ДНК, КОДИРУЮЩАЯ ГИБРИДНЫЙ ВАКЦИННЫЙ БЕЛОК GHbc ДЛЯ РЕГУЛЯЦИИ ПОЛОВОЙ ФУНКЦИИ У ЖИВОТНЫХ, СОСТОЯЩИЙ ИЗ НУКЛЕОКАПСИДНОГО БЕЛКА ВИРУСА ГЕПАТИТА В ЧЕЛОВЕКА СЛИТОГО С ГОНАДОЛИБЕРИНОМ
RU2529959C1 (ru) * 2013-10-09 2014-10-10 Общество с ограниченной ответственностью ООО "Нанолек" Иммунологический адъювант на основе наночастиц для вакцин против высокопатогенных штаммов вируса гриппа
WO2016014071A1 (en) * 2014-07-25 2016-01-28 United Biomedical, Inc Immunogenic lhrh composition and use thereof in pigs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608251A (en) * 1984-11-09 1986-08-26 Pitman-Moore, Inc. LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues
WO1988005308A1 (en) * 1987-01-14 1988-07-28 Commonwealth Scientific And Industrial Research Or Anti reproductive hormone

Also Published As

Publication number Publication date
CA2049325A1 (en) 1990-09-24
CA2049325C (en) 2000-07-25
JPH04504256A (ja) 1992-07-30
DK0464124T3 (da) 1994-05-02
HU902930D0 (en) 1991-12-30
DE69007616D1 (de) 1994-04-28
HUT62916A (en) 1993-06-28
JP3098771B2 (ja) 2000-10-16
ATE103297T1 (de) 1994-04-15
EP0464124A1 (de) 1992-01-08
HU214742B (hu) 1998-10-28
EP0464124B1 (de) 1994-03-23
RU2078770C1 (ru) 1997-05-10
NL8900726A (nl) 1990-10-16
ES2050435T3 (es) 1994-05-16
WO1990011298A1 (en) 1990-10-04

Similar Documents

Publication Publication Date Title
DE69007616D1 (de) Peptid, immunogene zusammensetzung und impfstoff oder medizinische zubereitung, eine methode zur immunisierung eines säugetieres gegen lhrh und methode zur verbesserung von mea.
BR9814473A (pt) Imunógenos anti-retrovirais, preparação e uso
HUP9901186A2 (hu) Peptid-és adjuvánsalapú gyógyszerkészítmény immunmodulációra
ES2178000T3 (es) Composiciones y metodos para tratar infecciones usando analogos de indolicidina.
ATE127345T1 (de) Stressproteine und verwendungen dafür.
AR018603A1 (es) Un peptido, util para el tratamiento y/o profilaxis de la enfermedad de alzheimer y el sindrome de down, las composiciones farmaceuticas y vacunas que locontienen, el uso de dicho peptido para la preparacion de las composiciones farmaceuticas, una secuencia de aislado de adn, un plasmido o vector vi
ATE512231T1 (de) Impfstoffe, immuntherapeutika und verfahren zur anwendung derselben
RU2002103604A (ru) Антигенные менингококковые пептиды
RU2001134170A (ru) Антигенные пептиды NEISSERIA
DE69101634D1 (de) Rekombinant hergestellte blutfaktoren, verfahren zur exprimierung besagter blutfaktoren sowie in besagtem prozess verwendeter rekombinanter vaccina-virus.
BR0010155A (pt) Proteìnas isolada, e quimérica, composição, molécula de ácido nucleico, plasmìdeo, vacina recombinante ou vacina atenuada, composição de vacina recombinante ou composição de vacina atenuada, composição farmacêutica, métodos de imunizar um indivìduo contra um imunógeno, proteìna não-cd80 isolada, molécula de ácido nucleico, e, método de imunossuprimir um indivìduo
BR9506272A (pt) Análogo isolado e purificado de proteina hin 47 haemophilus influenzae moçécula quimérica molécula de ácido nucleico purificada e isolada plasmídeo recombinante célula tranformada processo para produzir um análogo de porteina hin 47 haemophilus influenzae composicão imunogênica processo para determinir a presença de anticorpos processo para determinir a presença de proteina hin 47 em uma amostra e estojo diagnóstico hin 47
ATE205219T1 (de) Ein verbessertes peptid, immunogene zusammensetzung und impfstoff oder medizinische präparate, eine methode zur immunisierung von tieren gegen das hormon lhrh und analoge des lhrh-tendem-repeat-peptid und deren verwendung als impfstoff
DE3584775D1 (de) Zusammensetzung zur behandlung von an haemophilia-a-inhibitor leidenden kranken.
US7638481B2 (en) Treatment of spinal cord injury
FR2746110B1 (fr) Methode de traitement par therapie genique des tumeurs humaines et virus recombinants correspondants
EP0236977A3 (de) Impfstoffe gegen Rindervirus-Diarrhoe und Schweine-Cholera
ATE310747T1 (de) Impfstoff gegen geflügelkokzidose
DE69432137D1 (de) Impfstoff gegen Geflügelkokzidose
DE69521007D1 (de) Impfstoff gegen Geflügelkokzidose
DK0938329T3 (da) Immunogen TLP sammensætning
BR0012740A (pt) Compostos para tratamento de distúrbios do sistema infeccioso e imune e métodos para seu emprego
AR030293A1 (es) Una composicion de vacuna que comprende una proteina receptora de fc; un metodo para prepararla; uso de dicha proteina y de un polinucleotido que codifica para dicha proteina y un metodo para tratar o prevenir una infeccion bacteriana
Purcell et al. Approaches to the development of hepatitis-A vaccines: The old and the new.
DE60040910D1 (de) Inaktivierte zytokine zur immunisierung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BLUMBACH, KRAMER & PARTNER, 65193 WIESBADEN

8327 Change in the person/name/address of the patent owner

Owner name: PEPSCAN SYSTEMS B.V., LELYSTAD, NL