DE69006338T2 - Neue Derivate substituierter Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, die sie enthalten. - Google Patents

Neue Derivate substituierter Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, die sie enthalten.

Info

Publication number
DE69006338T2
DE69006338T2 DE69006338T DE69006338T DE69006338T2 DE 69006338 T2 DE69006338 T2 DE 69006338T2 DE 69006338 T DE69006338 T DE 69006338T DE 69006338 T DE69006338 T DE 69006338T DE 69006338 T2 DE69006338 T2 DE 69006338T2
Authority
DE
Germany
Prior art keywords
group
denotes
substituted
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69006338T
Other languages
English (en)
Other versions
DE69006338D1 (de
Inventor
Michel Vincent
Georges Remond
Bernard Portevin
Yolande Herve
Jean Lepagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE69006338D1 publication Critical patent/DE69006338D1/de
Application granted granted Critical
Publication of DE69006338T2 publication Critical patent/DE69006338T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69006338T 1989-12-20 1990-12-20 Neue Derivate substituierter Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, die sie enthalten. Expired - Fee Related DE69006338T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8916881A FR2655989B1 (fr) 1989-12-20 1989-12-20 Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
DE69006338D1 DE69006338D1 (de) 1994-03-10
DE69006338T2 true DE69006338T2 (de) 1994-08-18

Family

ID=9388750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69006338T Expired - Fee Related DE69006338T2 (de) 1989-12-20 1990-12-20 Neue Derivate substituierter Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, die sie enthalten.

Country Status (15)

Country Link
US (1) US5151432A (de)
EP (1) EP0434560B1 (de)
JP (1) JPH07121908B2 (de)
AT (1) ATE100818T1 (de)
AU (1) AU625406B2 (de)
CA (1) CA2032735A1 (de)
DE (1) DE69006338T2 (de)
DK (1) DK0434560T3 (de)
ES (1) ES2062469T3 (de)
FR (1) FR2655989B1 (de)
IE (1) IE66009B1 (de)
NZ (1) NZ236233A (de)
OA (1) OA09476A (de)
PT (1) PT96254A (de)
ZA (1) ZA909766B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946993A (en) * 1988-11-23 1990-08-07 American Cyanamid Company 2-azabicyclo[2.2.1.]hept-5-ene-2-acetic acid, derivatives thereof and related compounds, process for the preparation of said compounds, and the use of said compounds for the manufacture of N-phosphonomethylglycine
FR2672598A1 (fr) * 1991-02-11 1992-08-14 Adir Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO1995029892A1 (en) * 1994-04-28 1995-11-09 The Du Pont Merck Pharmaceutical Company Hydroxamic acid and amino acid derivatives and their use as anti-arthritic agents
HUP0003982A3 (en) * 1997-10-17 2002-01-28 Eurogene Ltd The use of inhibitors of the renin-angiotensin system for producing pharmaceutical compositions using for the treatment of hypoxia or impaired metabolic function

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
DE3246757A1 (de) * 1982-12-17 1984-06-20 Hoechst Ag, 6230 Frankfurt Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung
CA1321753C (en) * 1987-04-27 1993-08-31 Abraham Sudilovsky Method for inhibiting loss of cognitive functions employing an ace inhibitor
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
DE69006338D1 (de) 1994-03-10
JPH07121908B2 (ja) 1995-12-25
AU625406B2 (en) 1992-07-09
ATE100818T1 (de) 1994-02-15
DK0434560T3 (da) 1994-03-28
EP0434560A1 (de) 1991-06-26
PT96254A (pt) 1991-09-30
ES2062469T3 (es) 1994-12-16
FR2655989B1 (fr) 1992-02-28
US5151432A (en) 1992-09-29
OA09476A (fr) 1992-11-15
FR2655989A1 (fr) 1991-06-21
AU6823490A (en) 1991-06-27
ZA909766B (en) 1991-09-25
IE66009B1 (en) 1995-11-29
EP0434560B1 (de) 1994-01-26
IE904586A1 (en) 1991-07-03
CA2032735A1 (fr) 1991-06-21
JPH05320131A (ja) 1993-12-03
NZ236233A (en) 1992-07-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee