DE69128231D1 - Heterozyklische Alkylamine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten - Google Patents

Heterozyklische Alkylamine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten

Info

Publication number
DE69128231D1
DE69128231D1 DE69128231T DE69128231T DE69128231D1 DE 69128231 D1 DE69128231 D1 DE 69128231D1 DE 69128231 T DE69128231 T DE 69128231T DE 69128231 T DE69128231 T DE 69128231T DE 69128231 D1 DE69128231 D1 DE 69128231D1
Authority
DE
Germany
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
alkyl amines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69128231T
Other languages
English (en)
Other versions
DE69128231T2 (de
Inventor
Thierry Taverne
Isabelle Lesieur
Patrick Depreux
Daniel Henri Caignard
Beatrice Guardiola
Gerard Adam
Pierre Renard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of DE69128231D1 publication Critical patent/DE69128231D1/de
Publication of DE69128231T2 publication Critical patent/DE69128231T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE69128231T 1990-09-26 1991-09-25 Heterozyklische Alkylamine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten Expired - Fee Related DE69128231T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909011866A FR2667068B1 (fr) 1990-09-26 1990-09-26 Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
DE69128231D1 true DE69128231D1 (de) 1998-01-02
DE69128231T2 DE69128231T2 (de) 1998-06-18

Family

ID=9400666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69128231T Expired - Fee Related DE69128231T2 (de) 1990-09-26 1991-09-25 Heterozyklische Alkylamine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten

Country Status (15)

Country Link
US (3) US5225409A (de)
EP (1) EP0478446B1 (de)
JP (1) JPH0786097B2 (de)
AT (1) ATE160344T1 (de)
AU (1) AU644212B2 (de)
CA (1) CA2052234A1 (de)
DE (1) DE69128231T2 (de)
DK (1) DK0478446T3 (de)
ES (1) ES2111556T3 (de)
FR (1) FR2667068B1 (de)
GR (1) GR3025948T3 (de)
IE (1) IE913363A1 (de)
NZ (1) NZ239929A (de)
PT (1) PT99055B (de)
ZA (1) ZA917701B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4037427A1 (de) * 1990-11-24 1992-05-27 Kali Chemie Pharma Gmbh Heterocyclisch substituierte piperazinoalkylbenzoxazin und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2702214B1 (fr) * 1993-03-05 1995-04-14 Adir Nouveaux composés (aryl(alkyl)carbonyl)-hétérocycliques, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
FI951296A (fi) * 1994-03-22 1995-09-23 Adir Uudet aminoalkyylibentsotiatsolinonit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FR2717810B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2717807B1 (fr) * 1994-03-22 1996-04-19 Adir Nouvelles 6- [(4-arylalkyl-1-piperazino)alkyl] benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2717806B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelle aminoalkyl benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5567718A (en) * 1994-08-11 1996-10-22 Hoechst Marion Roussel Inc. 2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors
US5998467A (en) * 1995-10-25 1999-12-07 Mitsubishi Chemical Corporation Medicine for oculopathy
US6177422B1 (en) 1996-05-29 2001-01-23 Warner-Lambert Company Benzoxazinone dopamine D4 receptor antagonists
WO1998018458A1 (en) * 1996-10-31 1998-05-07 Alcon Laboratories, Inc. Opthalmological compositions containing serotonin 5-ht1a receptor agonist and their use in the treatment of glaucoma
FR2755690B1 (fr) * 1996-11-08 1998-12-18 Adir Nouveaux derives aminomethyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6387904B2 (en) * 1998-05-18 2002-05-14 Pfizer Inc Method of treating glaucoma and ischemic retinopathy
US20040192669A1 (en) 2000-04-13 2004-09-30 Rosenfeld Mark J. Novel compounds for use in weight loss and appetite suppression in humans
US7794761B2 (en) 2000-04-13 2010-09-14 Seroctin Research & Technology, Inc. Methods for inducing anti-anxiety and calming effects in animals and humans
DK1399438T3 (da) * 2001-06-29 2006-04-18 Lundbeck & Co As H Hidtil ukendte heteroarylderivater samt fremstilling og anvendelse heraf
AU2003293653B2 (en) * 2002-11-08 2009-05-14 F. Hoffmann-La Roche Ag Substituted benzoxazinones and uses thereof
US7524877B2 (en) 2003-11-20 2009-04-28 Seroctin Research & Technology, Inc. Compounds for use in weight loss and appetite suppression in humans
AR048112A1 (es) * 2004-03-25 2006-03-29 Solvay Pharm Bv Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor
CA2615007A1 (en) * 2005-07-13 2007-01-18 F. Hoffmann-La Roche Ag Benzimidazole derivatives as 5-ht6,5-ht24
WO2016196593A1 (en) 2015-06-02 2016-12-08 E I Du Pont De Nemours And Company Substituted cyclic amides and their use as herbicides

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (de) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
FR2536749A1 (fr) * 1982-11-25 1984-06-01 Cerm Cent Europ Rech Mauvernay (amino-2 ethyl)-6 benzoxazolinones substituees, leur preparation et leurs applications en therapeutique
JPS59112973A (ja) * 1983-11-10 1984-06-29 Doujin Kagaku Kenkyusho:Kk テトラゾリウム塩化合物およびその化合物を用いる脱水素酵素の吸光光度定量法
GB8419797D0 (en) * 1984-08-03 1984-09-05 Beecham Group Plc Compounds
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
JPS6198476A (ja) * 1984-10-19 1986-05-16 Casio Comput Co Ltd カードターミナル
FR2588868B1 (fr) * 1985-10-21 1988-11-10 Negma Laboratoires Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
FR2637286A1 (fr) * 1988-10-04 1990-04-06 Adir Nouveaux derives benzoxazolinoniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2643634A1 (fr) * 1989-02-28 1990-08-31 Adir Nouveaux derives benzoxazolinoniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4037427A1 (de) * 1990-11-24 1992-05-27 Kali Chemie Pharma Gmbh Heterocyclisch substituierte piperazinoalkylbenzoxazin und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0478446A1 (de) 1992-04-01
US5296477A (en) 1994-03-22
EP0478446B1 (de) 1997-11-19
US5225409A (en) 1993-07-06
NZ239929A (en) 1994-12-22
GR3025948T3 (en) 1998-04-30
US5196434A (en) 1993-03-23
DE69128231T2 (de) 1998-06-18
ZA917701B (en) 1992-06-24
JPH06100548A (ja) 1994-04-12
FR2667068B1 (fr) 1994-09-09
JPH0786097B2 (ja) 1995-09-20
ES2111556T3 (es) 1998-03-16
IE913363A1 (en) 1992-04-08
PT99055A (pt) 1992-08-31
FR2667068A1 (fr) 1992-03-27
AU8471191A (en) 1992-04-16
PT99055B (pt) 1999-02-26
CA2052234A1 (fr) 1992-03-27
AU644212B2 (en) 1993-12-02
ATE160344T1 (de) 1997-12-15
DK0478446T3 (da) 1998-07-27

Similar Documents

Publication Publication Date Title
DE69128231D1 (de) Heterozyklische Alkylamine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten
DE69215595D1 (de) Isochinolin-5-yl-Sulfonsäureamide, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
DE69202313D1 (de) Naphthylethylharnstoff und Naphthylethylthioharnstoff Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten.
PT83647A (en) Process for the preparation of novel pharmaceutical benzimidazole derivatives and of pharmaceutical compositions containing the same
IL94433A0 (en) Aminophenol derivatives,their preparation and pharmaceutical compositions containing them
DE3783356D1 (de) Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
ATE144503T1 (de) Thiazolidin-2,4-dionderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
ATE10368T1 (de) Uracilderivate, verfahren zu ihrer herstellung und eine diese enthaltende pharmazeutische zubereitung.
ATE4642T1 (de) 2-hydroxyalkyl-3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE107298T1 (de) 3-aminochroman-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE69321861D1 (de) 3-Aminochroman-Spiroderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
ES8106003A1 (es) Procedimiento para la obtencion de acido fosfonohidroxiace- tico
ATE48994T1 (de) Benzimidazol-derivat, verfahren zu seiner herstellung und pharmazeutische zusammensetzung.
DE69214113D1 (de) Neue Pyrrolidinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE69214747D1 (de) N-(Isochinolein-5-yl)-Sulfonyl Azazykloalkane, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
ATE56707T1 (de) Imidazolverbindungen, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen.
ATE43350T1 (de) Nor-cholsaeure-derivate, verfahren zu ihrer herstellung, ihre anwendung und pharmazeutische zusammenstellungen, die sie enthalten.
ATE365162T1 (de) Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten
ES8200859A1 (es) Un procedimiento para la preparacion de derivados de ciclo- hexadieno
ATE26577T1 (de) 1-0-alkyl-3-amino-propan-1.2-diol-2-0phospholipide, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
HUT42099A (en) Process for preparing 2,3-diamino-2,3-dideoxy-hexose derivatives and pharmaceutical compositions containing thereof as active substances
ATE28647T1 (de) Chinazolinonderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln.
ATE104276T1 (de) Salze von acrylsaeure, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die sie enthalten und deren verwendung in der medizin.
ATE7908T1 (de) 4-phenoxy-3-hydroxy-butyramidoximderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel.
ATE73775T1 (de) 2-dithioalkyl-dihydropyridine, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee