DE69003172T2 - Synthetische Peptid-Antagonisten von Neurokinin A, deren Salze und respektive Herstellungsverfahren. - Google Patents

Synthetische Peptid-Antagonisten von Neurokinin A, deren Salze und respektive Herstellungsverfahren.

Info

Publication number
DE69003172T2
DE69003172T2 DE90830234T DE69003172T DE69003172T2 DE 69003172 T2 DE69003172 T2 DE 69003172T2 DE 90830234 T DE90830234 T DE 90830234T DE 69003172 T DE69003172 T DE 69003172T DE 69003172 T2 DE69003172 T2 DE 69003172T2
Authority
DE
Germany
Prior art keywords
dtrp
synthetic peptide
neurokinin
salts
manufacturing processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90830234T
Other languages
English (en)
Other versions
DE69003172D1 (de
Inventor
Paolo Rovero
Vittorio Pestellini
Carlo Alberto Maggi
Riccardo Patacchini
Paolo Santicioli
Sandro Giuliani
Alberto Meli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini Industrie Farmaceutiche Riunite SRL
Original Assignee
Menarini Industrie Farmaceutiche Riunite SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Industrie Farmaceutiche Riunite SRL filed Critical Menarini Industrie Farmaceutiche Riunite SRL
Application granted granted Critical
Publication of DE69003172D1 publication Critical patent/DE69003172D1/de
Publication of DE69003172T2 publication Critical patent/DE69003172T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE90830234T 1989-05-29 1990-05-25 Synthetische Peptid-Antagonisten von Neurokinin A, deren Salze und respektive Herstellungsverfahren. Expired - Fee Related DE69003172T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8909432A IT1233696B (it) 1989-05-29 1989-05-29 Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione

Publications (2)

Publication Number Publication Date
DE69003172D1 DE69003172D1 (de) 1993-10-14
DE69003172T2 true DE69003172T2 (de) 1994-01-05

Family

ID=11130065

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90830234T Expired - Fee Related DE69003172T2 (de) 1989-05-29 1990-05-25 Synthetische Peptid-Antagonisten von Neurokinin A, deren Salze und respektive Herstellungsverfahren.

Country Status (7)

Country Link
US (1) US5128447A (de)
EP (1) EP0401177B1 (de)
JP (1) JPH0317098A (de)
AT (1) ATE94169T1 (de)
DE (1) DE69003172T2 (de)
ES (1) ES2058873T3 (de)
IT (1) IT1233696B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ229552A (en) * 1988-06-20 1992-06-25 Merrell Dow Pharma Neurokinin a antagonists
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
US6218364B1 (en) 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
IT1241761B (it) * 1990-08-03 1994-02-01 Menarini Farma Ind Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione
FR2677361A1 (fr) * 1991-06-04 1992-12-11 Adir Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5521156A (en) * 1994-02-03 1996-05-28 Merrell Pharmaceuticals Inc. Cyclic neurokinin A antagonists
EP0672678B1 (de) * 1994-03-17 2000-10-25 Fujirebio Inc. Azapeptid-Derivate
JP4692976B2 (ja) * 2000-12-04 2011-06-01 株式会社シマノ 中通し竿
US7179784B2 (en) 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
GB0614970D0 (en) * 2006-07-27 2006-09-06 R & D Sosei Ltd Compounds For Use In Therapy
US10793614B2 (en) 2014-07-17 2020-10-06 Yissum Research Development Company of the Hebrew University ofJerusaIem Ltd. Antagonists of fish reproduction
US11352391B2 (en) 2017-09-21 2022-06-07 Dignify Therapeutics, Llc Compositions for inducing urinary voiding and defecation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481139A (en) * 1983-04-13 1984-11-06 Board Of Regents, The University Of Texas System Peptide antagonists of substance P
US4801613A (en) * 1985-06-13 1989-01-31 Nova Technology Limited Partnership Bradykinin antagonist peptides
US4665157A (en) * 1985-09-30 1987-05-12 Mcneilab, Inc. Peptide antagonists of neurokinin B
US4742156A (en) * 1985-09-30 1988-05-03 Mcneilab, Inc. Peptide antagonists of neurokinin B and opthalmic solutions containing them

Also Published As

Publication number Publication date
JPH0317098A (ja) 1991-01-25
IT1233696B (it) 1992-04-14
ES2058873T3 (es) 1994-11-01
EP0401177A1 (de) 1990-12-05
ATE94169T1 (de) 1993-09-15
US5128447A (en) 1992-07-07
DE69003172D1 (de) 1993-10-14
EP0401177B1 (de) 1993-09-08
IT8909432A0 (it) 1989-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee