IT1241761B - Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione - Google Patents
Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazioneInfo
- Publication number
- IT1241761B IT1241761B IT9455A IT945590A IT1241761B IT 1241761 B IT1241761 B IT 1241761B IT 9455 A IT9455 A IT 9455A IT 945590 A IT945590 A IT 945590A IT 1241761 B IT1241761 B IT 1241761B
- Authority
- IT
- Italy
- Prior art keywords
- neurokinin
- antagonists
- salts
- synthetic peptides
- manufacturing procedures
- Prior art date
Links
- HEAUFJZALFKPBA-JPQUDPSNSA-N (3s)-3-[[(2s,3r)-2-[[(2s)-6-amino-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2s)-1-[[(2s)-1-[[(2s)-1-[[2-[[(2s)-1-[[(2s)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amin Chemical compound C([C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)C(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)C1=CC=CC=C1 HEAUFJZALFKPBA-JPQUDPSNSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT9455A IT1241761B (it) | 1990-08-03 | 1990-08-03 | Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione |
| DE69104987T DE69104987T2 (de) | 1990-08-03 | 1991-07-26 | Synthetische peptide mit neurokinin a antagonistischer wirkung, deren salze und verfahren zu deren herstellung. |
| AU83191/91A AU8319191A (en) | 1990-08-03 | 1991-07-26 | Synthetic peptides that antagonize neurokinin a, their salts and their manufacturing processes |
| EP91914235A EP0541662B1 (en) | 1990-08-03 | 1991-07-26 | Synthetic peptides that antagonize neurokinin a, their salts and their manufacturing processes |
| ES91914235T ES2063519T3 (es) | 1990-08-03 | 1991-07-26 | Peptidos sinteticos que antagonizan neuroquinina a, sus sales y sus procedimientos de preparacion. |
| PCT/IT1991/000067 WO1992002546A1 (en) | 1990-08-03 | 1991-07-26 | Synthetic peptides that antagonize neurokinin a, their salts and their manufacturing processes |
| PT98558A PT98558A (pt) | 1990-08-03 | 1991-08-02 | Processo para a preparacao de peptidos sinteticos que antagonizam neuroquinina ae de composicoes farmaceuticas que os contem |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT9455A IT1241761B (it) | 1990-08-03 | 1990-08-03 | Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT9009455A0 IT9009455A0 (it) | 1990-08-03 |
| IT9009455A1 IT9009455A1 (it) | 1992-02-04 |
| IT1241761B true IT1241761B (it) | 1994-02-01 |
Family
ID=11130398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT9455A IT1241761B (it) | 1990-08-03 | 1990-08-03 | Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0541662B1 (it) |
| AU (1) | AU8319191A (it) |
| DE (1) | DE69104987T2 (it) |
| ES (1) | ES2063519T3 (it) |
| IT (1) | IT1241761B (it) |
| PT (1) | PT98558A (it) |
| WO (1) | WO1992002546A1 (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE155486T1 (de) * | 1991-08-13 | 1997-08-15 | Takeda Chemical Industries Ltd | Zyklische peptide und ihre verwendung |
| US5367053A (en) * | 1993-05-19 | 1994-11-22 | Houghten Pharmaceuticals, Inc. | Opioid peptide inhibitors |
| US5521156A (en) * | 1994-02-03 | 1996-05-28 | Merrell Pharmaceuticals Inc. | Cyclic neurokinin A antagonists |
| CA3139411A1 (en) * | 2019-05-21 | 2020-11-26 | Eyebio Korea | Novel peptide compound or pharmaceutically acceptable salt thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1233696B (it) * | 1989-05-29 | 1992-04-14 | Menarini Farma Ind | Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione |
-
1990
- 1990-08-03 IT IT9455A patent/IT1241761B/it active IP Right Grant
-
1991
- 1991-07-26 EP EP91914235A patent/EP0541662B1/en not_active Expired - Lifetime
- 1991-07-26 DE DE69104987T patent/DE69104987T2/de not_active Expired - Fee Related
- 1991-07-26 AU AU83191/91A patent/AU8319191A/en not_active Abandoned
- 1991-07-26 WO PCT/IT1991/000067 patent/WO1992002546A1/en active IP Right Grant
- 1991-07-26 ES ES91914235T patent/ES2063519T3/es not_active Expired - Lifetime
- 1991-08-02 PT PT98558A patent/PT98558A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992002546A1 (en) | 1992-02-20 |
| IT9009455A1 (it) | 1992-02-04 |
| IT9009455A0 (it) | 1990-08-03 |
| EP0541662A1 (en) | 1993-05-19 |
| AU8319191A (en) | 1992-03-02 |
| DE69104987T2 (de) | 1995-04-20 |
| EP0541662B1 (en) | 1994-11-02 |
| PT98558A (pt) | 1992-06-30 |
| DE69104987D1 (de) | 1994-12-08 |
| ES2063519T3 (es) | 1995-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950829 |