DE69002079D1 - 5,11-dihydro-6h-dipyrido (3,2-b:2',3'-e)diazepin-6-one und deren verwendung in der vorbeugung und behandlung von aids. - Google Patents

5,11-dihydro-6h-dipyrido (3,2-b:2',3'-e)diazepin-6-one und deren verwendung in der vorbeugung und behandlung von aids.

Info

Publication number
DE69002079D1
DE69002079D1 DE9090107098T DE69002079T DE69002079D1 DE 69002079 D1 DE69002079 D1 DE 69002079D1 DE 9090107098 T DE9090107098 T DE 9090107098T DE 69002079 T DE69002079 T DE 69002079T DE 69002079 D1 DE69002079 D1 DE 69002079D1
Authority
DE
Germany
Prior art keywords
dipyrido
dihydro
aids
prevention
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE9090107098T
Other languages
English (en)
Other versions
DE69002079T2 (de
Inventor
Karl D Dr Hargrave
Guenther Dr Schmidt
Wolfhard Dr Engel
Guenter Dr Trummlitz
Wolfgang Dr Eberlein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOEHRINGER INGELHEIM PHARMACEUTICALS Inc RIDGEFIELD CONN US
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
BOEHRINGER INGELHEIM PHARMACEUTICALS Inc RIDGEFIELD CONN US
Dr Karl Thomae GmbH
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BOEHRINGER INGELHEIM PHARMACEUTICALS Inc RIDGEFIELD CONN US, Dr Karl Thomae GmbH, Boehringer Ingelheim Pharmaceuticals Inc filed Critical BOEHRINGER INGELHEIM PHARMACEUTICALS Inc RIDGEFIELD CONN US
Publication of DE69002079D1 publication Critical patent/DE69002079D1/de
Application granted granted Critical
Publication of DE69002079T2 publication Critical patent/DE69002079T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE90107098T 1989-04-20 1990-04-12 5,11-Dihydro-6H-dipyrido [3,2-b:2',3'-e]diazepin-6-one und deren Verwendung in der Vorbeugung und Behandlung von AIDS. Expired - Lifetime DE69002079T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34097089A 1989-04-20 1989-04-20

Publications (2)

Publication Number Publication Date
DE69002079D1 true DE69002079D1 (de) 1993-08-05
DE69002079T2 DE69002079T2 (de) 1993-11-18

Family

ID=23335704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90107098T Expired - Lifetime DE69002079T2 (de) 1989-04-20 1990-04-12 5,11-Dihydro-6H-dipyrido [3,2-b:2',3'-e]diazepin-6-one und deren Verwendung in der Vorbeugung und Behandlung von AIDS.

Country Status (7)

Country Link
EP (1) EP0393529B1 (de)
JP (1) JP2851913B2 (de)
AT (1) ATE91128T1 (de)
CA (1) CA2014771C (de)
DE (1) DE69002079T2 (de)
DK (1) DK0393529T3 (de)
ES (1) ES2058656T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
CA2052946A1 (en) * 1990-10-19 1992-04-20 Karl G. Grozinger Method for the preparation of 5,11-dihydro-6h-dipyrido ¬3,2-b:2', 3'-e| ¬1,4|diazepines
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
DE4403311C1 (de) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
GB0001930D0 (en) * 2000-01-27 2000-03-22 Novartis Ag Organic compounds
DE10023492A1 (de) * 2000-05-09 2001-11-22 Schering Ag Aza- und Polyazanthranylamide und deren Verwendung als Arzneimittel
US7102009B2 (en) 2001-01-12 2006-09-05 Amgen Inc. Substituted amine derivatives and methods of use
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US6878714B2 (en) 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
US7105682B2 (en) 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
US7307088B2 (en) 2002-07-09 2007-12-11 Amgen Inc. Substituted anthranilic amide derivatives and methods of use
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4790339B2 (ja) * 2005-07-25 2011-10-12 リコーエレメックス株式会社 流量計測装置
US8247556B2 (en) 2005-10-21 2012-08-21 Amgen Inc. Method for preparing 6-substituted-7-aza-indoles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1542160A (fr) * 1966-10-31 1968-10-11 Thomae Gmbh Dr K Procédé de fabrication de nouvelles 5, 11-dihydro-6h-pyrido-[2, 3-b] [1, 4]-benzodiazépine-6-ones substituées en position 11

Also Published As

Publication number Publication date
DK0393529T3 (da) 1993-11-15
ATE91128T1 (de) 1993-07-15
ES2058656T3 (es) 1994-11-01
JP2851913B2 (ja) 1999-01-27
CA2014771A1 (en) 1990-10-20
DE69002079T2 (de) 1993-11-18
JPH0363276A (ja) 1991-03-19
EP0393529A1 (de) 1990-10-24
CA2014771C (en) 2000-08-01
EP0393529B1 (de) 1993-06-30

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