DE68929380T2 - Plättchen-spezifisches chimärisches immunglobulin - Google Patents

Plättchen-spezifisches chimärisches immunglobulin

Info

Publication number
DE68929380T2
DE68929380T2 DE68929380T DE68929380T DE68929380T2 DE 68929380 T2 DE68929380 T2 DE 68929380T2 DE 68929380 T DE68929380 T DE 68929380T DE 68929380 T DE68929380 T DE 68929380T DE 68929380 T2 DE68929380 T2 DE 68929380T2
Authority
DE
Germany
Prior art keywords
specific
immunglobulin
slide
image
specific chimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68929380T
Other languages
English (en)
Other versions
DE68929380D1 (de
Inventor
Barry S Coller
David M Knight
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NEW YORK RES FOUND, University of
Research Foundation of City University of New York
Janssen Biotech Inc
Original Assignee
NEW YORK RES FOUND, University of
Research Foundation of City University of New York
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NEW YORK RES FOUND, University of, Research Foundation of City University of New York, Centocor Inc filed Critical NEW YORK RES FOUND, University of
Publication of DE68929380D1 publication Critical patent/DE68929380D1/de
Application granted granted Critical
Publication of DE68929380T2 publication Critical patent/DE68929380T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04B—TRANSMISSION
    • H04B5/00—Near-field transmission systems, e.g. inductive or capacitive transmission systems
    • H04B5/20—Near-field transmission systems, e.g. inductive or capacitive transmission systems characterised by the transmission technique; characterised by the transmission medium
    • H04B5/24—Inductive coupling
    • H04B5/26—Inductive coupling using coils
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • G—PHYSICS
    • G08—SIGNALLING
    • G08B—SIGNALLING OR CALLING SYSTEMS; ORDER TELEGRAPHS; ALARM SYSTEMS
    • G08B13/00—Burglar, theft or intruder alarms
    • G08B13/22—Electrical actuation
    • G08B13/24—Electrical actuation by interference with electromagnetic field distribution
    • G08B13/2402—Electronic Article Surveillance [EAS], i.e. systems using tags for detecting removal of a tagged item from a secure area, e.g. tags for detecting shoplifting
    • G08B13/2465—Aspects related to the EAS system, e.g. system components other than tags
    • G08B13/2468—Antenna in system and the related signal processing
    • G08B13/2474—Antenna or antenna activator geometry, arrangement or layout
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01Q—ANTENNAS, i.e. RADIO AERIALS
    • H01Q7/00—Loop antennas with a substantially uniform current distribution around the loop and having a directional radiation pattern in a plane perpendicular to the plane of the loop
    • H01Q7/04—Screened antennas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Automation & Control Theory (AREA)
  • Computer Security & Cryptography (AREA)
  • Electromagnetism (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Burglar Alarm Systems (AREA)
  • Variable-Direction Aerials And Aerial Arrays (AREA)
DE68929380T 1988-05-18 1989-05-16 Plättchen-spezifisches chimärisches immunglobulin Expired - Lifetime DE68929380T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19572088A 1988-05-18 1988-05-18
PCT/US1989/002106 WO1989011538A1 (en) 1988-05-18 1989-05-16 Platelet-specific chimeric immunoglobulin

Publications (2)

Publication Number Publication Date
DE68929380D1 DE68929380D1 (de) 2002-04-25
DE68929380T2 true DE68929380T2 (de) 2002-11-21

Family

ID=22722511

Family Applications (2)

Application Number Title Priority Date Filing Date
DE68929380T Expired - Lifetime DE68929380T2 (de) 1988-05-18 1989-05-16 Plättchen-spezifisches chimärisches immunglobulin
DE2002199038 Active DE10299038I2 (de) 1988-05-18 1989-05-16 Pl{ttchen-spezifisches Chim{risches immunglobulin.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2002199038 Active DE10299038I2 (de) 1988-05-18 1989-05-16 Pl{ttchen-spezifisches Chim{risches immunglobulin.

Country Status (10)

Country Link
EP (2) EP0418316B1 (de)
JP (3) JP3115298B2 (de)
KR (1) KR940009084B1 (de)
AT (1) ATE214739T1 (de)
CA (1) CA1341357C (de)
DE (2) DE68929380T2 (de)
HK (1) HK1044563A1 (de)
LU (1) LU90955I2 (de)
NL (1) NL300102I2 (de)
WO (1) WO1989011538A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
WO1990006133A1 (en) * 1988-11-25 1990-06-14 Centocor, Inc. Heterobifunctional antibodies having specificity for platelets and thrombolytic agents
JPH05304982A (ja) * 1991-11-08 1993-11-19 Takara Shuzo Co Ltd キメラ型抗体
US5777085A (en) * 1991-12-20 1998-07-07 Protein Design Labs, Inc. Humanized antibodies reactive with GPIIB/IIIA
ES2293635T3 (es) 1992-11-16 2008-03-16 Centocor Inc. Metodo para reducir la inmunogenicidad de la region variable de anticuerpos.
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
JPH09504795A (ja) * 1993-11-05 1997-05-13 セントコール，インコーポレイテッド 血小板特異的キメラ免疫グロブリン及びその使用方法
US5694139A (en) * 1994-06-28 1997-12-02 Sony Corporation Short-distance communication antenna and methods of manufacturing and using the short-distance communication antenna
GB9519667D0 (en) * 1995-09-27 1995-11-29 Univ Manchester Pharmaceutical composition
JP4498471B2 (ja) * 1996-11-27 2010-07-07 アヴェンティス ファーマシューティカルズ インコーポレイテッド 抗―Ｘａ活性を有する化合物及び血小板凝集拮抗剤化合物を含有する製薬組成物
JP4660189B2 (ja) 2002-07-03 2011-03-30 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 抗血小板自己抗体およびそのインヒビターに関連する組成物、方法およびキット
CN1230447C (zh) * 2002-07-17 2005-12-07 阮长耿 识别血小板膜糖蛋白的单克隆抗体及其在抗血栓治疗中的应用
WO2010115866A1 (en) * 2009-04-06 2010-10-14 Novo Nordisk A/S Targeted delivery of factor viii proteins to platelets
US9150844B2 (en) * 2010-08-05 2015-10-06 Neeraj Maheshwari Protein fusion constructs possessing thrombolytic and anticoagulant properties
WO2012058418A2 (en) 2010-10-27 2012-05-03 The Research Foundation Of State University Of New York Compositions targeting the soluble extracellular domain of e-cadherin and related methods for cancer therapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6147500A (ja) * 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
CA1297815C (en) * 1985-06-07 1992-03-24 Barry S. Coller Fibrinogen blocking monoclonal antibody
CA1297816C (en) * 1985-06-14 1992-03-24 Barry S. Coller Platelet function inhibiting monoclonal antibody fragment

Also Published As

Publication number Publication date
NL300102I1 (nl) 2002-12-02
EP0418316A1 (de) 1991-03-27
EP1176201A3 (de) 2002-02-06
WO1989011538A1 (en) 1989-11-30
KR940009084B1 (ko) 1994-09-29
EP0418316B1 (de) 2002-03-20
NL300102I2 (nl) 2003-04-01
DE68929380D1 (de) 2002-04-25
CA1341357C (en) 2002-05-07
JP2000060555A (ja) 2000-02-29
KR900702594A (ko) 1990-12-07
JP3115298B2 (ja) 2000-12-04
DE10299038I2 (de) 2004-12-16
ATE214739T1 (de) 2002-04-15
JPH11180894A (ja) 1999-07-06
HK1044563A1 (zh) 2002-10-25
DE10299038I1 (de) 2003-02-20
JPH04501503A (ja) 1992-03-19
LU90955I2 (en) 2002-11-11
EP1176201A2 (de) 2002-01-30

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Legal Events

Date Code Title Description
V448 Application of spc
V457 Spc granted
V464 Spc expired