DE68928902D1 - Monoklonaler Antikörper gegen menschliches Lymphotoxin und seine Verwendung - Google Patents

Monoklonaler Antikörper gegen menschliches Lymphotoxin und seine Verwendung

Info

Publication number
DE68928902D1
DE68928902D1 DE68928902T DE68928902T DE68928902D1 DE 68928902 D1 DE68928902 D1 DE 68928902D1 DE 68928902 T DE68928902 T DE 68928902T DE 68928902 T DE68928902 T DE 68928902T DE 68928902 D1 DE68928902 D1 DE 68928902D1
Authority
DE
Germany
Prior art keywords
monoclonal antibody
human lymphotoxin
lymphotoxin
human
monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68928902T
Other languages
English (en)
Other versions
DE68928902T2 (de
Inventor
Kazuhiko Arai
Akira Fujiwara
Shosaku Motoda
Hiroyasu Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Denka Co Ltd
Original Assignee
Denki Kagaku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denki Kagaku Kogyo KK filed Critical Denki Kagaku Kogyo KK
Publication of DE68928902D1 publication Critical patent/DE68928902D1/de
Application granted granted Critical
Publication of DE68928902T2 publication Critical patent/DE68928902T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE68928902T 1988-06-20 1989-06-14 Monoklonaler Antikörper gegen menschliches Lymphotoxin und seine Verwendung Expired - Fee Related DE68928902T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63150021A JPH023698A (ja) 1988-06-20 1988-06-20 ヒトリンホトキシンに対するモノクローナル抗体及びそれら抗体を産生するハイブリドーマ、並びにそれら抗体を用いたヒトリンホトキシンの精製方法、測定方法及び測定試薬

Publications (2)

Publication Number Publication Date
DE68928902D1 true DE68928902D1 (de) 1999-02-25
DE68928902T2 DE68928902T2 (de) 1999-05-27

Family

ID=15487759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928902T Expired - Fee Related DE68928902T2 (de) 1988-06-20 1989-06-14 Monoklonaler Antikörper gegen menschliches Lymphotoxin und seine Verwendung

Country Status (4)

Country Link
US (1) US5188969A (de)
EP (1) EP0347728B1 (de)
JP (1) JPH023698A (de)
DE (1) DE68928902T2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4041187A1 (de) * 1990-12-21 1992-06-25 Basf Ag Neue tnf-peptide
TW257792B (de) * 1992-10-01 1995-09-21 Lilly Co Eli
AUPM388494A0 (en) * 1994-02-16 1994-03-10 Csl Limited Process for removing endotoxins
CL2007002926A1 (es) * 2006-10-12 2008-05-16 Genentech Inc Anticuerpo antilinfotoxina alfa (lt-alfa); composicion con el anticuerpo; hibridoma pta-7538; acido nucleico codificante del anticuerpo; vector y celula huesped que comprenden el acido nucleico; metodo para inhibir la proliferacion celular activada p
US20120094600A1 (en) 2010-10-19 2012-04-19 Welch Allyn, Inc. Platform for patient monitoring
CN110343695B (zh) * 2019-05-22 2023-04-25 青岛汉德森生物科技有限公司 杂交瘤细胞株及其制备方法和基于杂交瘤细胞株的乙肝表面抗原单克隆抗体及检测试剂盒

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920196A (en) * 1982-07-30 1990-04-24 Genentech, Inc. Human lymphotoxin
GB8318754D0 (en) * 1983-07-11 1983-08-10 Fagerhol M K F Human proteins anti-sera test kits
US4959457A (en) * 1984-05-31 1990-09-25 Genentech, Inc. Anti-lymphotoxin
IL75318A (en) * 1984-05-31 1994-08-26 Genentech Inc Recombinant human memotoxin and methods for its recombinant production
JPS638398A (ja) * 1986-06-30 1988-01-14 Denki Kagaku Kogyo Kk 生理活性ポリペプチド
EP0230781B1 (de) * 1985-12-24 1992-07-22 Denki Kagaku Kogyo Kabushiki Kaisha Lymphotoxin-Gen, Verfahren zu dessen Herstellung und Lymphotoxin
JP2548204B2 (ja) * 1987-06-27 1996-10-30 電気化学工業株式会社 新生理活性ポリペプチド
JPS638399A (ja) * 1986-06-30 1988-01-14 Denki Kagaku Kogyo Kk 生理活性ポリペプチド
JPS62181298A (ja) * 1986-02-05 1987-08-08 Kyowa Hakko Kogyo Co Ltd ヒトリンホトキシンポリペプチド誘導体
JPS62258324A (ja) * 1986-05-01 1987-11-10 Otsuka Pharmaceut Co Ltd 制ガン作用を有する糖蛋白質
DE3620656A1 (de) * 1986-06-20 1987-12-23 Basf Ag Polypeptide mit lymphotoxin-aktivitaet oder lymphotoxin-aehnlicher aktivitaet, ihre herstellung und verwendung
EP0335263A3 (de) * 1988-03-29 1990-06-13 Takeda Chemical Industries, Ltd. Monoklonale Antikörper gegen menschliches Lymphotoxin, Hybridom für seine Erzeugung, Antikörper gegen menschliches Lymphotoxin-C-Terminal-Peptid und Methode zum Nachweis von menschlichem Lyphotoxin damit

Also Published As

Publication number Publication date
EP0347728B1 (de) 1999-01-13
EP0347728A3 (de) 1990-06-13
DE68928902T2 (de) 1999-05-27
US5188969A (en) 1993-02-23
EP0347728A2 (de) 1989-12-27
JPH023698A (ja) 1990-01-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee