DE68924774D1 - Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden. - Google Patents

Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden.

Info

Publication number
DE68924774D1
DE68924774D1 DE68924774T DE68924774T DE68924774D1 DE 68924774 D1 DE68924774 D1 DE 68924774D1 DE 68924774 T DE68924774 T DE 68924774T DE 68924774 T DE68924774 T DE 68924774T DE 68924774 D1 DE68924774 D1 DE 68924774D1
Authority
DE
Germany
Prior art keywords
virus
cells
cyclodextrins
chemically modified
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68924774T
Other languages
English (en)
Other versions
DE68924774T2 (de
Inventor
Steven Roth
Paul Weisz
George Farnbach
David B Weiner
Mark Greene
William V Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of DE68924774D1 publication Critical patent/DE68924774D1/de
Application granted granted Critical
Publication of DE68924774T2 publication Critical patent/DE68924774T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE68924774T 1988-07-07 1989-07-06 Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden. Expired - Fee Related DE68924774T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21617688A 1988-07-07 1988-07-07
US37300589A 1989-06-28 1989-06-28
PCT/US1989/002944 WO1990000596A1 (en) 1988-07-07 1989-07-06 Method of modulating virus-host cell interactions using carbohydrates and carbohydrate derivatives

Publications (2)

Publication Number Publication Date
DE68924774D1 true DE68924774D1 (de) 1995-12-14
DE68924774T2 DE68924774T2 (de) 1996-05-02

Family

ID=26910735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924774T Expired - Fee Related DE68924774T2 (de) 1988-07-07 1989-07-06 Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden.

Country Status (10)

Country Link
EP (1) EP0423240B1 (de)
JP (1) JPH04500456A (de)
KR (1) KR900702005A (de)
AT (1) ATE129897T1 (de)
AU (1) AU636850B2 (de)
DE (1) DE68924774T2 (de)
IE (1) IE75688B1 (de)
PT (1) PT91088B (de)
WO (1) WO1990000596A1 (de)
ZA (1) ZA895187B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2067854T3 (es) * 1990-03-15 1995-04-01 Tanabe Seiyaku Co Polisulfato de derivado de ciclodextrina y procedimiento para preparar el mismo.
US5248675A (en) * 1990-03-15 1993-09-28 Tanabe Seiyaku Co., Ltd. Polysulfate of cyclodextrin derivative and process for preparing the same
GB9020872D0 (en) * 1990-09-25 1990-11-07 Ml Lab Plc Pharmaceutical compositions and use thereof
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
US5312837A (en) * 1991-01-29 1994-05-17 Genelabs Technologies, Inc. Method of treating viral infections with aryl macrocyclic compounds
JP2556236B2 (ja) * 1991-08-29 1996-11-20 田辺製薬株式会社 β−シクロデキストリン誘導体のポリ硫酸エステル及びその製法
WO1994003164A1 (en) * 1992-08-06 1994-02-17 Genelabs Technologies, Inc. Inhibition and treatment of infection by enveloped virus with calix(n) arene compounds
DE9316320U1 (de) * 1993-10-20 1994-01-20 Beni Med Natuerliche Heilmitte Kosmetische Zubereitung in Form von Lippenstiften mit antiviraler Wirkung
US5691316A (en) * 1994-06-01 1997-11-25 Hybridon, Inc. Cyclodextrin cellular delivery system for oligonucleotides
US6835717B2 (en) 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
DE10203999A1 (de) * 2002-02-01 2003-08-14 Nutricia Nv Cycloglycane
BE1030002B1 (fr) 2021-12-29 2023-09-01 Aquilon Pharmaceuticals Compositions inhalables comprenant un complexe de hpbcd et de budesonide ou ciclesonide pour le traitement ou la prevention d'une maladie virale respiratoire
WO2023118014A1 (en) 2021-12-20 2023-06-29 Aquilon Pharmaceuticals Inhalable compositions comprising a complex of hpbcd and budesonide or ciclesonide for the treatment or prevention of a respiratory viral disease or lipopolysaccharide-induced inflammation, in particular lipopolysaccharide-induced inflammation associated with a respiratory viral disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783446A (en) * 1985-11-22 1988-11-08 Neushul Mariculture Incorporated Method for the treatment of AIDS virus and other retroviruses

Also Published As

Publication number Publication date
EP0423240A4 (en) 1992-07-22
AU636850B2 (en) 1993-05-13
WO1990000596A1 (en) 1990-01-25
IE75688B1 (en) 1997-09-10
EP0423240B1 (de) 1995-11-08
KR900702005A (ko) 1990-12-05
ZA895187B (en) 1990-04-25
EP0423240A1 (de) 1991-04-24
IE892183L (en) 1990-01-07
PT91088A (pt) 1990-02-08
PT91088B (pt) 1995-01-31
ATE129897T1 (de) 1995-11-15
JPH04500456A (ja) 1992-01-30
DE68924774T2 (de) 1996-05-02
AU4044389A (en) 1990-02-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee