GB9020872D0 - Pharmaceutical compositions and use thereof - Google Patents

Pharmaceutical compositions and use thereof

Info

Publication number
GB9020872D0
GB9020872D0 GB909020872A GB9020872A GB9020872D0 GB 9020872 D0 GB9020872 D0 GB 9020872D0 GB 909020872 A GB909020872 A GB 909020872A GB 9020872 A GB9020872 A GB 9020872A GB 9020872 D0 GB9020872 D0 GB 9020872D0
Authority
GB
United Kingdom
Prior art keywords
agent
hiv
pharmaceutical compositions
polyanionic
against hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB909020872A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovata Ltd
Original Assignee
ML Laboratories PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ML Laboratories PLC filed Critical ML Laboratories PLC
Priority to GB909020872A priority Critical patent/GB9020872D0/en
Publication of GB9020872D0 publication Critical patent/GB9020872D0/en
Priority to AU86127/91A priority patent/AU653962B2/en
Priority to CA002092093A priority patent/CA2092093A1/en
Priority to PCT/GB1991/001627 priority patent/WO1992004909A1/en
Priority to EP91916829A priority patent/EP0550529A1/en
Priority to NZ239909A priority patent/NZ239909A/en
Priority to JP3515281A priority patent/JPH06502846A/en
Priority to IE334191A priority patent/IE913341A1/en
Priority to ZA917596A priority patent/ZA917596B/en
Priority to PT99058A priority patent/PT99058B/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

The invention provides an agent against HIV and related viruses, in dosage unit form, comprising CD4 or a CD4-like material and a polyanionic anti-HIV agent, the content of CD4 or CD4-like material in the agent being less than the anti-virally effective dose of the CD4 or CD4-like material alone. It has been found that when the CD4 or CD4-like material is used together with a polyanionic anti-HIV agent, the combination is more effective against HIV infection than would be the case if the anti-viral effect was simply additive.
GB909020872A 1990-09-25 1990-09-25 Pharmaceutical compositions and use thereof Pending GB9020872D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GB909020872A GB9020872D0 (en) 1990-09-25 1990-09-25 Pharmaceutical compositions and use thereof
JP3515281A JPH06502846A (en) 1990-09-25 1991-09-23 Pharmaceutical composition comprising CD4 and anti-HIV polyanion agent and method for using the same
EP91916829A EP0550529A1 (en) 1990-09-25 1991-09-23 Pharmaceutical composition comprising cd4 and a polyanionic anti-hiv agent and use thereof
CA002092093A CA2092093A1 (en) 1990-09-25 1991-09-23 Pharmaceutical composition comprising cd4 and a polyanionic anti-hiv agent and use thereof
PCT/GB1991/001627 WO1992004909A1 (en) 1990-09-25 1991-09-23 Pharmaceutical composition comprising cd4 and a polyanionic anti-hiv agent and use thereof
AU86127/91A AU653962B2 (en) 1990-09-25 1991-09-23 Pharmaceutical composition comprising CD4 and a polyanionic anti-HIV agent and use thereof
NZ239909A NZ239909A (en) 1990-09-25 1991-09-23 Anti hiv agents containing glycoprotein cd-4 and dextrin sulphate
IE334191A IE913341A1 (en) 1990-09-25 1991-09-24 Pharmaceutical compositions and use thereof
ZA917596A ZA917596B (en) 1990-09-25 1991-09-24 Pharmaceutical compositions
PT99058A PT99058B (en) 1990-09-25 1991-09-25 METHOD FOR PREPARING DEXTRIN SULPHATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909020872A GB9020872D0 (en) 1990-09-25 1990-09-25 Pharmaceutical compositions and use thereof

Publications (1)

Publication Number Publication Date
GB9020872D0 true GB9020872D0 (en) 1990-11-07

Family

ID=10682731

Family Applications (1)

Application Number Title Priority Date Filing Date
GB909020872A Pending GB9020872D0 (en) 1990-09-25 1990-09-25 Pharmaceutical compositions and use thereof

Country Status (10)

Country Link
EP (1) EP0550529A1 (en)
JP (1) JPH06502846A (en)
AU (1) AU653962B2 (en)
CA (1) CA2092093A1 (en)
GB (1) GB9020872D0 (en)
IE (1) IE913341A1 (en)
NZ (1) NZ239909A (en)
PT (1) PT99058B (en)
WO (1) WO1992004909A1 (en)
ZA (1) ZA917596B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272261A (en) * 1989-01-11 1993-12-21 Merrell Dow Pharmaceuticals Inc. Preparation of sulfated polysaccharide fractions
GB9209874D0 (en) * 1992-05-07 1992-06-24 Ml Lab Plc Pharmaceutical compositions
FR2838649B1 (en) 2002-04-19 2006-01-13 Commissariat Energie Atomique ANTI-HIV COMPOSITION, METHOD OF MANUFACTURE AND MEDICINAL PRODUCT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293826A3 (en) * 1987-06-02 1989-05-10 Stichting REGA V.Z.W. Therapeutic and prophylactic application of sulfated polysaccharides against aids
DE3808353A1 (en) * 1988-03-12 1989-09-21 Basf Ag COMBINATIONS OF POLYSULFATED HEPARINES IN THE FIGHT AGAINST RETROVIRUS INFECTIONS
AU3831889A (en) * 1988-06-10 1990-01-05 Biogen, Inc. Combinations of soluble t4 proteins and anti-retroviral agents and methods for treating or preventing aids, arc and hiv infection
IE75688B1 (en) * 1988-07-07 1997-09-10 Univ Pennsylvania Method of modulating virus-host cell interactions using carbohydrates and carbohydrate derivatives

Also Published As

Publication number Publication date
IE913341A1 (en) 1992-02-25
AU8612791A (en) 1992-04-15
PT99058A (en) 1992-08-31
NZ239909A (en) 1993-02-25
JPH06502846A (en) 1994-03-31
CA2092093A1 (en) 1992-03-26
AU653962B2 (en) 1994-10-20
EP0550529A1 (en) 1993-07-14
ZA917596B (en) 1992-05-27
PT99058B (en) 1999-02-26
WO1992004909A1 (en) 1992-04-02

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