DE68922044T2 - 2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall. - Google Patents
2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall.Info
- Publication number
- DE68922044T2 DE68922044T2 DE68922044T DE68922044T DE68922044T2 DE 68922044 T2 DE68922044 T2 DE 68922044T2 DE 68922044 T DE68922044 T DE 68922044T DE 68922044 T DE68922044 T DE 68922044T DE 68922044 T2 DE68922044 T2 DE 68922044T2
- Authority
- DE
- Germany
- Prior art keywords
- prevention
- treatment
- oxide derivatives
- diamino
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU87308A LU87308A1 (fr) | 1988-08-01 | 1988-08-01 | Nouveaux derives de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prevention de la chute des cheveux |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68922044D1 DE68922044D1 (de) | 1995-05-11 |
DE68922044T2 true DE68922044T2 (de) | 1995-08-03 |
Family
ID=19731083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68922044T Expired - Fee Related DE68922044T2 (de) | 1988-08-01 | 1989-07-12 | 2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4973474A (de) |
EP (1) | EP0356271B1 (de) |
JP (1) | JP2669903B2 (de) |
AT (1) | ATE120738T1 (de) |
CA (1) | CA1340445C (de) |
DE (1) | DE68922044T2 (de) |
ES (1) | ES2070186T3 (de) |
LU (1) | LU87308A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2033976A1 (en) * | 1989-06-12 | 1990-12-13 | Akihiro Ishino | Hair revitalizing tonic composition |
ES2063309T3 (es) * | 1989-07-12 | 1995-01-01 | Oreal | Derivados de pirimidina 3-oxido halogenados, su utilizacion para el tratamiento y la prevencion de la caida de los cabellos y para estimular su crecimiento. |
FR2662607B1 (fr) * | 1990-05-30 | 1992-08-28 | Oreal | Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 . |
FR2663327B1 (fr) * | 1990-06-19 | 1992-09-25 | Oreal | Nouveaux derives de diamino-2,4 triazine-1,3,5 et leur utilisation pour le traitement et la prevention de la chute des cheveux. |
LU87766A1 (fr) * | 1990-07-20 | 1992-03-11 | Oreal | Utilisation de derives de pyrimidine 3-oxyde pour freiner la chute des cheveux et compositions topiques mises en oeuvre |
US5043162A (en) * | 1990-09-05 | 1991-08-27 | Trager Seymour F | Hair growth promoter |
US5143650A (en) * | 1990-11-13 | 1992-09-01 | Aster, Inc. | Electrophoretic coatable sealant compositions comprising polyvinyl chloride and furnace carbon black |
FR2671082B1 (fr) * | 1990-12-28 | 1993-04-16 | Oreal | Agent a plusieurs composants ou kit de preparation de la forme sulfo-conjuguee de composes pyrimidino- ou triazino-n-oxyde et procede de mise en óoeuvre. |
FR2678929A1 (fr) * | 1991-07-11 | 1993-01-15 | Oreal | Compositions pour freiner la chute des cheveux et pour induire et stimuler leur croissance a base de derives de 2,4-diamino pyrimidine 3-oxyde, nouveaux derives 2,4-diamino pyrimidine 3-oxyde. |
US5451407A (en) * | 1993-06-21 | 1995-09-19 | Alza Corporation | Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug |
FR2711060B1 (fr) * | 1993-10-13 | 1995-11-17 | Oreal | Procédé pour modifier la pousse des poils et/ou des cheveux et compositions utilisables à cet effet. |
FR2732597B1 (fr) * | 1995-04-05 | 1997-05-16 | Oreal | Utilisation dans une composition en tant qu'activateur et/ou stabilisateur de cyclooxygenase d'au moins un derive de pyrimidine substitue en 6 |
US6159950A (en) * | 1998-10-16 | 2000-12-12 | Cornell Research Foundation, Inc. | Method of modulating hair growth |
FR2785802B1 (fr) | 1998-11-12 | 2002-10-31 | Oreal | 2-amino, 4-alkylamino pyrimidine 3-oxydes comme anti-inflammatoires |
FR2791671B1 (fr) | 1999-04-01 | 2001-05-11 | Oreal | Nouveaux composes derives d'esters d'acide benzoique, composition les comprenant et utilisation |
SE0104421D0 (sv) * | 2001-12-21 | 2001-12-21 | Ponsus Pharma Ab | New composition |
AU2003253075B2 (en) | 2002-06-21 | 2007-07-19 | L'oreal | Use of taurine or derivatives thereof for the treatment of alopecia |
US7326717B2 (en) * | 2003-05-06 | 2008-02-05 | L'oreal | Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof |
US20060193804A1 (en) * | 2005-02-24 | 2006-08-31 | L'oreal | Haircare use of cyclic amine derivatives |
DE102007015282B4 (de) * | 2007-03-29 | 2017-10-05 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Viskositätsregulator, Verfahren zu dessen Herstellung und dessen Verwendung |
FR2920309B1 (fr) | 2007-08-28 | 2010-05-28 | Galderma Res & Dev | Utilisation de travoprost pour traiter la chute des cheveux |
US8551463B2 (en) | 2007-10-22 | 2013-10-08 | Living Proof, Inc. | Hair care compositions and methods of treating hair |
FR2949052B1 (fr) | 2009-08-13 | 2015-03-27 | Oreal | Procede de traitement cosmetique du cuir chevelu. |
FR2953722B1 (fr) | 2009-12-16 | 2012-03-09 | Expanscience Lab | Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles |
DK2838533T3 (da) | 2012-04-16 | 2017-11-27 | Univ Case Western Reserve | Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet |
US9789116B2 (en) | 2013-10-15 | 2017-10-17 | Case Western Reserve University | Compositions and methods of modulating short-chain dehydrogenase activity |
CN106061474B (zh) | 2013-12-12 | 2020-03-03 | 赛尔米德有限公司 | 用类单萜治疗脱发的方法 |
US11690847B2 (en) | 2016-11-30 | 2023-07-04 | Case Western Reserve University | Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof |
WO2018145080A1 (en) | 2017-02-06 | 2018-08-09 | Case Western Reserve University | Compositions and methods of modulating short-chain dehydrogenase activity |
MX2021005982A (es) | 2018-11-21 | 2021-09-23 | Univ Case Western Reserve | Composiciones y metodos para modular la actividad de deshidrogenasas de cadena corta. |
FR3106058B1 (fr) * | 2020-01-09 | 2022-01-07 | Oreal | Procédé de traitement cosmétique |
EP3895685A1 (de) | 2020-04-14 | 2021-10-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Natürliche zusammensetzung zur haarwachstumsstimulation und haarverlustverhinderung und behandlung ohne konservierungsmittel |
EP3895686A1 (de) | 2020-04-14 | 2021-10-20 | FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. | Natürliche zusammensetzung zur stimulierung des haarwuchses und zur vorbeugung und behandlung von haarausfall |
AU2021275122A1 (en) | 2020-05-20 | 2022-12-15 | Board Of Regents Of The University Of Texas System | Compositions and methods of modulating short-chain dehydrogenase activity |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986000616A1 (en) * | 1984-07-13 | 1986-01-30 | Gail Sansone Bazzano | Substituted pyrimidine oxides useful for hair growth promotion |
-
1988
- 1988-08-01 LU LU87308A patent/LU87308A1/fr unknown
-
1989
- 1989-07-12 ES ES89402002T patent/ES2070186T3/es not_active Expired - Lifetime
- 1989-07-12 EP EP89402002A patent/EP0356271B1/de not_active Expired - Lifetime
- 1989-07-12 DE DE68922044T patent/DE68922044T2/de not_active Expired - Fee Related
- 1989-07-12 AT AT89402002T patent/ATE120738T1/de not_active IP Right Cessation
- 1989-07-28 JP JP1194437A patent/JP2669903B2/ja not_active Expired - Fee Related
- 1989-07-31 US US07/387,590 patent/US4973474A/en not_active Expired - Lifetime
- 1989-08-01 CA CA000607180A patent/CA1340445C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0278666A (ja) | 1990-03-19 |
LU87308A1 (fr) | 1990-03-13 |
ATE120738T1 (de) | 1995-04-15 |
US4973474A (en) | 1990-11-27 |
JP2669903B2 (ja) | 1997-10-29 |
CA1340445C (fr) | 1999-03-16 |
DE68922044D1 (de) | 1995-05-11 |
EP0356271B1 (de) | 1995-04-05 |
EP0356271A1 (de) | 1990-02-28 |
ES2070186T3 (es) | 1995-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |