DE68922044D1 - 2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall. - Google Patents

2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall.

Info

Publication number
DE68922044D1
DE68922044D1 DE68922044T DE68922044T DE68922044D1 DE 68922044 D1 DE68922044 D1 DE 68922044D1 DE 68922044 T DE68922044 T DE 68922044T DE 68922044 T DE68922044 T DE 68922044T DE 68922044 D1 DE68922044 D1 DE 68922044D1
Authority
DE
Germany
Prior art keywords
prevention
treatment
oxide derivatives
diamino
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68922044T
Other languages
English (en)
Other versions
DE68922044T2 (de
Inventor
Michel Hocquaux
Jacqueline Dumats
Quintino Gaetani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of DE68922044D1 publication Critical patent/DE68922044D1/de
Application granted granted Critical
Publication of DE68922044T2 publication Critical patent/DE68922044T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
DE68922044T 1988-08-01 1989-07-12 2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall. Expired - Fee Related DE68922044T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU87308A LU87308A1 (fr) 1988-08-01 1988-08-01 Nouveaux derives de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prevention de la chute des cheveux

Publications (2)

Publication Number Publication Date
DE68922044D1 true DE68922044D1 (de) 1995-05-11
DE68922044T2 DE68922044T2 (de) 1995-08-03

Family

ID=19731083

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922044T Expired - Fee Related DE68922044T2 (de) 1988-08-01 1989-07-12 2,4-Diamino-pyrimidin-3-oxid-Derivate und deren Verwendung bei der Behandlung und zur Verhütung von Haarfall.

Country Status (8)

Country Link
US (1) US4973474A (de)
EP (1) EP0356271B1 (de)
JP (1) JP2669903B2 (de)
AT (1) ATE120738T1 (de)
CA (1) CA1340445C (de)
DE (1) DE68922044T2 (de)
ES (1) ES2070186T3 (de)
LU (1) LU87308A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69009148T2 (de) * 1989-06-12 1994-12-22 Shiseido Co Ltd Haarwuchs stimulierender agent.
EP0408442B1 (de) * 1989-07-12 1994-08-31 L'oreal Halogenierte Pyrimidin-3-oxid-Derivate, deren Verwendung für die Behandlung und die Verhütung von Haarausfall und für die Wachstumsförderung von Haaren
FR2662607B1 (fr) * 1990-05-30 1992-08-28 Oreal Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 .
FR2663327B1 (fr) * 1990-06-19 1992-09-25 Oreal Nouveaux derives de diamino-2,4 triazine-1,3,5 et leur utilisation pour le traitement et la prevention de la chute des cheveux.
LU87766A1 (fr) * 1990-07-20 1992-03-11 Oreal Utilisation de derives de pyrimidine 3-oxyde pour freiner la chute des cheveux et compositions topiques mises en oeuvre
US5043162A (en) * 1990-09-05 1991-08-27 Trager Seymour F Hair growth promoter
US5143650A (en) * 1990-11-13 1992-09-01 Aster, Inc. Electrophoretic coatable sealant compositions comprising polyvinyl chloride and furnace carbon black
FR2671082B1 (fr) * 1990-12-28 1993-04-16 Oreal Agent a plusieurs composants ou kit de preparation de la forme sulfo-conjuguee de composes pyrimidino- ou triazino-n-oxyde et procede de mise en óoeuvre.
FR2678929A1 (fr) * 1991-07-11 1993-01-15 Oreal Compositions pour freiner la chute des cheveux et pour induire et stimuler leur croissance a base de derives de 2,4-diamino pyrimidine 3-oxyde, nouveaux derives 2,4-diamino pyrimidine 3-oxyde.
US5451407A (en) * 1993-06-21 1995-09-19 Alza Corporation Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug
FR2711060B1 (fr) * 1993-10-13 1995-11-17 Oreal Procédé pour modifier la pousse des poils et/ou des cheveux et compositions utilisables à cet effet.
FR2732597B1 (fr) * 1995-04-05 1997-05-16 Oreal Utilisation dans une composition en tant qu'activateur et/ou stabilisateur de cyclooxygenase d'au moins un derive de pyrimidine substitue en 6
US6159950A (en) * 1998-10-16 2000-12-12 Cornell Research Foundation, Inc. Method of modulating hair growth
FR2785802B1 (fr) * 1998-11-12 2002-10-31 Oreal 2-amino, 4-alkylamino pyrimidine 3-oxydes comme anti-inflammatoires
FR2791671B1 (fr) 1999-04-01 2001-05-11 Oreal Nouveaux composes derives d'esters d'acide benzoique, composition les comprenant et utilisation
SE0104421D0 (sv) * 2001-12-21 2001-12-21 Ponsus Pharma Ab New composition
ES2774911T3 (es) 2002-06-21 2020-07-23 Oreal Utilización de la taurina o derivados para el tratamiento de la alopecia
US7326717B2 (en) * 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
US20060193804A1 (en) * 2005-02-24 2006-08-31 L'oreal Haircare use of cyclic amine derivatives
DE102007015282B4 (de) * 2007-03-29 2017-10-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Viskositätsregulator, Verfahren zu dessen Herstellung und dessen Verwendung
FR2920309B1 (fr) 2007-08-28 2010-05-28 Galderma Res & Dev Utilisation de travoprost pour traiter la chute des cheveux
US8551463B2 (en) 2007-10-22 2013-10-08 Living Proof, Inc. Hair care compositions and methods of treating hair
FR2949052B1 (fr) 2009-08-13 2015-03-27 Oreal Procede de traitement cosmetique du cuir chevelu.
FR2953722B1 (fr) 2009-12-16 2012-03-09 Expanscience Lab Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles
DK2838533T3 (da) 2012-04-16 2017-11-27 Univ Case Western Reserve Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet
EP3057973B1 (de) 2013-10-15 2019-09-04 Case Western Reserve University Zusammensetzungen mit einem 15-pgdh-hemmer zur wundheilung
EP3079679B1 (de) 2013-12-12 2019-08-14 Cellmid Limited Verfahren zur behandlung von alopecia mit monoterpenoiden
WO2018102552A1 (en) 2016-11-30 2018-06-07 Case Western Reserve University Combinations of 15-pgdh inhibitors with corcosteroids and/or tnf inhibitors and uses thereof
CN110573154A (zh) 2017-02-06 2019-12-13 卡斯西部储备大学 调节短链脱氢酶活性的组合物和方法
CR20210328A (es) 2018-11-21 2021-12-02 Univ Case Western Reserve Composiciones y métodos para modular la actividad de deshidrogenasas de cadena corta
FR3106058B1 (fr) * 2020-01-09 2022-01-07 Oreal Procédé de traitement cosmétique
EP3895686A1 (de) 2020-04-14 2021-10-20 FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. Natürliche zusammensetzung zur stimulierung des haarwuchses und zur vorbeugung und behandlung von haarausfall
EP3895685A1 (de) 2020-04-14 2021-10-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Natürliche zusammensetzung zur haarwachstumsstimulation und haarverlustverhinderung und behandlung ohne konservierungsmittel
EP4153299A1 (de) 2020-05-20 2023-03-29 Rodeo Therapeutics Corporation Zusammensetzungen und verfahren zur modulation der aktivität von kurzkettiger dehydrogenase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187854A4 (de) * 1984-07-13 1987-01-22 Gail S Bazzano Substituierte pyrimidinoxide, einsetzbar zur haarwachsanregung.

Also Published As

Publication number Publication date
EP0356271A1 (de) 1990-02-28
JPH0278666A (ja) 1990-03-19
ES2070186T3 (es) 1995-06-01
JP2669903B2 (ja) 1997-10-29
EP0356271B1 (de) 1995-04-05
CA1340445C (fr) 1999-03-16
US4973474A (en) 1990-11-27
LU87308A1 (fr) 1990-03-13
ATE120738T1 (de) 1995-04-15
DE68922044T2 (de) 1995-08-03

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee